[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658493":3},{"organization":4,"outcomesModule":7,"designInfo":25,"detailedDescription":34,"studyPopulation":24,"armGroups":35,"interventions":47,"overallOfficials":24,"centralContacts":54,"locations":60,"responsibleParty":76,"collaborators":24,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":24,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":24,"enrollmentInfo":89,"targetDuration":24,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":24,"overallStatus":62,"whyStopped":24,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Tanta University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":24},[9],{"measure":10,"description":11,"timeFrame":12},"Degree of pain","Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents \"no pain\" while 10 represents \"the worst pain imaginable\").","6 months postoperatively",[14,17,21],{"measure":15,"description":16,"timeFrame":12},"Measurement of Quality of life","The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is a self-administered health status questionnaire and consists of 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). Accordingly, higher scores on the WOMAC indicate worse pain, stiffness, and functional limitation. The WOMAC will be assessed at each follow-up point",{"measure":18,"description":19,"timeFrame":20},"Patients' opioid medication use","Patients' opioid medication use will be evaluated before treatment and at 6 months after treatment.","6 months after treatment",{"measure":22,"description":23,"timeFrame":12},"Degree of patient satisfaction","Degree of patient satisfaction will be assessed on a 5-point Likert scale patient satisfaction (1, extremely dissatisfied; 2, unsatisfied; 3, neutral; 4, satisfied; 5, extremely satisfied)",null,{"allocation":26,"interventionModel":27,"interventionModelDescription":24,"primaryPurpose":28,"observationalModel":24,"timePerspective":24,"maskingInfo":29},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":30,"maskingDescription":24,"whoMasked":31},"DOUBLE",[32,33],"PARTICIPANT","OUTCOMES_ASSESSOR","Knee osteoarthritis (KOA) is a common musculoskeletal disorder characterized by degeneration of articular cartilage and the subchondral bone. It leads to pain, stiffness, and functional decline in the affected knee joints.\n\nCurrently, the classical 3- nerve protocol targeting the superior medial, superior lateral, and inferior medial genicular nerves is the most commonly used technique for radiofrequency procedures.\n\nTherefore, a five-needle Genicular nerve blocks (GNB) technique has been proposed to provide a more comprehensive blockade by targeting additional sensory branches.",[36,42],{"label":37,"type":38,"description":39,"interventionNames":40},"Group I (3-nerve-targeted group)","EXPERIMENTAL","Patients will receive 3-nerve protocol.",[41],"Other: 3-nerve-targeted group",{"label":43,"type":38,"description":44,"interventionNames":45},"Group II (5-nerve-targeted group)","Patients will receive 5-nerve protocol.",[46],"Other: 5-nerve-targeted group",[48,51],{"type":6,"name":49,"description":39,"armGroupLabels":50,"otherNames":24},"3-nerve-targeted group",[37],{"type":6,"name":52,"description":44,"armGroupLabels":53,"otherNames":24},"5-nerve-targeted group",[43],[55],{"name":56,"role":57,"phone":58,"phoneExt":24,"email":59},"Mohammed S Elsharkawy, MD","CONTACT","00201148207870","mselsharkawy@med.tanta.edu.eg",[61],{"facility":5,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"RECRUITING","Tanta","El-Gharbia","31527","Egypt","EG",{"type":69,"coordinates":70},"Point",[71,72],31.00192,30.78847,{"lat":72,"lon":71},[75],{"name":56,"role":57,"phone":58,"phoneExt":24,"email":59},{"type":77,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Mohammed Said ElSharkawy","Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.","100658493","3-needle-vs-5-needle-of-genicular-nerve-block-on-pain-and-quality-of-life-in-knee-osteoarthritis-100658493",false,"NCT07853170","3-Needle vs 5-Needle of Genicular Nerve Block on Pain and Quality of Life in Knee Osteoarthritis","A Randomized Controlled Trial Comparing the Effectiveness of 3-Needle vs 5-Needle of Genicular Nerve Block on Pain and Quality of Life in Knee Osteoarthritis","Inclusion Criteria:\n\n* Age ≥18 years.\n* Both sexes.\n* Patients with unilateral chronic knee pain for more than 3 months.\n* Patients received conservative treatment for at least 3 months.\n* Diagnosed Knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria, and grade greater than or equal to Kellgren-Lawrence grade 2.\n\nExclusion Criteria:\n\n* Chronic knee pain is due to causes other than KOA, such as connective tissue diseases, lumbar radicular neuropathy (spondylolisthesis, spinal stenosis), or sciatic pain.\n* Knee effusion.\n* Neuro\u002Fpsychiatric disorders.\n* History of intra-articular injection in the prior 3 months.\n* Prior knee surgery.\n* Active systemic or local knee infections; anticoagulant use.","ALL","18 Years",{"count":90,"type":91},80,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study aims to compare the 3-needle and 5-needle of genicular nerve block on pain and quality of life in Knee osteoarthritis (KOA).",[97,98,99,100,101,102],"3-Needle","5-Needle","Genicular Nerve Block","Pain","Quality of Life","Knee Osteoarthritis","2026-10-04",{"date":105,"type":106},"2026-10-06","ACTUAL",{"date":103,"type":106},{"date":109,"type":91},"2027-09-01",{"name":5,"class":6},1]