[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573439":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":11,"locations":10,"responsibleParty":17,"collaborators":10,"id":19,"slug":20,"hasResults":21,"nctId":22,"briefTitle":23,"officialTitle":23,"acronym":10,"eligibilityCriteria":24,"healthyVolunteers":21,"sex":25,"minAge":26,"maxAge":10,"enrollmentInfo":27,"targetDuration":30,"studyType":31,"phases":10,"briefSummary":32,"conditions":33,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":10},{"fullName":5,"class":6},"Shanghai Minimally Invasive Surgery Center","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":10},"Rectal cancer patients receiving neoadjuvant therapy",null,[12],{"name":13,"role":14,"phone":15,"phoneExt":10,"email":16},"Jing Sun","CONTACT","+86-13524284622","sj117788@rjh.com.cn",{"type":18,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100573439","a-prospective-study-of-expression-profiling-based-assessment-of-the-efficacy-of-neoadjuvant-therapy-for-rectal-cancer-100573439",false,"NCT06746298","A Prospective Study of Expression Profiling-based Assessment of the Efficacy of Neoadjuvant Therapy for Rectal Cancer","Inclusion Criteria:\n\n* Age ≥18 years, male or infertile female\n* Patients with rectal adenocarcinoma diagnosed by colonoscopic biopsy\n* Neoadjuvant therapy according to guideline recommendations\n* Endoscopic biopsy with access to biopsy tissue for subsequent RNA-seq testing\n* Patients who do not have a combination of primary malignant tumors elsewhere.\n* Patients who understand the purpose of the trial, participate voluntarily and sign an informed consent form.\n\nExclusion Criteria:\n\n* Samples are not collected, stored, or processed in accordance with specified requirements\n* Sample does not meet the requirements for subsequent RNA-seq testing\n* Cases enrolled with a subsequent diagnosis other than rectal adenocarcinoma.\n* The patient refuses or is unable to complete the entire neoadjuvant treatment\n* Lack of post-neoadjuvant imaging results and lack of routine postoperative pathology results.\n* Other patients who, in the judgment of the investigator, do not meet the enrollment requirements","ALL","18 Years",{"count":28,"type":29},118,"ESTIMATED","60 Months","OBSERVATIONAL","This is a prospective study of expression profiling-based assessment of the efficacy of neoadjuvant therapy for rectal cancer.",[34,35],"Rectal Cancer","Neoadjuvant Therapy","NOT_YET_RECRUITING","2024-12-19",{"date":39,"type":40},"2024-12-24","ACTUAL",{"date":42,"type":29},"2025-01-01",{"date":44,"type":29},"2027-05-31",{"name":5,"class":6}]