[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649664":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":61,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acapella Device Group","EXPERIMENTAL","Participants in this arm will receive airway clearance therapy using the Acapella device. The device combines both positive expiratory pressure (PEP) and airway vibration to enhance mobilization of bronchial secretions. Patients will be trained to perform standardized breathing techniques using the device. The intervention will be administered twice daily for 7 days, under supervision during hospital stay or as per protocol guidelines. Standard post-lobectomy care will be continued alongside the intervention.",[13],"Device: Acapella Device Therapy (Experimental Arm 1):",{"label":15,"type":16,"description":17,"interventionNames":18},"Flutter Device Group","ACTIVE_COMPARATOR","Participants in this arm will receive airway clearance therapy using the Flutter device, which generates oscillatory positive expiratory pressure to loosen and mobilize airway secretions. Patients will be instructed in proper usage technique to ensure effective airflow oscillation during exhalation. The intervention will be performed twice daily for 7 days, following a standardized protocol similar to the Acapella group. Routine post-operative care will be provided in addition to the intervention.",[19],"Device: Flutter Device Therapy (Experimental Arm 2):",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Acapella Device Therapy (Experimental Arm 1):","1\\. Acapella Device Therapy (Experimental Arm 1): Participants will use the Acapella device, which provides a combination of oscillating positive expiratory pressure (OPEP) and airway vibration to facilitate mucus clearance. Patients will be trained in proper technique and will perform the intervention twice daily for 7 days. Each session will follow a standardized protocol to ensure consistency in breathing pattern and device usage.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Flutter Device Therapy (Experimental Arm 2):","Flutter Device Therapy (Experimental Arm 2):\n\nParticipants will use the Flutter device, which generates oscillating positive expiratory pressure during exhalation to mobilize bronchial secretions. Patients will be instructed in correct positioning and breathing technique. The intervention will also be administered twice daily for 7 days using a standardized protocol.",[15],[32],{"name":33,"affiliation":5,"role":34},"Tanzeela Nazir, MSCPPT","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Humera Ayub, MSCPPT","CONTACT","+923045938096","humera.ayub@riphah.edu.pk",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Lahore","Punjab Province","55000","Pakistan","PK",{"type":50,"coordinates":51},"Point",[52,53],74.35071,31.558,{"lat":53,"lon":52},[56,59,60],{"name":33,"role":38,"phone":57,"phoneExt":26,"email":58},"+92-300-0334782","tanzeela.nazir@riphah.edu",{"name":37,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":62,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100649664","acapella-vs-flutter-devices-for-improving-breathing-and-lung-function-after-lobectomy-100649664",false,"NCT07737093","Acapella vs Flutter Devices for Improving Breathing and Lung Function After Lobectomy","Comparative Effects of Acapella and Flutter Devices on Secretion Clearance, Dyspnea, Arterial Blood Gases, and Lung Function Test in Post-Lobectomy Patients","Inclusion Criteria:\n\n* Patients aged 35 to 54 years\n* Both male and female patients\n* Patients who have undergone lobectomy surgery\n* Hemodynamically stable patients\n* Patients with adequate respiratory function (able to maintain oxygenation)\n* Patients 48 hours post-surgery\n* Patients who provide written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Hemodynamically unstable patients\n* Patients within less than 48 hours post-surgery\n* Presence of pneumothorax or air leak complications\n* Patients with recent major trauma or additional surgery\n* Patients with unstable cardiac conditions\n* Patients with massive hemoptysis\n* Patients unable to cooperate or perform breathing exercises with devices\n* Any contraindication to airway clearance techniques as judged by the clinician","ALL","35 Years","54 Years",{"count":74,"type":75},28,"ESTIMATED","INTERVENTIONAL",[78],"NA","Lobectomy patients frequently experience postoperative respiratory complications such as secretion retention, dyspnea, impaired gas exchange, and reduced lung function, which can delay recovery. Oscillatory Positive Expiratory Pressure (OPEP) devices such as Acapella and Flutter are commonly used to improve airway clearance and pulmonary function. This study aims to compare the effects of Acapella and Flutter devices on secretion clearance, dyspnea, arterial blood gases, and lung function in post-lobectomy patients.",[81],"Lobotomy Syndrome",[83],"Acapella device Flutter device Post-lobectomy patients Secretion clearance Dyspnea Arterial blood gases Lung function Chest physiotherapy","2026-07-27",{"date":86,"type":87},"2026-07-30","ACTUAL",{"date":89,"type":87},"2026-06-20",{"date":91,"type":75},"2026-12-15",{"name":5,"class":6},1]