[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648334":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":28,"responsibleParty":44,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":10,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":70,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Guangzhou Medical University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"tubeless group",null,"Patients undergoing elective non-anatomic partial lung resection surgery using the Tubeless technique for maintaining spontaneous breathing anesthesia",{"label":13,"type":10,"description":14,"interventionNames":10},"double-lumen bronchial intubation group","Patients undergoing elective non-anatomic lung segmentectomy surgery using the double-lumen bronchial tube anesthesia method",[16],{"name":17,"affiliation":18,"role":19},"Lan Lan, PHD","The First Affiliated Hospital of Guangzhou Medical University","STUDY_DIRECTOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+8602083062566","lanlan@gzhmu.edu.cn",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Fengfa Yang, BS","yff18312377134@163.com",[29],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"the First Affiliated Hospital of Guangzhou Medical University","Guangzhou","Guangdong","510120","China","CN",{"type":37,"coordinates":38},"Point",[39,40],113.25,23.11667,{"lat":40,"lon":39},[43],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Fengfa Yang","Principal Investigator","100648334","a-prospective-clinical-study-observed-the-effects-of-tubeless-anesthesia-method-that-preserves-spontaneous-breathing-and-the-double-lumen-bronchial-intubation-on-the-brain-health-during-the-perioperative-period-100648334",false,"NCT07721038","A Prospective Clinical Study Observed the Effects of Tubeless Anesthesia Method That Preserves Spontaneous Breathing and the Double-lumen Bronchial Intubation on the Brain Health During the Perioperative Period","Tubeless Anesthesia With Preserved Spontaneous Breathing and the Construction of a Perioperative Brain Health Safety System for Thoracic Surgery Patients Study 2: A Prospective Clinical Study Observing the Impact of Two Anesthesia Techniques-Tubeless With Preserved Spontaneous Breathing Versus Double-Lumen Endotracheal Intubation-on Perioperative Brain Health","Inclusion Criteria:\n\n* Patient age: 18 - 75 years old\n* Patients meeting the standards of the American Society of Anesthesiologists (ASA) I-III grade and the New York Heart Association (NYHA) I-II class\n* Body Mass Index (BMI) \\\u003C 30 kg\u002Fm2\n* Intraoperative blood loss less than 300 ml\n* No severe cardiac or pulmonary dysfunction \\[first-second forced vital capacity (FEV1%) predicted value\\] \\> 50%, ejection fraction (EF) \\> 50%\n* No contraindications related to paravertebral nerve block and intercostal nerve block\n* Able to sign the informed consent form and possess communication, reading and writing abilities\n* Postoperative hospital stay of at least one day\n* No preoperative sleep disorders, no cognitive dysfunction (PSQI ≤ 10 points, PCS ≤ 38 points, MMSE \\> 27 points)\n\nExclusion Criteria:\n\n* Already diagnosed with a mental disorder or had a preoperative Mini-Mental State Examination (MMSE) score of less than 27\n* History of opioid abuse\n* Patients who were admitted to the ICU after surgery\n* Have severe cardiovascular, respiratory diseases\n* Experienced critical rescue during or after the surgery\n* Complicated with coagulation dysfunction, severe hypoxia or hypercapnia, or liver and kidney dysfunction\n* Difficult airway management\n* Changed anesthetic agent or surgical plan\n* Severe lacunar cerebral infarction, ischemic stroke or other neurological diseases\n* Changed anesthetic agent or surgical plan during the surgery;","ALL","18 Years","75 Years",{"count":59,"type":60},400,"ESTIMATED","6 Months","OBSERVATIONAL","This project conducts a prospective cohort study. By using multiple questionnaire survey methods such as the Pittsburgh Sleep Quality Index (PSQI) electronic wristband, QOR15, Pain Catastrophizing Scale (PCS), European Five-Dimensional Health Scale (EQ-5D), Revised American Pain Society Patient Follow-up Questionnaire (APS-POQ-R), Mini-Mental State Examination (MMSE), as well as perioperative stress and related indicators, hypothalamic-pituitary-adrenal axis (HPA) endocrine indicators, sublingual microcirculation, electroencephalogram, etc., comprehensive assessment is made of the correlations between the two different anesthesia methods of Tubeless retention of spontaneous breathing and double-lumen bronchial intubation and postoperative sleep, chronic pain and cognitive function, to construct a perioperative brain health safety system to improve prognosis; at the same time, optimize the perioperative sedation and analgesia plan and promote the postoperative brain health recovery of patients.",[65],"Brain Health",[67,68,69],"Tubeless anesthesia","double-lumen bronchial intubation","brain health","NOT_YET_RECRUITING","2026-07-19",{"date":73,"type":74},"2026-07-22","ACTUAL",{"date":76,"type":60},"2026-07-20",{"date":78,"type":60},"2028-12-31",{"name":5,"class":6},1]