[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645490":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":41,"responsibleParty":55,"collaborators":11,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":11,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":89,"whyStopped":11,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Fundacion Clinic per a la Recerca Biomédica","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Culinary-Nutritional Intervention Group","EXPERIMENTAL",null,[13],"Behavioral: Mediterranean diet-based culinary intervention",{"label":15,"type":16,"description":11,"interventionNames":17},"Control group","ACTIVE_COMPARATOR",[18],"Behavioral: Standard nutritional counseling",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","Mediterranean diet-based culinary intervention","Participants assigned to the culinary-nutritional intervention group will receive three individualized nutritional counseling sessions in Mediterranean diet, at baseline, 3 months, and 6 months, including health assessments and questionnaire administration at each visit. At the baseline visit, participants will receive a Mediterranean recipe booklet. Throughout the intervention, they will also receive educational videos featuring Mediterranean culinary preparations and cooking techniques.\n\nIn addition, participants will attend nine hands-on culinary medicine workshops over the 6-month intervention period. Workshops will be conducted every two weeks during the first 3 months (six workshops) and monthly during the last 3 months (three workshops). The workshops will focus on Mediterranean diet principles, healthy cooking skills, meal planning, food selection, and preparation of Mediterranean-style recipes to facilitate adherence to the dietary intervention.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Standard nutritional counseling","Participants assigned to the control group will receive standard nutritional counseling in Mediterranean diet, consisting of three individual consultations at baseline, 3 months, and 6 months to monitor adherence to dietary recommendations. At each visit, health parameters will be assessed and questionnaires will be administered to evaluate dietary behavior and related outcomes.\n\nAt baseline, 3 months, and 6 months, participants will undergo the same measurements as the intervention group. After completion of the study, participants in the control group will be provided with the Mediterranean recipe booklet and access to the educational videos on Mediterranean culinary preparations used in the intervention group.",[15],[30],{"name":31,"affiliation":32,"role":33},"Rosa M Casas Rodríguez, PhD","IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer (Hospital Clínic de Barcelona)","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":39,"email":40},"Victoria S Pinto Manzo, Msc","CONTACT","+34 932275400","2907","victoriasabinap@ub.edu",[42],{"facility":32,"status":11,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Barcelona","08035","Spain","ES",{"type":48,"coordinates":49},"Point",[50,51],2.15899,41.38879,{"lat":51,"lon":50},[54],{"name":36,"role":37,"phone":38,"phoneExt":39,"email":40},{"type":33,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Rosa Casas","Head of the Cardiovascular Risk, Nutrition and Aging Laboratory, Cardiovascular Risk Group","100645490","a-mediterranean-diet-based-culinary-intervention-in-adults-with-metabolic-syndrome-100645490",false,"NCT07702695","A Mediterranean Diet-Based Culinary Intervention in Adults With Metabolic Syndrome","Impact of a Mediterranean Diet-based Culinary Medicine Intervention on the Reversal of Metabolic Syndrome and Biomarkers of Inflammation, Oxidative Stress, and Aging","CUINAMET","Inclusion Criteria:\n\n* Men and women\n* Age between 30 and 60 years\n* Body mass index (BMI) between 20 and 35 kg\u002Fm²\n* Presence of metabolic syndrome defined as having at least three of the following criteria:\n\n  1. HDL cholesterol \\\u003C40 mg\u002FdL in men and \\\u003C50 mg\u002FdL in women\n  2. Fasting glucose \\>100 mg\u002FdL or use of hypoglycemic agents\n  3. Triglycerides ≥150 mg\u002FdL or use of lipid-lowering medication\n  4. Blood pressure ≥130\u002F85 mmHg\n  5. Waist circumference ≥102 cm in men and ≥88 cm in women\n\nExclusion Criteria:\n\n* Food allergies or intolerances to foods typical of the Mediterranean diet\n* Gluten intolerance or celiac disease\n* Adherence to a vegetarian or vegan diet\n* Eating disorders (including anorexia nervosa, bulimia nervosa, and binge eating disorder)\n* Moderate to severe psychiatric disorders that may compromise adherence to the intervention\n* History of cardiovascular events\n* BMI \\>35 kg\u002Fm²\n* Extreme dietary patterns in the last 3 months (e.g., Atkins diet, very high-protein diets)\n* Excessive alcohol consumption (\\>30 g\u002Fday for men and \\>20 g\u002Fday for women)\n* Pregnancy or lactation\n* Previous culinary training or formal culinary education","ALL","30 Years","60 Years",{"count":70,"type":71},120,"ESTIMATED","INTERVENTIONAL",[74],"NA","Metabolic syndrome is a major public health concern associated with an increased risk of cardiovascular disease, type 2 diabetes, and premature mortality. The Mediterranean diet has consistently demonstrated beneficial effects on metabolic health and is recommended as a dietary strategy for the prevention and management of metabolic syndrome. However, most interventions have focused on conventional nutritional counseling and have paid limited attention to the culinary and gastronomic skills required to translate dietary recommendations into sustainable eating behaviors.\n\nThis randomized controlled trial will evaluate the effectiveness of a Mediterranean diet-based nutritional intervention complemented by culinary medicine training sessions compared with a nutritional intervention alone in Spanish adults with metabolic syndrome. The culinary medicine component is designed to enhance participants' food preparation skills, confidence in cooking, and ability to incorporate Mediterranean dietary principles into their daily lives.\n\nParticipants will be followed for 6 months to assess changes in metabolic syndrome components and other metabolic health indicators. The study aims to determine whether the integration of culinary medicine education enhances the effectiveness of conventional nutritional counseling in improving metabolic syndrome outcomes and promoting long-term adherence to a Mediterranean dietary pattern",[77],"Metabolic Syndrome",[79,80,81,82,83,84,85,86,87,88],"metabolic syndrome","Mediterranean diet","culinary medicine","lifestyle intervention","diet therapy","cardiovascular risk","insulin resistance","inflammation","oxidative stress","obesity","NOT_YET_RECRUITING","2026-07-13",{"date":92,"type":93},"2026-07-14","ACTUAL",{"date":95,"type":71},"2026-09",{"date":97,"type":71},"2028-03",{"name":5,"class":6},1]