[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512621":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":31,"responsibleParty":47,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Echocardiography",null,"Patients participating in this study will undergo routine anesthetic and perioperative care with the addition of an echocardiography and non-invasive blood pressure (NIBP) cuff to measure blood pressure- in anywhere between 2.5 - 5 minute increments-before, immediately after anesthesia induction and after intubation for up to 20 minutes total.",[13],"Diagnostic Test: Echocardiography",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Echocardiography and non-invasive blood pressure (NIBP) cuff to measure blood pressure- in anywhere between 2.5 - 5 minute increments before, immediately after anesthesia induction and after intubation for up to 20 minute.",[9],[20],{"name":21,"affiliation":5,"role":22},"Anahita Dabo-Trubelja, MD","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","212-639-3279","daboa@mskcc.org",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":10},"Gregory Fischer, MD","212-639-2581",[32],{"facility":33,"status":34,"city":35,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Memorial Sloan Kettering Cancer Center (All protocol activites)","RECRUITING","New York","10065","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-74.00597,40.71427,{"lat":43,"lon":42},[46],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":10},{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100512621","a-study-of-changes-in-heart-function-and-blood-flow-in-people-receiving-anesthesia-100512621",false,"NCT05954832","A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia","Changes in Loading Conditions on Induction of General Anesthesia: Mechanisms of Post-Induction Hypotension (PIH)","Inclusion Criteria:\n\n* Adult patients ≥ 18 years of age requiring general anesthesia for surgery\n* Intubation required for anesthetic management \u002F surgery\n* Anticipated prep time before incision of 20 minutes\n* Baseline MAP \\>70mmHg\n\nExclusion Criteria:\n\n* History of coronary artery disease\n* History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)\n* History of peripheral artery occlusive disease\n* Beta-blocker use\n* Anti-hypertensive medication use\n* Patients with epidural, spinal, paravertebral, serratus blocks preoperatively\n* Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)\n* Emergency surgery","ALL","18 Years",{"count":59,"type":60},250,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.",[64],"Anesthesia",[66,67,9,68],"Changes in Heart Function","Changes in Blood Flow","23-079","2026-08-05",{"date":71,"type":72},"2026-08-10","ACTUAL",{"date":74,"type":72},"2023-07-13",{"date":76,"type":60},"2027-07",{"name":5,"class":6},1]