[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573616":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":10,"responsibleParty":21,"collaborators":10,"id":25,"slug":26,"hasResults":27,"nctId":28,"briefTitle":29,"officialTitle":29,"acronym":10,"eligibilityCriteria":30,"healthyVolunteers":27,"sex":31,"minAge":32,"maxAge":10,"enrollmentInfo":33,"targetDuration":10,"studyType":36,"phases":10,"briefSummary":37,"conditions":38,"keywords":40,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"group A",null,"patients who are assigned for transepithelial PRK",{"label":13,"type":10,"description":14,"interventionNames":10},"group B","patients who are mechanical PRK using a spatula",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Sandra Adel Nashed, resident doctor","CONTACT","+201276485120","sandraadelnashed0@gmail.com",{"type":22,"investigatorFullName":23,"investigatorTitle":24,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Sandra Adel Nashed","resident doctor at Assiut University hospital","100573616","a-comparative-study-between-laser-and-manual-removal-of-corneal-epithelium-for-photorefractive-keratectomy-100573616",false,"NCT06748599","A Comparative Study Between Laser and Manual Removal of Corneal Epithelium for Photorefractive Keratectomy","Inclusion Criteria:\n\n* • Age : older than 18 years old .\n\n  * Gender: Include both males and females.\n  * Stable refraction for at least 12 months .\n  * Intraocular pressure less than 21mmHg.\n  * A period without wearing contact lenses (more than 4 days for soft , more than 2 weeks for rigid contact lenses )\n  * No history of any Autoimmune disease .\n  * The refractive error must be one that can be treated by PRK\n\nExclusion Criteria:\n\n* \\_ patients with any eye disease (significant cataract or unstable glaucoma )\n\n  * uncontrolled external disease such as blepharitis, dry eye syndrome, and atopy\u002Fallergy.\n  * patients with Keratoconus and other abnormalities of the cornea such as corneal ectasias , thinning , edema , interstitial or neurotrophic keratitis and extensive vascularisation .\n  * Patients with active systemic connective tissue disease such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA)\n  * Ineligibility for Surgery: Exclude patients who are not suitable candidates for surgery .\n  * Consider excluding pregnant or lactating women .\n  * Patients unwilling to participate in the study .","ALL","18 Years",{"count":34,"type":35},64,"ESTIMATED","OBSERVATIONAL","Photorefractive keratectomy (PRK) is a laser eye surgery used to ablate the corneal stroma to correct visual refractive errors . PRK was developed in 1983 by Dr. Steven Trokel and colleagues and first performed in 1987 by Dr. Theo Seiler in Berlin. After receiving approval by the US Food and Drug Administration (FDA) in 1996, PRK was briefly the preferred surgical treatment of ametropia as it provided more predictable and stable results than incisional keratotomy. However, the number of PRK procedures fell in the late 1990s with the growing popularity of laser in situ keratomileusis (LASIK).\n\nThe study aims to compare the visual and refractive outcomes along with the pain score and patient satisfaction after photorefractive keratectomy in patients who underwent transepithelial or mechanical removal technique",[39],"Photorefractive Keratectomy",[41],"removal of corneal epithelium","NOT_YET_RECRUITING","2024-12-19",{"date":45,"type":46},"2024-12-27","ACTUAL",{"date":48,"type":35},"2025-01-01",{"date":50,"type":35},"2026-03-01",{"name":5,"class":6}]