[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650626":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Beijing Friendship Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"GERD Retrospective Cohort",null,"A retrospective cohort of approximately 5,000 patients with a confirmed diagnosis of gastroesophageal reflux disease (GERD) treated at Beijing Friendship Hospital was established using data extracted from the prospective clinical registry of the National Clinical Research Center for Digestive Diseases.",[13],"Other: Clinical Data Collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Clinical Data Collection","Data on clinical symptoms, treatment details, and long-term follow-up outcomes were retrospectively extracted from electronic medical records (EMRs) and institutional databases.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Zhi Zheng, Attending surgon","CONTACT","+86-13811132175","zhengzhi@ccmu.edu.cn",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Beijing Friendship Hospital, Capital Medical University","RECRUITING","Beijing","Beijing Municipality","100050","China","CN",{"type":35,"coordinates":36},"Point",[37,38],116.39723,39.9075,{"lat":38,"lon":37},[41],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","JunZhang","Chief Surgeon","100650626","a-retrospective-analysis-of-patients-with-gastroesophageal-reflux-disease-based-on-a-prospective-clinical-dataset-100650626",false,"NCT07749989","A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset","Establishing an Innovative Cohort of Chinese Patients With Gastroesophageal Reflux Disease Based on the Prospective Database of the National Clinical Research Center for Digestive Diseases: A Retrospective Study","Inclusion Criteria:\n\n* Aged between 18 and 90 years old.\n* Patients were required to present with at least one typical symptom of gastroesophageal reflux disease (GERD)-such as heartburn, regurgitation, or non-cardiac chest pain-and to have presented to Beijing Friendship Hospital for the evaluation and management of these symptoms.\n* Received treatment, including pharmacological therapy and anti-reflux surgery, at Beijing Friendship Hospital.\n* Voluntary signing of informed consent, agreeing to the use of clinical information for future research.\n\nExclusion Criteria:\n\n* Female patients who were pregnant or lactating.\n* Patients with significantly incomplete or missing critical clinical data.\n* Patients with an equivocal or unconfirmed diagnosis of GERD.\n* Current neurologic or cognitive impairment, which would preclude ability to obtain informed consent.\n* Refusal to participate in the study.","ALL","18 Years","90 Years",{"count":57,"type":58},5000,"ESTIMATED","OBSERVATIONAL","This retrospective, observational cohort study aimed to establish a comprehensive research cohort utilizing a large-scale prospective clinical registry. The primary objectives were to characterize the real-world demographic profiles, clinical features, psychological characteristics, and treatment patterns of Chinese patients with gastroesophageal reflux disease (GERD), as well as to evaluate post-treatment improvements in both GERD symptoms and psychological well-being. The study retrospectively enrolled approximately 5,000 patients with a confirmed diagnosis of GERD, with data derived from the prospective registry of the National Clinical Research Center for Digestive Diseases. Investigators systematically extracted data on baseline demographics, clinical presentations, objective diagnostic findings, preoperative psychological status, surgical complications, and longitudinal follow-up outcomes for all eligible patients. Ultimately, this study sought to provide high-quality, China-specific evidence to inform the precise phenotyping of GERD and to guide standardized, individualized clinical decision-making.",[62],"Gastroesophageal Reflux Disease",[62,64,65,66,67],"Retrospective Cohort","Surgical Treatment","Real-World Data","Quality of Life","2026-08-05",{"date":70,"type":71},"2026-08-06","ACTUAL",{"date":73,"type":71},"2026-04-17",{"date":75,"type":58},"2027-05",{"name":5,"class":6},1]