[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635705":3},{"organization":4,"outcomesModule":7,"designInfo":90,"detailedDescription":40,"studyPopulation":93,"armGroups":94,"interventions":116,"overallOfficials":40,"centralContacts":125,"locations":132,"responsibleParty":772,"collaborators":774,"id":777,"slug":778,"hasResults":779,"nctId":780,"briefTitle":781,"officialTitle":782,"acronym":783,"eligibilityCriteria":784,"healthyVolunteers":779,"sex":785,"minAge":786,"maxAge":40,"enrollmentInfo":787,"targetDuration":790,"studyType":791,"phases":40,"briefSummary":792,"conditions":793,"keywords":795,"overallStatus":135,"whyStopped":40,"lastUpdateSubmitDate":799,"lastUpdatePostDateStruct":800,"startDateStruct":803,"completionDateStruct":805,"leadSponsor":807,"locationsCount":808},{"fullName":5,"class":6},"Sanofi","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":33,"otherOutcomes":40},[9,13,16,19,22,26,29],{"measure":10,"description":11,"timeFrame":12},"Part 1: Descriptive Characterization of Participants With Asthma Across the Spectrum of Severities","Descriptive Statistical Analyses may include sociodemographic and clinical characteristics, comorbidities, exacerbation history, medication burden, biomarkers and lung function.","Part 1: At baseline",{"measure":14,"description":15,"timeFrame":12},"Part 1: ACQ-5 Scores to Evaluate Characteristics of Participants With Asthma","ACQ-5 is a 5-question survey. The five ACQ-5 questions are scored on a 6-point scale (0 = good control, 6 = poor control), and the overall score is the mean of the five responses. Participant's scores are then classified into three prescribed groups as having well-controlled asthma (score ≤ 0.75); partially controlled asthma (score 0.75-1.5), or not well controlled asthma (score \\>1.5). A change in ACQ-5 score of 0.5 is considered the minimal clinically important difference (MCID)",{"measure":17,"description":18,"timeFrame":12},"Part 1: Mini-Asthma Quality of Life Questionnaire (Mini-AQLQ) Scores to Evaluate Characteristics of Participants With Asthma","The Asthma Quality of Life Questionnaire (AQLQ) includes 32 items, The mini-AQLQ is a reduced version of the AQLQ which includes 15 items. The questions correspond to 4 dimensions of health: symptoms (5 items), limitation of usual activities (4 items), emotional function (3 items) and environmental stimuli (3 items). The response options for each item are on an equidistant scale of 7 points, where 1 corresponds to the maximum disability and 7 to the absence of disability. Higher scores indicating better quality of life (less impairment) and lower scores indicating worse quality of life (greater impairment).",{"measure":20,"description":21,"timeFrame":12},"Part 1: Physician Global Assessment of Asthma Severity and Symptom Control","Asthma severity, asthma control, and comorbidity will be assessed using three global impression of severity items: Physician Global Impression of Severity (PhGIS) - asthma severity. PhGIS - asthma control, and PhGIS - comorbidity.",{"measure":23,"description":24,"timeFrame":25},"Part 2: Descriptive Statistical Analysis of Difference in Asthma Symptom Control (ACQ-5) Between Part 2 Cohorts A1 and A2","Data on participant's asthma symptoms and control will be collected via the ACQ-5, 5-question survey. The five ACQ-5 questions are scored on a 6-point scale (0 = good control, 6 = poor control), and the overall score is the mean of the five responses. Participant's scores are then classified into three prescribed groups as having well-controlled asthma (score \\\u003C=0.75); partially controlled asthma (score 0.75-1.5), or not well controlled asthma (score \\>1.5). A change in ACQ-5 score of 0.5 is considered the MCID.","Part 2: At Weeks 52 and 104",{"measure":27,"description":28,"timeFrame":25},"Part 2: Number of Participants Analyzed with Treatment Utilization Pattern between Part 2 Cohorts A1 and A2","Treatment utilization will include systemic corticosteroids (SCS), ICS, and short-acting beta agonists (SABA). Number of participants with various treatment utilization pattern will be assessed and reported.",{"measure":30,"description":31,"timeFrame":32},"Part 2: Descriptive Statistical Analysis of Difference in Change in Pre-Bronchodilator Forced Expiratory Volume in 1 Second (Pre-BD FEV₁) between Part 2 Cohorts B1 and Cohort B2","Pre-BD FEV₁ is the forced expiratory volume in 1 second measured by spirometry prior to bronchodilator administration.","Part-2: At Weeks 52 and 104",[34,38,41,43,45,47,50,52,54,57,60,62,66,69,72,74,76,79,82,85,88],{"measure":35,"description":36,"timeFrame":37},"Part 1: Physician-Reported Outcomes to Characterize Physician Perspectives","The treatment preferences for participant profiles, an assessment of perceived disease burden on participants, an evaluation of barriers to optimal treatment, and treatment adherence and persistence will be collected from the main treating physician.","Part 1: From 12 months prior to study enrollment",{"measure":39,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Their Demographics and Clinical Characteristics",null,{"measure":42,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Their Disease Burden, Health Status, Treatment Experiences",{"measure":44,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Medication Use",{"measure":46,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Their Lifestyle and Environmental Influences",{"measure":48,"description":49,"timeFrame":37},"Part 1: Change From Baseline in Patient Global Impression of Severity (PGIS) Score","The PGIS is a single question asking the participant to rate their severity and symptom control. The PGIS is a 5-point ordinal scale ranging from 1 (No symptoms) to 5 (Very severe symptoms). Higher scores indicate greater symptom severity.",{"measure":51,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Inhaled and Systemic Corticosteroid Use",{"measure":53,"description":40,"timeFrame":37},"Part 1: Number of Participants Characterised by Healthcare Resource Utilization (HCRU)",{"measure":55,"description":56,"timeFrame":37},"Part 1: Change From Baseline in Work Productivity and Activity Impairment Questionnaire (WPAI) Score","The WPAI-Asthma is an Asthma-specific, patient-reported measure of work absenteeism, work presenteeism (reduced productivity while working due to illness), total work productivity loss (absenteeism plus presenteeism), and overall activity impairment over the prior 7 days. The WPAI-Asthma questionnaire score represents the percentage of impairment, from 0 to 100%. Higher scores represent greater impairment and less productivity.",{"measure":58,"description":40,"timeFrame":59},"Part 2: Descriptive Characterization Including Sociodemographics and Disease Characteristics and Treatment History.","Part 2: At baseline",{"measure":61,"description":40,"timeFrame":25},"Part 2: Annualized Exacerbation Rates at Week 52 and 104",{"measure":63,"description":64,"timeFrame":65},"Part 2: Changes From Baseline to Week 104 in Pre and Post Bronchodilator Forced Expiratory Volume in 1 Second (FEV1)","FEV1 will be measured in Liters. Change from baseline: mean of (value of observed FEV1 at treatment duration minus baseline value).","Part 2: From baseline to week 52 and week 104",{"measure":67,"description":68,"timeFrame":65},"Part 2: Number of Participants With Significant Changes in Asthma Treatment Patterns at Week 52 and Week 104","Changes in treatment patterns including use of SCS, ICS, other asthma therapies, and rescue medication. Treatment escalation (for example \\[e.g.\\], ICS dose changes, addition of asthma therapies, or biologic prescription), treatment adherence, and treatment persistence will be assessed from baseline to Week 52 and Week 104 in participants with Asthma.",{"measure":70,"description":71,"timeFrame":65},"Part 2: Changes in Physician Global Assessment of Asthma Severity, Symptom Control and Comorbidities (PhGIS)","Asthma severity, asthma control, and comorbidity will be assessed using three global impression of severity items: PhGIS - asthma severity. PhGIS - asthma control, and PhGIS - comorbidity.",{"measure":73,"description":49,"timeFrame":25},"Part 2: Number of Participants With Comorbidities and Burden of Comorbidities Based on the Participant Survey Using the PGIS scale",{"measure":75,"description":71,"timeFrame":25},"Part 2: Number of Participants With Comorbidities and Burden of Comorbidities Based on the Physician Survey Using the PhGIS Scale",{"measure":77,"description":40,"timeFrame":78},"Part 2: Number of Participants Analyzed for Changes in Inhaled and Systemic Corticosteroid Burden","Part 2: From baseline up to week 104",{"measure":80,"description":81,"timeFrame":65},"Part 2: Changes in Physician-reported HCRU (Hospitalizations, Outpatient and Emergency Visits)","Data about HCRU associated with medical encounters will be collected by physicians from medical records. The data collected will include setting, department, type of specialist, the reasons and duration of hospitalizations, outpatient and emergency room (ER) visits.",{"measure":83,"description":84,"timeFrame":25},"Part 2: Changes in Patient-Reported Outcomes to Characterize Disease Evolution","PROs used will include but not limited to ACQ-5, mini-AQLQ. ACQ-5 questions are scored on a 6-point scale (0 = good control, 6 = poor control), Mean of the five responses is the overall score. Scores are then classified into three groups as having well-controlled asthma (score \\\u003C= 0.75); partially controlled asthma (score 0.75-1.5), or not well controlled asthma (score \\>1.5). AQLQ includes 32 items, The mini-AQLQ is a reduced version of the AQLQ which includes 15 items. The questions correspond to 4 dimensions of health: symptoms (5 items), limitation of usual activities (4 items), emotional function (3 items) and environmental stimuli (3 items). The response options for each item are on an equidistant scale of 7 points, where 1 corresponds to the maximum disability and 7 to the absence of disability.",{"measure":86,"description":87,"timeFrame":65},"Part 2: Changes in Participant Survey Response","Participant survey collecting demographics, clinical characteristics, disease burden, health status, treatment experiences, medication use and burden, work and school impacts, lifestyle and environmental influences, impacts on daily life, PGIS for each comorbidity and burden of comorbidities, inhaled and systemic corticosteroid burden (frequency of use, routes of administration, treatment satisfaction), and HCRU office visits, hospitalizations, outpatient and emergency visits will be collected from medical records.",{"measure":89,"description":40,"timeFrame":25},"Part 2: Changes in Biomarker Level",{"allocation":40,"interventionModel":40,"interventionModelDescription":40,"primaryPurpose":40,"observationalModel":91,"timePerspective":92,"maskingInfo":40},"COHORT","PROSPECTIVE","Enrollment into Part 1 is planned to achieve a balanced distribution of participants across participating regions, to the extent feasible. In addition, enrollment is intended to include pediatric participants, adolescents, and adults. Enrollment into Part 2 is planned to achieve a balanced distribution of participants across participating regions, to the extent feasible.",[95,100,104,108,112],{"label":96,"type":40,"description":97,"interventionNames":98},"Part-1: Participants With Asthma","Participants receiving treatment with low-, medium-, or high-dose inhaled corticosteroids (ICS) and\u002For biologic therapies as part of standard of care (SoC) for the management of asthma in routine clinical practice.",[99],"Other: Procedure: Investigational Procedures",{"label":101,"type":40,"description":102,"interventionNames":103},"Part-2: A1- Uncontrolled Asthma Cohort","Participants receiving SoC with Asthma Control Questionnaire-5 (ACQ-5) threshold of greater than or equal to (\\>=)1.5",[99],{"label":105,"type":40,"description":106,"interventionNames":107},"Part-2: A2- Controlled Asthma Cohort","Participants receiving SoC with Asthma Control Questionnaire-5 (ACQ-5) threshold of less than (\\\u003C)1.5",[99],{"label":109,"type":40,"description":110,"interventionNames":111},"Part-2: B1- Type-2 (T2) High Asthma Cohort","Participants receiving SoC with elevated T2 biomarkers",[99],{"label":113,"type":40,"description":114,"interventionNames":115},"Part-2: B2- Type-2 Low Asthma Cohort","Participants receiving SoC with low T2 biomarkers",[99],[117,122],{"type":118,"name":119,"description":120,"armGroupLabels":121,"otherNames":40},"OTHER","Procedure: Investigational Procedures","Participant- and physician-reported outcomes will be collected per protocol. No Investigational Medicinal Product (IMP) administration.",[96],{"type":118,"name":119,"description":123,"armGroupLabels":124,"otherNames":40},"Participant- and physician-reported outcomes, blood samples\u002Flung tests and other optional assessments will be collected per protocol. No IMP administration.",[101,105,109,113],[126],{"name":127,"role":128,"phone":129,"phoneExt":130,"email":131},"Trial Transparency email recommended-Toll free for US & Canada","CONTACT","800-633-1610","6","Contact-US@sanofi.com",[133,147,158,168,177,186,196,205,214,223,232,241,250,260,269,278,287,296,301,307,313,319,325,331,337,343,352,360,365,371,380,389,398,407,416,425,434,444,454,464,474,483,493,503,513,523,533,542,550,560,569,578,588,597,607,617,627,637,646,655,661,670,679,689,701,711,721,733,745,752,762],{"facility":134,"status":135,"city":136,"state":137,"zip":138,"country":139,"countryCode":140,"cosmosGeoPoint":141,"geoPoint":146,"contacts":40},"Trinity Clinical Research, LLC - Bessemer - Site Number: 840150","RECRUITING","Bessemer","Alabama","35022","United States","US",{"type":142,"coordinates":143},"Point",[144,145],-86.95444,33.40178,{"lat":145,"lon":144},{"facility":148,"status":149,"city":150,"state":151,"zip":152,"country":139,"countryCode":140,"cosmosGeoPoint":153,"geoPoint":157,"contacts":40},"Chandler Clinical Trials - Site Number: 840106","WITHDRAWN","Chandler","Arizona","85224",{"type":142,"coordinates":154},[155,156],-111.84125,33.30616,{"lat":156,"lon":155},{"facility":159,"status":160,"city":161,"state":151,"zip":162,"country":139,"countryCode":140,"cosmosGeoPoint":163,"geoPoint":167,"contacts":40},"Del Sol Research Management, LLC - Mesa - Site Number: 840123","ACTIVE_NOT_RECRUITING","Mesa","85206",{"type":142,"coordinates":164},[165,166],-111.82264,33.42227,{"lat":166,"lon":165},{"facility":169,"status":135,"city":170,"state":151,"zip":171,"country":139,"countryCode":140,"cosmosGeoPoint":172,"geoPoint":176,"contacts":40},"Orso Health - Scottsdale - Site Number: 840133","Scottsdale","85254",{"type":142,"coordinates":173},[174,175],-111.89903,33.50921,{"lat":175,"lon":174},{"facility":178,"status":160,"city":179,"state":151,"zip":180,"country":139,"countryCode":140,"cosmosGeoPoint":181,"geoPoint":185,"contacts":40},"Sun City Clinical Trials - Elite - Site Number: 840120","Sun City","85351",{"type":142,"coordinates":182},[183,184],-112.27182,33.59754,{"lat":184,"lon":183},{"facility":187,"status":160,"city":188,"state":189,"zip":190,"country":139,"countryCode":140,"cosmosGeoPoint":191,"geoPoint":195,"contacts":40},"FOMAT - Huntington Asthma & Allergy Center - Site Number: 840158","California City","California","91107",{"type":142,"coordinates":192},[193,194],-117.9859,35.1258,{"lat":194,"lon":193},{"facility":197,"status":160,"city":198,"state":189,"zip":199,"country":139,"countryCode":140,"cosmosGeoPoint":200,"geoPoint":204,"contacts":40},"Imax Clinical Trials - Site Number: 840109","La Palma","90623",{"type":142,"coordinates":201},[202,203],-118.04673,33.8464,{"lat":203,"lon":202},{"facility":206,"status":160,"city":207,"state":189,"zip":208,"country":139,"countryCode":140,"cosmosGeoPoint":209,"geoPoint":213,"contacts":40},"Downtown LA Research - Site Number: 840161","Los Angeles","90017",{"type":142,"coordinates":210},[211,212],-118.24368,34.05223,{"lat":212,"lon":211},{"facility":215,"status":160,"city":216,"state":189,"zip":217,"country":139,"countryCode":140,"cosmosGeoPoint":218,"geoPoint":222,"contacts":40},"Newport Native MD, Inc. - Site Number: 840101","Newport Beach","92663",{"type":142,"coordinates":219},[220,221],-117.92895,33.61891,{"lat":221,"lon":220},{"facility":224,"status":160,"city":225,"state":189,"zip":226,"country":139,"countryCode":140,"cosmosGeoPoint":227,"geoPoint":231,"contacts":40},"Pasadena Clinical Trials - Site Number: 840116","Pasadena","91101",{"type":142,"coordinates":228},[229,230],-118.14452,34.14778,{"lat":230,"lon":229},{"facility":233,"status":149,"city":234,"state":189,"zip":235,"country":139,"countryCode":140,"cosmosGeoPoint":236,"geoPoint":240,"contacts":40},"Valiance Clinical Research (JPJ Research) - Site Number: 840135","Tarzana","91356",{"type":142,"coordinates":237},[238,239],-118.55397,34.17334,{"lat":239,"lon":238},{"facility":242,"status":160,"city":243,"state":189,"zip":244,"country":139,"countryCode":140,"cosmosGeoPoint":245,"geoPoint":249,"contacts":40},"Clinical Research of California - Site Number: 840145","Walnut Creek","94598",{"type":142,"coordinates":246},[247,248],-122.06496,37.90631,{"lat":248,"lon":247},{"facility":251,"status":160,"city":252,"state":253,"zip":254,"country":139,"countryCode":140,"cosmosGeoPoint":255,"geoPoint":259,"contacts":40},"Cornerstone Research Institute, LLC - Site Number: 840152","Altamonte Springs","Florida","32701",{"type":142,"coordinates":256},[257,258],-81.36562,28.66111,{"lat":258,"lon":257},{"facility":261,"status":160,"city":262,"state":253,"zip":263,"country":139,"countryCode":140,"cosmosGeoPoint":264,"geoPoint":268,"contacts":40},"3SYNC Research - Boca Raton - Site Number: 840148","Boca Raton","33431",{"type":142,"coordinates":265},[266,267],-80.0831,26.35869,{"lat":267,"lon":266},{"facility":270,"status":160,"city":271,"state":253,"zip":272,"country":139,"countryCode":140,"cosmosGeoPoint":273,"geoPoint":277,"contacts":40},"Meris Clinical Research - Site Number: 840167","Brandon","33511",{"type":142,"coordinates":274},[275,276],-82.28592,27.9378,{"lat":276,"lon":275},{"facility":279,"status":160,"city":280,"state":253,"zip":281,"country":139,"countryCode":140,"cosmosGeoPoint":282,"geoPoint":286,"contacts":40},"Finlay Medical Research - Site Number: 840107","Greenacres City","33467",{"type":142,"coordinates":283},[284,285],-80.12532,26.62368,{"lat":285,"lon":284},{"facility":288,"status":160,"city":289,"state":253,"zip":290,"country":139,"countryCode":140,"cosmosGeoPoint":291,"geoPoint":295,"contacts":40},"EMDA Clinical Research - Site Number: 840113","Miami","33126",{"type":142,"coordinates":292},[293,294],-80.19366,25.77427,{"lat":294,"lon":293},{"facility":297,"status":160,"city":289,"state":253,"zip":290,"country":139,"countryCode":140,"cosmosGeoPoint":298,"geoPoint":300,"contacts":40},"Finlay Medical Research - Miami - Site Number: 840110",{"type":142,"coordinates":299},[293,294],{"lat":294,"lon":293},{"facility":302,"status":160,"city":289,"state":253,"zip":303,"country":139,"countryCode":140,"cosmosGeoPoint":304,"geoPoint":306,"contacts":40},"Care Research Inc. - Site Number: 840103","33130",{"type":142,"coordinates":305},[293,294],{"lat":294,"lon":293},{"facility":308,"status":160,"city":289,"state":253,"zip":309,"country":139,"countryCode":140,"cosmosGeoPoint":310,"geoPoint":312,"contacts":40},"L&A Morales Healthcare, Inc - Site Number: 840102","33142",{"type":142,"coordinates":311},[293,294],{"lat":294,"lon":293},{"facility":314,"status":160,"city":289,"state":253,"zip":315,"country":139,"countryCode":140,"cosmosGeoPoint":316,"geoPoint":318,"contacts":40},"MedOne Clinical Research - Site Number: 840122","33145",{"type":142,"coordinates":317},[293,294],{"lat":294,"lon":293},{"facility":320,"status":160,"city":289,"state":253,"zip":321,"country":139,"countryCode":140,"cosmosGeoPoint":322,"geoPoint":324,"contacts":40},"D&H National Research Centers INC - Site Number: 840128","33155",{"type":142,"coordinates":323},[293,294],{"lat":294,"lon":293},{"facility":326,"status":160,"city":289,"state":253,"zip":327,"country":139,"countryCode":140,"cosmosGeoPoint":328,"geoPoint":330,"contacts":40},"Research Institute Of South Florida - Site Number: 840149","33173",{"type":142,"coordinates":329},[293,294],{"lat":294,"lon":293},{"facility":332,"status":160,"city":289,"state":253,"zip":333,"country":139,"countryCode":140,"cosmosGeoPoint":334,"geoPoint":336,"contacts":40},"Valencia Medical & Research Center, Corp - Site Number: 840153","33174",{"type":142,"coordinates":335},[293,294],{"lat":294,"lon":293},{"facility":338,"status":160,"city":289,"state":253,"zip":339,"country":139,"countryCode":140,"cosmosGeoPoint":340,"geoPoint":342,"contacts":40},"Correa Research Center, Inc. - Site Number: 840141","33186",{"type":142,"coordinates":341},[293,294],{"lat":294,"lon":293},{"facility":344,"status":160,"city":345,"state":253,"zip":346,"country":139,"countryCode":140,"cosmosGeoPoint":347,"geoPoint":351,"contacts":40},"Pro Care Research Center - Site Number: 840143","Miami Gardens","33014",{"type":142,"coordinates":348},[349,350],-80.2456,25.94204,{"lat":350,"lon":349},{"facility":353,"status":160,"city":354,"state":253,"zip":346,"country":139,"countryCode":140,"cosmosGeoPoint":355,"geoPoint":359,"contacts":40},"3SYNC Research - Miami Lakes - Site Number: 840146","Miami Lakes",{"type":142,"coordinates":356},[357,358],-80.30866,25.90871,{"lat":358,"lon":357},{"facility":361,"status":160,"city":354,"state":253,"zip":346,"country":139,"countryCode":140,"cosmosGeoPoint":362,"geoPoint":364,"contacts":40},"Deluxe Health Center - Site Number: 840117",{"type":142,"coordinates":363},[357,358],{"lat":358,"lon":357},{"facility":366,"status":160,"city":354,"state":253,"zip":367,"country":139,"countryCode":140,"cosmosGeoPoint":368,"geoPoint":370,"contacts":40},"MedQuest Translation Sciences, LLC - Site Number: 840162","33016",{"type":142,"coordinates":369},[357,358],{"lat":358,"lon":357},{"facility":372,"status":160,"city":373,"state":253,"zip":374,"country":139,"countryCode":140,"cosmosGeoPoint":375,"geoPoint":379,"contacts":40},"Biscayne Clinical Research - Site Number: 840157","North Miami Beach","33169",{"type":142,"coordinates":376},[377,378],-80.16255,25.93315,{"lat":378,"lon":377},{"facility":381,"status":160,"city":382,"state":253,"zip":383,"country":139,"countryCode":140,"cosmosGeoPoint":384,"geoPoint":388,"contacts":40},"CTMD Research, Inc - Site Number: 840147","Palm Springs","33406",{"type":142,"coordinates":385},[386,387],-80.09615,26.6359,{"lat":387,"lon":386},{"facility":390,"status":160,"city":391,"state":253,"zip":392,"country":139,"countryCode":140,"cosmosGeoPoint":393,"geoPoint":397,"contacts":40},"Edward Jenner Research Group, LLC - Site Number: 840169","Plantation","33317",{"type":142,"coordinates":394},[395,396],-80.23184,26.13421,{"lat":396,"lon":395},{"facility":399,"status":160,"city":400,"state":253,"zip":401,"country":139,"countryCode":140,"cosmosGeoPoint":402,"geoPoint":406,"contacts":40},"Mark J. Pamer D.O., LLC - Site Number: 840121","Port Saint Lucie","34986",{"type":142,"coordinates":403},[404,405],-80.35033,27.29393,{"lat":405,"lon":404},{"facility":408,"status":160,"city":409,"state":253,"zip":410,"country":139,"countryCode":140,"cosmosGeoPoint":411,"geoPoint":415,"contacts":40},"TBC Research Corp - Site Number: 840132","Tamarac","33321",{"type":142,"coordinates":412},[413,414],-80.24977,26.21286,{"lat":414,"lon":413},{"facility":417,"status":160,"city":418,"state":253,"zip":419,"country":139,"countryCode":140,"cosmosGeoPoint":420,"geoPoint":424,"contacts":40},"Avita Clinical Research - Tampa - Site Number: 840125","Tampa","33613",{"type":142,"coordinates":421},[422,423],-82.45843,27.94752,{"lat":423,"lon":422},{"facility":426,"status":160,"city":427,"state":253,"zip":428,"country":139,"countryCode":140,"cosmosGeoPoint":429,"geoPoint":433,"contacts":40},"Palm Beach Medical & Research Center, Inc. - Site Number: 840165","West Palm Beach","33409",{"type":142,"coordinates":430},[431,432],-80.05337,26.71534,{"lat":432,"lon":431},{"facility":435,"status":160,"city":436,"state":437,"zip":438,"country":139,"countryCode":140,"cosmosGeoPoint":439,"geoPoint":443,"contacts":40},"The Allergy Center at Brookstone - Site Number: 840114","Columbus","Georgia","31904",{"type":142,"coordinates":440},[441,442],-84.98771,32.46098,{"lat":442,"lon":441},{"facility":445,"status":160,"city":446,"state":447,"zip":448,"country":139,"countryCode":140,"cosmosGeoPoint":449,"geoPoint":453,"contacts":40},"Next Innovation Clinical Research - Chicago - Site Number: 840159","Chicago","Illinois","60616",{"type":142,"coordinates":450},[451,452],-87.65005,41.85003,{"lat":452,"lon":451},{"facility":455,"status":160,"city":456,"state":457,"zip":458,"country":139,"countryCode":140,"cosmosGeoPoint":459,"geoPoint":463,"contacts":40},"Bluegrass Allergy Care - Lexington - Site Number:840112","Lexington","Kentucky","40509",{"type":142,"coordinates":460},[461,462],-84.47772,37.98869,{"lat":462,"lon":461},{"facility":465,"status":135,"city":466,"state":467,"zip":468,"country":139,"countryCode":140,"cosmosGeoPoint":469,"geoPoint":473,"contacts":40},"Columbia Medical Practice - Site Number: 840172","Columbia","Maryland","21045",{"type":142,"coordinates":470},[471,472],-76.83942,39.24038,{"lat":472,"lon":471},{"facility":475,"status":160,"city":476,"state":467,"zip":477,"country":139,"countryCode":140,"cosmosGeoPoint":478,"geoPoint":482,"contacts":40},"Velocity Clinical Research - Rockville - Site Number: 840163","Rockville","20854",{"type":142,"coordinates":479},[480,481],-77.15276,39.084,{"lat":481,"lon":480},{"facility":484,"status":135,"city":485,"state":486,"zip":487,"country":139,"countryCode":140,"cosmosGeoPoint":488,"geoPoint":492,"contacts":40},"University of Michigan - Ann Arbor - Site Number: 840140","Ann Arbor","Michigan","48109",{"type":142,"coordinates":489},[490,491],-83.74088,42.27756,{"lat":491,"lon":490},{"facility":494,"status":160,"city":495,"state":496,"zip":497,"country":139,"countryCode":140,"cosmosGeoPoint":498,"geoPoint":502,"contacts":40},"Montana Medical Research - Site Number: 840137","Missoula","Montana","59808",{"type":142,"coordinates":499},[500,501],-113.994,46.87215,{"lat":501,"lon":500},{"facility":504,"status":160,"city":505,"state":506,"zip":507,"country":139,"countryCode":140,"cosmosGeoPoint":508,"geoPoint":512,"contacts":40},"Primary Clinical Research, LLC - Papillion - Site Number: 840168","Papillion","Nebraska","68046",{"type":142,"coordinates":509},[510,511],-96.04224,41.15444,{"lat":511,"lon":510},{"facility":514,"status":160,"city":515,"state":516,"zip":517,"country":139,"countryCode":140,"cosmosGeoPoint":518,"geoPoint":522,"contacts":40},"MedCorps Asthma and Pulmonary Specialists LLC - Sewell - Site Number: 840136","Sewell","New Jersey","08080",{"type":142,"coordinates":519},[520,521],-75.14434,39.7665,{"lat":521,"lon":520},{"facility":524,"status":160,"city":525,"state":526,"zip":527,"country":139,"countryCode":140,"cosmosGeoPoint":528,"geoPoint":532,"contacts":40},"Finger Lakes Medical Research, PLLC - Site Number: 840155","Cortland","New York","13045",{"type":142,"coordinates":529},[530,531],-76.18048,42.60118,{"lat":531,"lon":530},{"facility":534,"status":160,"city":535,"state":526,"zip":536,"country":139,"countryCode":140,"cosmosGeoPoint":537,"geoPoint":541,"contacts":40},"Mid Hudson Medical Research, PLLC - Site Number: 840139","New Windsor","12553",{"type":142,"coordinates":538},[539,540],-74.02375,41.47676,{"lat":540,"lon":539},{"facility":543,"status":160,"city":526,"state":526,"zip":544,"country":139,"countryCode":140,"cosmosGeoPoint":545,"geoPoint":549,"contacts":40},"Icahn School of Medicine at Mount Sinai - Center for Advanced Medicine - Site Number: 840119","10029",{"type":142,"coordinates":546},[547,548],-74.00597,40.71427,{"lat":548,"lon":547},{"facility":551,"status":160,"city":552,"state":553,"zip":554,"country":139,"countryCode":140,"cosmosGeoPoint":555,"geoPoint":559,"contacts":40},"Allergy Partners of Western North Carolina - Site Number: 840131","Asheville","North Carolina","28801",{"type":142,"coordinates":556},[557,558],-82.55402,35.60095,{"lat":558,"lon":557},{"facility":561,"status":160,"city":562,"state":553,"zip":563,"country":139,"countryCode":140,"cosmosGeoPoint":564,"geoPoint":568,"contacts":40},"Clinical Research of Gastonia (CRG) - Site Number: 840160","Gastonia","28054-7489",{"type":142,"coordinates":565},[566,567],-81.1873,35.26208,{"lat":567,"lon":566},{"facility":570,"status":135,"city":571,"state":553,"zip":572,"country":139,"countryCode":140,"cosmosGeoPoint":573,"geoPoint":577,"contacts":40},"East Carolina University Physicians - Pulmonary and Critical Care Medicine - Site Number: 840142","Greenville","27834-2849",{"type":142,"coordinates":574},[575,576],-77.36635,35.61266,{"lat":576,"lon":575},{"facility":579,"status":160,"city":580,"state":581,"zip":582,"country":139,"countryCode":140,"cosmosGeoPoint":583,"geoPoint":587,"contacts":40},"NexGen Research - Site Number: 840154","Lima","Ohio","45801",{"type":142,"coordinates":584},[585,586],-84.10523,40.74255,{"lat":586,"lon":585},{"facility":589,"status":160,"city":590,"state":581,"zip":591,"country":139,"countryCode":140,"cosmosGeoPoint":592,"geoPoint":596,"contacts":40},"Toledo Institute of Clinical Research Inc - Site Number: 840105","Toledo","43617",{"type":142,"coordinates":593},[594,595],-83.55521,41.66394,{"lat":595,"lon":594},{"facility":598,"status":160,"city":599,"state":600,"zip":601,"country":139,"countryCode":140,"cosmosGeoPoint":602,"geoPoint":606,"contacts":40},"Allergy and Clinical Immunology Associates - Site Number: 840127","Pittsburgh","Pennsylvania","15241",{"type":142,"coordinates":603},[604,605],-79.99589,40.44062,{"lat":605,"lon":604},{"facility":608,"status":160,"city":609,"state":610,"zip":611,"country":139,"countryCode":140,"cosmosGeoPoint":612,"geoPoint":616,"contacts":40},"Clinical Research of Rock Hill - Site Number: 840115","Rock Hill","South Carolina","29732",{"type":142,"coordinates":613},[614,615],-81.02508,34.92487,{"lat":615,"lon":614},{"facility":618,"status":160,"city":619,"state":620,"zip":621,"country":139,"countryCode":140,"cosmosGeoPoint":622,"geoPoint":626,"contacts":40},"Allergy Associates, PA dba Allergy, Asthma and Sinus Center - Site Number: 840144","Tennessee City","Tennessee","30909",{"type":142,"coordinates":623},[624,625],-87.51474,36.09312,{"lat":625,"lon":624},{"facility":628,"status":160,"city":629,"state":630,"zip":631,"country":139,"countryCode":140,"cosmosGeoPoint":632,"geoPoint":636,"contacts":40},"Southwest Family Medicine Associates - Site Number: 840126","Dallas","Texas","75235",{"type":142,"coordinates":633},[634,635],-96.80667,32.78306,{"lat":635,"lon":634},{"facility":638,"status":160,"city":639,"state":630,"zip":640,"country":139,"countryCode":140,"cosmosGeoPoint":641,"geoPoint":645,"contacts":40},"El Paso Pulmonary Association (EPPA) - West El Paso - Site Number: 840108","El Paso","79902",{"type":142,"coordinates":642},[643,644],-106.48693,31.75872,{"lat":644,"lon":643},{"facility":647,"status":160,"city":648,"state":630,"zip":649,"country":139,"countryCode":140,"cosmosGeoPoint":650,"geoPoint":654,"contacts":40},"Lumi Research - Site Number: 840156","Houston","77090",{"type":142,"coordinates":651},[652,653],-95.36327,29.76328,{"lat":653,"lon":652},{"facility":656,"status":160,"city":648,"state":630,"zip":657,"country":139,"countryCode":140,"cosmosGeoPoint":658,"geoPoint":660,"contacts":40},"Pioneer Research Solutions - Site Number: 840104","77099",{"type":142,"coordinates":659},[652,653],{"lat":653,"lon":652},{"facility":662,"status":160,"city":663,"state":630,"zip":664,"country":139,"countryCode":140,"cosmosGeoPoint":665,"geoPoint":669,"contacts":40},"Lumi Research - Hurst - Site Number: 840164","Hurst","76054",{"type":142,"coordinates":666},[667,668],-97.17057,32.82346,{"lat":668,"lon":667},{"facility":671,"status":160,"city":672,"state":630,"zip":673,"country":139,"countryCode":140,"cosmosGeoPoint":674,"geoPoint":678,"contacts":40},"DM Clinical - Tomball - Site Number: 840130","Tomball","77081",{"type":142,"coordinates":675},[676,677],-95.61605,30.09716,{"lat":677,"lon":676},{"facility":680,"status":160,"city":681,"state":682,"zip":683,"country":139,"countryCode":140,"cosmosGeoPoint":684,"geoPoint":688,"contacts":40},"Bellingham Asthma, Allergy & Immunology Clinic - Site Number: 840138","Bellingham","Washington","98225",{"type":142,"coordinates":685},[686,687],-122.48822,48.75955,{"lat":687,"lon":686},{"facility":690,"status":135,"city":691,"state":692,"zip":693,"country":694,"countryCode":695,"cosmosGeoPoint":696,"geoPoint":700,"contacts":40},"Investigational Site Number: 124203","Calgary","Alberta","T3R 1W7","Canada","CA",{"type":142,"coordinates":697},[698,699],-114.08529,51.05011,{"lat":699,"lon":698},{"facility":702,"status":135,"city":703,"state":704,"zip":705,"country":694,"countryCode":695,"cosmosGeoPoint":706,"geoPoint":710,"contacts":40},"Investigational Site Number: 124201","Windsor","Ontario","N8X 2G1",{"type":142,"coordinates":707},[708,709],-83.01654,42.30008,{"lat":709,"lon":708},{"facility":712,"status":135,"city":713,"state":714,"zip":715,"country":694,"countryCode":695,"cosmosGeoPoint":716,"geoPoint":720,"contacts":40},"Investigational Site Number: 124204","Trois-Rivières","Quebec","G8T7A1",{"type":142,"coordinates":717},[718,719],-72.5477,46.34515,{"lat":719,"lon":718},{"facility":722,"status":135,"city":723,"state":724,"zip":725,"country":726,"countryCode":727,"cosmosGeoPoint":728,"geoPoint":732,"contacts":40},"Investigational Site Number: 250603","Brest","Brittany Region","29200","France","FR",{"type":142,"coordinates":729},[730,731],-4.48628,48.39029,{"lat":731,"lon":730},{"facility":734,"status":135,"city":735,"state":736,"zip":737,"country":738,"countryCode":739,"cosmosGeoPoint":740,"geoPoint":744,"contacts":40},"Investigational Site Number: 276502","Schleswig","Schleswig-Holstein","24837","Germany","DE",{"type":142,"coordinates":741},[742,743],9.56829,54.52021,{"lat":743,"lon":742},{"facility":746,"status":135,"city":747,"state":748,"zip":749,"country":750,"countryCode":751,"cosmosGeoPoint":40,"geoPoint":40,"contacts":40},"Investigational Site Number: 392705","Kitakyushu-Shi","Fukuoka","802-0083","Japan","JP",{"facility":753,"status":135,"city":754,"state":755,"zip":756,"country":750,"countryCode":751,"cosmosGeoPoint":757,"geoPoint":761,"contacts":40},"Investigational Site Number: 392702","Takamatsu","Kagawa-ken","761-8073",{"type":142,"coordinates":758},[759,760],134.05,34.33333,{"lat":760,"lon":759},{"facility":763,"status":135,"city":764,"state":765,"zip":766,"country":750,"countryCode":751,"cosmosGeoPoint":767,"geoPoint":771,"contacts":40},"Investigational Site Number: 392711","Saga","Saga-ken","849-8501",{"type":142,"coordinates":768},[769,770],130.3,33.23333,{"lat":770,"lon":769},{"type":773,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR",[775],{"name":776,"class":118},"Syneos Health","100635705","a-study-evaluating-disease-characteristics-and-outcomes-in-participants-with-asthma-in-routine-clinical-practice-100635705",false,"NCT07556159","A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice","A Hybrid Cross-sectional and Prospective Study to Assess Patient Characteristics, Disease Burden, Disease Control, Phenotypes, Endotypes, and Outcomes in a Real-world Setting in Patients With Asthma","AIRITY","Inclusion Criteria:\n\nApplicable for Part 1 participants:\n\n* Age 6 years and older, at the time of signing the informed consent\n* Physician diagnosis of asthma for at least 12 months\n* Existing treatment with low, medium, or high dose ICS and other asthma therapies as reflected in GINA 2-5 steps\n* Participant or legally authorized representative (where applicable) has consented to participate\n\nApplicable for Part 2 participants:\n\n* Age 18 years and older, at the time of signing the informed consent.\n* Physician diagnosis of asthma for at least 12 months\n* Existing treatment with low or medium ICS and other asthma therapies as reflected in GINA 2-4 steps\n* Participant or legally authorized representative (where applicable) has consented to participate\n* Participants must meet the criteria for at least one of the cohorts below:\n\nA) Asthma control cohorts\n\n1. ACQ-5 \\>= 1.5\n2. ACQ-5 \\\u003C 1.5 (B) Type-2 biomarker cohorts\n3. Elevated T2 biomarkers (B1: Type-2-high cohort)\n4. Low T2 biomarkers (B2: Type-2-low cohort)\n\nParticipants are excluded from the study if any of the following criteria apply (applicable for both Part 1 and Part 2 participants):\n\n* Current diagnosis of chronic obstructive pulmonary disease (COPD) or congestive heart failure\n* Participants with moderate\u002Fsevere cognitive impairment.\n* Participants with moderate\u002Fsevere cardiac disease.\n* Participants on immunosuppressive medication for a chronic condition.\n* Participation in other interventional and noninterventional clinical study (currently or in the past 3 months)\n\nThe above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.","ALL","6 Years",{"count":788,"type":789},2500,"ESTIMATED","24 Months","OBSERVATIONAL","The main aim of the study to describe the characteristics of participants with asthma across the spectrum of disease severity, including sociodemographic and clinical characteristics, treatment and disease burden, biomarkers, and both disease-specific and generic health-related quality of life.\n\nThe study consists of two parts: a cross-sectional study, and a prospective follow-up evaluate changes in disease trajectories in participants with asthma.",[794],"Asthma",[796,797,798],"Cross-Sectional","Multicenter","Inhaled Corticosteroids","2026-10-08",{"date":801,"type":802},"2026-10-09","ACTUAL",{"date":804,"type":802},"2026-04-01",{"date":806,"type":789},"2029-04-04",{"name":5,"class":6},71]