[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569515":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":31,"responsibleParty":49,"collaborators":11,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":11,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Home-Based Exercise Training","EXPERIMENTAL",null,[13],"Other: Exercise Training",{"label":15,"type":16,"description":11,"interventionNames":11},"Standard therapy (Standard of Care)","NO_INTERVENTION",[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":11},"Exercise Training","Patients will be recommended to exercise 3 days\u002Fweek, 20 minutes per session, for 12 weeks using personalized intervention determined by a consultation with a clinical exercise physiologist (CEP)",[9],[23],{"name":24,"affiliation":5,"role":25},"Stan Henkin, M.D.","PRINCIPAL_INVESTIGATOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":11,"email":30},"CONTACT","507-284-8612","Henkin.Stanislav@mayo.edu",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Mayo Clinic Rochester","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-92.4699,44.02163,{"lat":44,"lon":43},[47,48],{"name":24,"role":28,"phone":29,"phoneExt":11,"email":30},{"name":24,"role":25,"phone":11,"phoneExt":11,"email":11},{"type":25,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Stan Henkin","Associate Professor of Medicine","100569515","a-study-of-mobility-outcomes-in-post-pulmonary-embolic-disease-100569515",false,"NCT06695247","A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease","Mobility Outcomes in Post-Pulmonary Embolic Disease (MOPED): A Pilot Feasibility Prospective Randomized Trial","Inclusion Criteria:\n\nAcute intermediate-risk PE, defined as:\n\n* Intraluminal filling defect in segmental or larger vessels on computed tomography pulmonary angiography or high-probability ventilation\u002Fperfusion scan AND\n* Evidence of right ventricular enlargement by computed tomography (RV to LV ratio \\>1) or echocardiography; and\u002For right ventricular dysfunction by transthoracic echocardiography. These imaging characteristics must be in the setting of acute PE rather than explained by a prior chronic condition.\n\nAcute high-risk PE, defined as:\n\n* Intraluminal filling defect in segmental or larger vessels on computed tomography pulmonary angiography or high-probability ventilation\u002Fperfusion scan AND\n* Evidence of right ventricular enlargement by computed tomography (RV to LV ratio \\>1) or echocardiography; and\u002For right ventricular dysfunction by transthoracic echocardiography. These imaging characteristics must be in the setting of acute PE rather than explained by a prior chronic condition; AND\n* Hypotension (systolic blood pressure \\\u003C 90 mm Hg sustained for more than 15 minutes; or requiring vasopressors) or cardiogenic shock due to acute pulmonary embolism.\n\nExclusion Criteria:\n\n* Inability to ambulate independently, which is necessary to perform 6MWD (may be self-reported or as deemed by physical therapy during inpatient evaluation).\n* If patient requires supplemental oxygen during ambulation, this does not exclude patient from participation and will be noted during eCRF.\n* Prior history of pulmonary embolism\n* History of CTEPH or pulmonary arterial hypertension\n* Unable to read a questionnaire in English\n* Unable to return for baseline, 3- or 6-month follow-up visit\n* Pregnancy-associated pulmonary embolism\n* Life expectancy \\\u003C1 year based on comorbidities\n* Unable\u002Funwilling to provide informed written consent","ALL","18 Years","80 Years",{"count":63,"type":64},100,"ESTIMATED","INTERVENTIONAL",[67],"NA","The purpose of this study is to develop a unique structure and delivery of home-based exercise through multidisciplinary expertise of cardiovascular medicine specialists and cardiac physiologists using an Interactive Care Plan.",[70],"Pulmonary Embolism","2026-08-06",{"date":73,"type":74},"2026-08-10","ACTUAL",{"date":76,"type":74},"2025-07-14",{"date":78,"type":64},"2026-12",{"name":5,"class":6},1]