[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649001":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":26,"responsibleParty":41,"collaborators":43,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":26,"enrollmentInfo":56,"targetDuration":26,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"University of Leicester","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard care arm stress CMR","ACTIVE_COMPARATOR","Participants randomised to the standard care arm will undergo a standard stress cardiovascular magnetic resonance (CMR) scan",[13],"Procedure: Standard stress cardiovascular magnetic resonance (CMR)",{"label":15,"type":16,"description":17,"interventionNames":18},"Accelerated stress CMR","EXPERIMENTAL","Participants randomised to the accelerated arm will undergo an accelerated stress cardiovascular magnetic resonance (CMR) scan.",[19],"Procedure: Accelerated stress cardiovascular magnetic resonance (CMR)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Standard stress cardiovascular magnetic resonance (CMR)","Standard stress cardiovascular magnetic resonance (CMR) scan performed according to the study protocol.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Accelerated stress cardiovascular magnetic resonance (CMR)","Accelerated stress cardiovascular magnetic resonance (CMR) scan performed according to the study protocol.",[15],[32],{"name":33,"affiliation":5,"role":34},"Ranjit Arnold","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Fuad Fananapazir","CONTACT","+447763941607","accelerate@leicester.ac.uk",{"type":42,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[44],{"name":45,"class":6},"University of Glasgow","100649001","accelerate-cmr-for-coronary-artery-disease-detection-100649001",false,"NCT07729111","ACCELERATE-CMR for Coronary Artery Disease Detection","ACCELERATE-CMR: Accelerated Cardiovascular Magnetic Resonance for the Detection of Coronary Artery Disease - a Randomised Controlled Trial","ACCELERATE-CMR","Inclusion criteria\n\n* patients \\>18 years of age referred for routine clinical stress CMR:\n* A) with chest pain or angina equivalent OR\n\n  o B) with heart failure\u002Fsuspected heart failure and referred for diagnosis of suspected CAD or evaluation of heart failure aetiology\n* Willing and able to consent to participate in the trial\n\nExclusion criteria\n\n* standard exclusion criteria for clinical stress CMR i.e.:\n\n  * absolute contraindications to CMR (non-conditional cardiac implantable electronic devices, metallic implants\u002Fforeign bodies),\n  * contraindications to adenosine (severe pulmonary disease, sinus-node\u002Fhigh-grade atrioventricular disease)\n  * severe kidney dysfunction (estimated glomerular filtration rate \\[eGFR\\] \\\u003C30ml\u002Fmin\u002F1.73m2)\n  * uncontrolled arrhythmia or unstable chest pain\n  * severe claustrophobia\n* previous invasive coronary angiography (within 12 months) with normal angiographic assessment and referred for CMR diagnosis of CMD","ALL","18 Years",{"count":57,"type":58},2022,"ESTIMATED","INTERVENTIONAL",[61],"NA","Coronary heart disease occurs when the blood vessels that supply the heart become narrowed or blocked. It is a leading cause of illness and death in the UK. Accurate diagnosis is important because effective treatments are available, but current tests are invasive, uncomfortable, and carry some risks.\n\nCardiovascular magnetic resonance (CMR), also known as a heart MRI scan, is a safe and accurate test for diagnosing coronary heart disease. However, access to CMR is limited because standard scans take around 45 to 50 minutes, restricting the number of patients who can be scanned.\n\nResearchers have developed a faster CMR scan that takes only 15 to 20 minutes. Previous studies suggest that this shorter scan provides similar accuracy to the standard scan while improving patient comfort.\n\nThis study will recruit 2022 adults with suspected coronary heart disease from hospitals in the UK. Participants will be randomly assigned to receive either the standard CMR scan or the faster CMR scan.\n\nThe study will compare whether the accelerated scan provides similar clinical outcomes to the standard scan and whether patients prefer it. If successful, the accelerated scan could increase access to CMR by allowing more patients to be scanned each day, and enabling more efficient use of NHS resources.",[64],"CAD - Coronary Artery Disease",[66],"MRI","NOT_YET_RECRUITING","2026-07-22",{"date":70,"type":71},"2026-07-27","ACTUAL",{"date":73,"type":58},"2026-09",{"date":75,"type":58},"2031-05",{"name":5,"class":6}]