[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648896":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":57,"collaborators":21,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":21,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":21,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":21,"overallStatus":81,"whyStopped":21,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Supportive care (STRUM sessions)","EXPERIMENTAL","Patients receive a ukulele, tuner, and songbook and attend virtually delivered ukulele lessons over 30 minutes each, once weekly, for 10 weeks. Intervention sessions are structured with stair-stepping difficulty with each lesson concluding with learning a new song. Ten optional supplemental video-recorded lessons (approximately 15 minutes each) will be available for patients to view asynchronously and use for independent practice between weekly sessions. Patients are encouraged to practice their skills independently for at least 90 minutes per week. At the conclusion of the study, patients may attend an optional virtual \"Encore Concert Event\" remotely, featuring audio-video clips compiled from participants' lessons.",[13,14,15],"Other: Interview","Procedure: Music Therapy","Other: Survey Administration",[17,22,27],{"type":6,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"Interview","Ancillary studies",[9],null,{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":21},"PROCEDURE","Music Therapy","Attend STRUM sessions",[9],{"type":6,"name":28,"description":19,"armGroupLabels":29,"otherNames":21},"Survey Administration",[9],[31],{"name":32,"affiliation":5,"role":33},"C. Robert Bennett, PhD, RN","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":21,"email":39},"Robert Bennett, PhD, RN","CONTACT","480-301-4394","bennett.robert@mayo.edu",[41],{"facility":42,"status":21,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Mayo Clinic in Arizona","Scottsdale","Arizona","85259","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-111.89903,33.50921,{"lat":52,"lon":51},[55,56],{"name":36,"role":37,"phone":38,"phoneExt":21,"email":21},{"name":32,"role":33,"phone":21,"phoneExt":21,"email":21},{"type":58,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100648896","a-study-of-strengthening-teen-brain-resilience-using-music-during-cancer-treatment-100648896",false,"NCT07729384","A Study of Strengthening Teen Brain Resilience Using Music During Cancer Treatment","Strengthening Teen Brain Resilience Using Music (STRUM) During Cancer Treatment: A Pilot Feasibility Trial","Inclusion Criteria:\n\n* Aged 12-17 years at the time of enrollment\n* Receiving initial radiation therapy (RT) for cancer treatment with curative intent at the Mayo Clinic Arizona\n* Able to provide assent\n* Able to read and write in English\n* Have access to an electronic device with videoconferencing capability\n\nExclusion Criteria:\n\n* Less than three-month prognosis\n* Past history of RT\n* Self-reported visual, hearing, or cognitive impairment impeding the ability to complete the STRUM intervention\n* Prior receipt of ukulele or guitar lessons\n* Actively receiving musical instrument lessons","ALL","12 Years","17 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","This clinical trial tests the feasibility and acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment. Adolescents treated with radiation therapy for cancer often experience persistent cognitive deficits and reduced brain resilience or the ability to preserve cognitive and emotional functioning despite stressors. Musical instrument training has been shown to enhance memory, academic skills, and emotional well-being in youth. Although guitars are often the most preferred instrument, ukuleles offer greater accessibility due to their simplicity, affordability, and suitability for younger users. The STRUM intervention consists of virtual active music therapy ukulele lessons, which may be a feasible and acceptable way to improve radiation induced cognitive decline for adolescents undergoing radiation therapy for cancer treatment.",[77,78,79,80],"Childhood Hematopoietic and Lymphatic System Neoplasm","Childhood Malignant Solid Neoplasm","Hematopoietic and Lymphatic System Neoplasm","Malignant Solid Neoplasm","NOT_YET_RECRUITING","2026-07-22",{"date":84,"type":85},"2026-07-27","ACTUAL",{"date":87,"type":71},"2026-10-01",{"date":89,"type":71},"2028-11-01",{"name":5,"class":6},1]