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Molter","215-662-3116","melissa.molter@pennmedicine.upenn.edu",{"facility":759,"status":34,"city":760,"state":722,"zip":761,"country":38,"countryCode":39,"cosmosGeoPoint":762,"geoPoint":766,"contacts":767},"University of Pittsburgh Medical Center","Pittsburgh","15224",{"type":41,"coordinates":763},[764,765],-79.99589,40.44062,{"lat":765,"lon":764},[768],{"name":769,"role":24,"phone":770,"phoneExt":7,"email":771},"Adrienne DeRicco","4126928069","adrienne.dericco2@upmc.edu",{"facility":773,"status":34,"city":774,"state":775,"zip":776,"country":38,"countryCode":39,"cosmosGeoPoint":777,"geoPoint":781,"contacts":782},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":41,"coordinates":778},[779,780],-79.93275,32.77632,{"lat":780,"lon":779},[783],{"name":784,"role":24,"phone":785,"phoneExt":7,"email":786},"Ashley Warden","843-792-4349","jonesash@musc.edu",{"facility":788,"status":34,"city":789,"state":775,"zip":790,"country":38,"countryCode":39,"cosmosGeoPoint":791,"geoPoint":795,"contacts":796},"Prisma Health Children's Hospital - Midlands","Columbia","29203",{"type":41,"coordinates":792},[793,794],-81.03481,34.00071,{"lat":794,"lon":793},[797],{"name":798,"role":24,"phone":7,"phoneExt":7,"email":799},"Veronica Lipscomb","Veronica.Lipscomb@PrismaHealth.org",{"facility":801,"status":34,"city":802,"state":803,"zip":804,"country":38,"countryCode":39,"cosmosGeoPoint":805,"geoPoint":809,"contacts":810},"Vanderbilt University Medical Center","Nashville","Tennessee","37232",{"type":41,"coordinates":806},[807,808],-86.78444,36.16589,{"lat":808,"lon":807},[811],{"name":812,"role":24,"phone":813,"phoneExt":7,"email":814},"Brijesh Patel","615-343-4865","brijesh.patel@vumc.org",{"facility":816,"status":34,"city":817,"state":818,"zip":819,"country":38,"countryCode":39,"cosmosGeoPoint":820,"geoPoint":824,"contacts":825},"Dell Children's Medical Center of Central Texas","Austin","Texas","78723",{"type":41,"coordinates":821},[822,823],-97.74306,30.26715,{"lat":823,"lon":822},[826],{"name":827,"role":24,"phone":828,"phoneExt":7,"email":829},"Kristina \"Tina\" Adrean","512-324-9999","Kadrean@ascension.org",{"facility":831,"status":34,"city":832,"state":818,"zip":833,"country":38,"countryCode":39,"cosmosGeoPoint":834,"geoPoint":838,"contacts":839},"University of Texas Southwestern \u002F Children's Health","Dallas","75207",{"type":41,"coordinates":835},[836,837],-96.80667,32.78306,{"lat":837,"lon":836},[840],{"name":841,"role":24,"phone":842,"phoneExt":7,"email":843},"Keianna Brown","214-456-5489","Keianna.brown@utsouthwestern.edu",{"facility":845,"status":34,"city":832,"state":818,"zip":846,"country":38,"countryCode":39,"cosmosGeoPoint":847,"geoPoint":849,"contacts":850},"University of Texas Southwestern","75390",{"type":41,"coordinates":848},[836,837],{"lat":837,"lon":836},[851],{"name":852,"role":24,"phone":853,"phoneExt":7,"email":854},"Ashley Keller","214-648-6233","Ashley.Keller@UTSouthwestern.edu",{"facility":856,"status":34,"city":857,"state":818,"zip":858,"country":38,"countryCode":39,"cosmosGeoPoint":859,"geoPoint":863,"contacts":864},"Cook Children's Medical Center","Fort Worth","76104",{"type":41,"coordinates":860},[861,862],-97.32085,32.72541,{"lat":862,"lon":861},[865],{"name":866,"role":24,"phone":867,"phoneExt":7,"email":868},"Anna Reyes","682-885-6589","anna.reyes@cookchildrens.org",{"facility":870,"status":34,"city":871,"state":818,"zip":872,"country":38,"countryCode":39,"cosmosGeoPoint":873,"geoPoint":877,"contacts":878},"Baylor College of Medicine","Houston","77030",{"type":41,"coordinates":874},[875,876],-95.36327,29.76328,{"lat":876,"lon":875},[879],{"name":880,"role":24,"phone":881,"phoneExt":7,"email":882},"Tracy Mosely","832-822-3309","tlmosely@texaschildrens.org",{"facility":884,"status":34,"city":885,"state":886,"zip":887,"country":38,"countryCode":39,"cosmosGeoPoint":888,"geoPoint":892,"contacts":893},"Adult Cystic Fibrosis Center at the University of Utah","Salt Lake City","Utah","84112",{"type":41,"coordinates":889},[890,891],-111.89105,40.76078,{"lat":891,"lon":890},[894],{"name":895,"role":24,"phone":896,"phoneExt":7,"email":897},"Kristyn Packer","801-520-5106","kristyn.packer@hsc.utah.edu",{"facility":899,"status":34,"city":900,"state":901,"zip":902,"country":38,"countryCode":39,"cosmosGeoPoint":903,"geoPoint":907,"contacts":908},"Inova L.J. Murphy Pediatric CF Program","Fairfax","Virginia","22031",{"type":41,"coordinates":904},[905,906],-77.30637,38.84622,{"lat":906,"lon":905},[909],{"name":910,"role":24,"phone":911,"phoneExt":7,"email":912},"Colleen Mann","703-776-6485","colleen.mann@inova.org",{"facility":914,"status":34,"city":915,"state":901,"zip":916,"country":38,"countryCode":39,"cosmosGeoPoint":917,"geoPoint":921,"contacts":922},"Virginia Commonwealth University","Richmond","23219",{"type":41,"coordinates":918},[919,920],-77.46026,37.55376,{"lat":920,"lon":919},[923],{"name":924,"role":24,"phone":7,"phoneExt":7,"email":925},"Akilah Pierre-Louis","akilah.pierrelouis1@vcuhealth.org",{"facility":5,"status":34,"city":927,"state":928,"zip":929,"country":38,"countryCode":39,"cosmosGeoPoint":930,"geoPoint":934,"contacts":935},"Seattle","Washington","98105",{"type":41,"coordinates":931},[932,933],-122.33207,47.60621,{"lat":933,"lon":932},[936],{"name":937,"role":24,"phone":938,"phoneExt":7,"email":939},"Sharon McNamara","206-987-3921","sharon.mcnamara@seattlechildrens.org",{"facility":941,"status":34,"city":927,"state":928,"zip":942,"country":38,"countryCode":39,"cosmosGeoPoint":943,"geoPoint":945,"contacts":946},"University of Washington Medical Center","98195",{"type":41,"coordinates":944},[932,933],{"lat":933,"lon":932},[947],{"name":948,"role":24,"phone":949,"phoneExt":7,"email":950},"Lauren Bartlett","503-583-2869","lrejman@uw.edu",{"facility":952,"status":34,"city":953,"state":928,"zip":954,"country":38,"countryCode":39,"cosmosGeoPoint":955,"geoPoint":959,"contacts":960},"Providence Medical Group, Cystic Fibrosis Clinic","Spokane","99204",{"type":41,"coordinates":956},[957,958],-117.42908,47.65966,{"lat":958,"lon":957},[961],{"name":962,"role":24,"phone":963,"phoneExt":7,"email":964},"Joan Milton","509-474-4323","joan.milton@providence.org",{"facility":966,"status":34,"city":967,"state":968,"zip":969,"country":38,"countryCode":39,"cosmosGeoPoint":970,"geoPoint":974,"contacts":975},"West Virginia University - Morgantown","Morgantown","West Virginia","26507",{"type":41,"coordinates":971},[972,973],-79.9559,39.62953,{"lat":973,"lon":972},[976],{"name":977,"role":24,"phone":978,"phoneExt":7,"email":979},"Tammy Clark","3042935264","tclark@hsc.wvu.edu",{"facility":981,"status":34,"city":982,"state":983,"zip":984,"country":38,"countryCode":39,"cosmosGeoPoint":985,"geoPoint":989,"contacts":990},"University of Wisconsin","Madison","Wisconsin","53792",{"type":41,"coordinates":986},[987,988],-89.40123,43.07305,{"lat":988,"lon":987},[991],{"name":992,"role":24,"phone":993,"phoneExt":7,"email":994},"Melanie Nelson","608-265-4617","mnelson@pediatrics.wisc.edu",{"type":996,"investigatorFullName":997,"investigatorTitle":998,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"SPONSOR_INVESTIGATOR","Nicole Hamblett","Professor of Pediatrics, Division of Pulmonary and Sleep Medicine, UW School of Medicine Adjunct Professor, Biostatistics, UW School of Medicine Co-Executive Director, CF Therapeutics Development Network",[1000,1001,1003,1004,1005],{"name":11,"class":6},{"name":1002,"class":6},"Florida State University",{"name":17,"class":6},{"name":20,"class":6},{"name":1006,"class":6},"Cystic Fibrosis Foundation","100554861","a-research-study-to-advance-the-cf-therapeutics-pipeline-for-people-without-modulators-100554861",false,"NCT06504589","A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators","Consent\n\nA. Written informed consent (and assent when applicable) obtained from participant or participant's legal guardian\n\nB. Is willing and able to adhere to the study visit schedule and other protocol requirements\n\nDemographics\n\nA. ≥ 12 years of age at Visit 1\n\nMedical History\n\nA. For persons of child-bearing potential: must not be pregnant at Visit 1 or plan to get pregnant during the 12-month study period\n\nDisease History\n\nA. Documentation of a CF diagnosis as evidenced by one or more clinical features consistent with the CF phenotype and one or more of the following criteria:\n\n* Sweat chloride ≥ 60 mEq\u002Fliter by quantitative pilocarpine iontophoresis test (QPIT)\n* Two well-characterized disease-causing pathogenic variants in the CFTR gene\n\nor\n\n* One well-characterized disease-causing mutation and a second CFTR variant (with variable or uncharacterized disease-causing potential) and sweat ≥ 30 mmol\u002Fliter with permission of the study sponsor-investigators\n\nB. Clinically stable with no significant changes in health status within the 28 days prior to and including Visit 1\n\nC. Does not have a history of lung transplantation\n\nConcomitant Medications\n\nA. Not genetically eligible for a CFTR modulator according to product label indications and\u002For No use of CFTR modulator for 28 days prior to Visit 1 with no intent to start or restart during the study period\n\nB. No use of an investigational drug within 90 days prior to and including Visit 1\n\nC. Not currently participating in an interventional drug or device trial. Participation in long-term safety follow-up studies (without redosing) and\u002For behavioral intervention trials is allowed.\n\nD. No initiation of new chronic therapy (e.g., ibuprofen, azithromycin, inhaled tobramycin, Cayston®) within 28 days prior to and including Visit 1\n\nE. No acute use of antibiotics (oral, inhaled or IV) or acute use of systemic corticosteroids for respiratory tract symptoms within 28 days prior to and including Visit 1","ALL","12 Years",{"count":1016,"type":1017},400,"ESTIMATED","OBSERVATIONAL","The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to inform CF research, help design CF clinical trials and support the development of new treatments for people with CF who do not take CFTR modulators.\n\nAnother goal of this study is to learn about research involvement for people with CF who do not take CFTR modulators, engage them in research, and give them an opportunity to learn about what is involved in participating in a CF research study.",[1021],"Cystic Fibrosis",[1023,1024],"ineligible and\u002For not taking CFTR modulators","People with CF","2025-09-25",{"date":1027,"type":1028},"2025-10-01","ACTUAL",{"date":1030,"type":1028},"2024-09-18",{"date":1032,"type":1017},"2029-08-14",{"name":997,"class":6},68]