[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651111":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":30,"locations":10,"responsibleParty":36,"collaborators":10,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":10,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":10,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":10,"overallStatus":55,"whyStopped":10,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":10},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Paired 3D-EIT and 4D-CT Assessment Cohort",null,"This single cohort will include approximately 50 adults, including healthy volunteers and hospitalized patients, who are able to undergo synchronous 3D-EIT and 4D-CT data acquisition. Regional lung ventilation measurements obtained by the two methods during the same breathing cycle will be compared for agreement and accuracy. Participants will not be assigned to different study groups, and the research EIT results will not be used to direct clinical treatment.",[13,14],"Device: Three-Dimensional Electrical Impedance Tomography","Diagnostic Test: Dynamic Chest Computed Tomography",[16,23],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DEVICE","Three-Dimensional Electrical Impedance Tomography","Regional lung ventilation data will be collected using a chest electrical impedance tomography system (V200-S). Electrical impedance changes in the chest will be measured continuously and reconstructed to assess three-dimensional regional ventilation distribution. EIT data will be acquired synchronously with dynamic computed tomography data and will be used for research analysis only. The research EIT results will not directly guide clinical treatment decisions.",[9],[22],"3D-EIT",{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DIAGNOSTIC_TEST","Dynamic Chest Computed Tomography","Dynamic chest computed tomography data will be acquired using an X-ray computed tomography system (uCT 610 Sim) during one or more breathing cycles. The images will be reconstructed and analyzed to quantify changes in regional lung air volume and ventilation distribution. The 4D-CT measurements will serve as the reference method for comparison with 3D-EIT measurements.",[9],[29],"4D-CT",[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Yuxian Wang","CONTACT","+86 021 6404 1990","wang.yuxian@zs-hospital.sh.cn",{"type":37,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100651111","accuracy-of-3d-electrical-impedance-tomography-for-assessing-lung-ventilation-100651111",false,"NCT07756086","Accuracy of 3D Electrical Impedance Tomography for Assessing Lung Ventilation","Accuracy of Three-Dimensional Electrical Impedance Tomography for Assessing Dynamic Regional Lung Ventilation Validated by Four-Dimensional CT: A Prospective Observational Study","Inclusion Criteria:\n\n* Age 18 years or older.\n* Healthy volunteers or patients in the intensive care unit for whom CT imaging is considered necessary based on the treating physician's clinical judgment.\n* Able to cooperate with or undergo simultaneous 4D-CT and 3D-EIT monitoring.\n* Able to provide written informed consent personally or through a legally authorized representative, as applicable.\n\nExclusion Criteria:\n\n* Unable to tolerate or having a contraindication to 4D-CT examination, including pregnancy or severe respiratory distress.\n* Extensive chest skin injury or infection, or any condition preventing placement of the EIT electrode belt.\n* Body size or chest deformity that may substantially limit the quality of EIT or CT data, including chest circumference outside the compatible range of the EIT device.\n* Presence of an implanted electronic device that may interfere with EIT signals, such as a cardiac pacemaker.\n* Unable to complete simultaneous 4D-CT and 3D-EIT monitoring because of significant motion, persistent coughing, poor cooperation, or other technical or clinical reasons.\n* Any other condition that, in the investigator's judgment, makes the individual unsuitable for participation in the study.",true,"ALL","18 Years",{"count":49,"type":50},50,"ESTIMATED","OBSERVATIONAL","This prospective observational study will evaluate how accurately three-dimensional electrical impedance tomography (3D-EIT) measures the distribution of air in the lungs during breathing when compared with four-dimensional computed tomography (4D-CT).\n\n3D-EIT is a noninvasive, radiation-free imaging method that measures changes in electrical impedance across the chest and can provide continuous information about regional lung ventilation. In this study, 4D-CT will be used as the reference method because it can provide detailed images of changes in the lungs throughout the breathing cycle.\n\nApproximately 50 adults, including healthy volunteers and hospitalized patients who are able to undergo both examinations, will be enrolled at a single center. EIT and CT data will be collected at the same time during stable breathing. Researchers will compare the two methods to determine how closely their measurements of ventilation in different lung regions agree. The study will also explore whether EIT can detect changes in regional ventilation under different breathing conditions.\n\nThe study will not use the research EIT results to make clinical treatment decisions. The findings may support the future use of EIT as a noninvasive, radiation-free method for monitoring regional lung ventilation.",[54],"Pulmonary Ventilation","NOT_YET_RECRUITING","2026-08-04",{"date":58,"type":59},"2026-08-10","ACTUAL",{"date":61,"type":50},"2026-09-01",{"date":63,"type":50},"2027-07-01",{"name":5,"class":6}]