[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652163":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":51,"centralContacts":56,"locations":61,"responsibleParty":76,"collaborators":79,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":50,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":50,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":104,"overallStatus":112,"whyStopped":50,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Taipei City Hospital","OTHER_GOV",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Acupoint catgut embedding plus active laser acupuncture","EXPERIMENTAL","Participants receive acupoint catgut embedding at 15 acupoints (25 insertions) once every 2 weeks for 6 sessions, at Weeks 0, 2, 4, 6, 8, and 10. Immediately before each embedding session, active 810 nm laser acupuncture is applied to the same acupoints for 10 seconds per point, delivering 5 joules per point. All participants also receive standardized dietary and exercise counseling.",[13,14,15],"Procedure: Acupoint catgut embedding","Device: Active laser acupuncture","Behavioral: Dietary and exercise counseling",{"label":17,"type":18,"description":19,"interventionNames":20},"Acupoint catgut embedding plus sham laser acupuncture","SHAM_COMPARATOR","Participants receive exactly the same acupoint catgut embedding regimen at the same 15 acupoints on the same schedule. Immediately before each embedding session, a sham laser pen is applied to the same acupoints for the same duration. The sham pen is identical in appearance, indicator light, and operating sound, but its laser module is disconnected and actual output is 0 milliwatts. All participants also receive standardized dietary and exercise counseling.",[13,21,15],"Device: Sham laser acupuncture",[23,31,39,45],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","Acupoint catgut embedding","Poliglecaprone 25 absorbable suture, in segments of approximately 1 to 1.5 cm, is implanted subcutaneously at acupoints with a disposable 22-gauge or 24-gauge embedding needle. Fifteen acupoints are treated at each session, giving 25 insertions in total: ST25, CV12, ST24, ST21, CV10, CV9, SP15, CV6, CV4, ST28, ST27, and GB26 on the abdomen, and ST40, ST36, and SP9 on the limbs, with bilateral points treated on both sides. Sessions occur once every 2 weeks at Weeks 0, 2, 4, 6, 8, and 10.",[9,17],[29,30],"Thread embedding acupuncture","Catgut implantation at acupoint",{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DEVICE","Active laser acupuncture","An RJ Laser Pen with a gallium aluminium arsenide semiconductor laser diode, wavelength 810 nm, maximum output 500 milliwatts, continuous wave, is applied with a contact probe. Irradiation is delivered to the same acupoint sites that receive embedding, for 10 seconds per site, delivering 5 joules per site at approximately 20 joules per square centimeter, immediately before the acupoint embedding at each of the 6 sessions. Safety goggles are worn during irradiation.",[9],[37,38],"Low-level laser therapy","Photobiomodulation",{"type":32,"name":40,"description":41,"armGroupLabels":42,"otherNames":43},"Sham laser acupuncture","A dedicated sham laser pen supplied by the manufacturer is applied to the same acupoints, for the same duration, and on the same schedule as the active laser. The sham pen is identical to the active pen in housing, red indicator light, and operating sound, but its laser module is disconnected so that actual output is 0 milliwatts.",[17],[44],"Placebo laser",{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":50},"BEHAVIORAL","Dietary and exercise counseling","Standardized dietary counseling is given at baseline and at Week 6, advising a daily energy intake approximately 500 kilocalories below requirement without a prescribed menu, together with a recommendation of at least 150 minutes per week of moderate-intensity aerobic exercise. Participants complete a weekly diet and exercise log.",[9,17],null,[52],{"name":53,"affiliation":54,"role":55},"Chia-Lin Lin, MD","Taipei City Hospital, Renai Branch","PRINCIPAL_INVESTIGATOR",[57],{"name":53,"role":58,"phone":59,"phoneExt":50,"email":60},"CONTACT","886-905-211-208","DBB10@tpech.gov.tw",[62],{"facility":54,"status":50,"city":63,"state":50,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Taipei","106","Taiwan","TW",{"type":68,"coordinates":69},"Point",[70,71],121.52639,25.05306,{"lat":71,"lon":70},[74,75],{"name":53,"role":58,"phone":59,"phoneExt":50,"email":60},{"name":53,"role":55,"phone":50,"phoneExt":50,"email":50},{"type":55,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":50,"oldOrganization":50},"Chia-Lin Lin","Attending Physician, Department of Chinese Medicine",[80],{"name":81,"class":82},"Taipei City Government Department of Health","UNKNOWN","100652163","acupoint-catgut-embedding-with-laser-acupuncture-for-weight-loss-in-adults-with-obesity-100652163",false,"NCT07770893","Acupoint Catgut Embedding With Laser Acupuncture for Weight Loss in Adults With Obesity","Acupoint Embedding Combined With Laser Acupuncture for Obesity: A Randomized, Double-Blind, Sham Laser-Controlled Trial Evaluating Anthropometric, Biochemical, and Hemodynamic Outcomes","Inclusion Criteria:\n\n* Age 20 to 65 years\n* Body mass index of 27 kg\u002Fm\\^2 or greater, or body mass index of 24 kg\u002Fm\\^2 or greater together with a waist circumference of 90 cm or greater in men or 80 cm or greater in women\n* Able to fully understand the informed consent document and willing to give written informed consent\n* No use of weight-loss medication and no other weight-reduction treatment in the 3 months before enrollment\n* Willing to follow the dietary and exercise advice given during the trial\n\nExclusion Criteria:\n\n* Current use of medication that may affect body weight, including corticosteroids, antipsychotics, insulin, or glucagon-like peptide-1 (GLP-1) receptor agonists\n* Known secondary cause of obesity, such as hypothyroidism, Cushing syndrome, or pituitary disease\n* Severe cardiovascular, hepatic, or renal disease, or poorly controlled diabetes defined as glycated hemoglobin (HbA1c) above 9 percent\n* Currently pregnant, breastfeeding, or planning pregnancy within 6 months\n* Bariatric surgery within the previous 6 months\n* Known allergy to absorbable suture material\n* Skin infection at the embedding sites, keloid tendency, or coagulation disorder\n* Implanted cardiac pacemaker or other electromagnetic implant\n* Known photosensitivity disorder or current use of photosensitizing medication","ALL","20 Years","65 Years",{"count":94,"type":95},120,"ESTIMATED","INTERVENTIONAL",[98],"NA","Acupoint catgut embedding and laser acupuncture have each been studied as treatments for obesity in adults, but the two have not been evaluated in combination, and few trials have measured anthropometric, biochemical, and blood pressure outcomes together.\n\nThis single-center randomized sham-controlled trial plans to enroll 120 adults aged 20 to 65 years with obesity. All participants receive the same acupoint catgut embedding with poliglecaprone 25 absorbable suture at 15 acupoints, comprising 25 insertions, once every 2 weeks for 6 sessions over 12 weeks. Participants are randomly assigned in a 1:1 ratio to receive, immediately before each embedding session, either active 810 nm laser acupuncture or sham laser acupuncture delivered with a device that is identical in appearance, indicator light, and operating sound but emits no therapeutic energy. Both groups also receive standardized dietary and exercise counseling.\n\nBecause the acupoint embedding regimen is identical in both groups and the groups differ only in whether the laser emits energy, the comparison estimates the incremental effect of laser acupuncture added to acupoint embedding. Participants are treated for 12 weeks and then followed for a further 12 weeks, to Week 24.",[101,102,103],"Obesity","Obesity, Abdominal","Overweight",[105,106,107,108,109,110,111],"acupoint catgut embedding","thread embedding acupuncture","laser acupuncture","photobiomodulation","poliglecaprone 25","traditional Chinese medicine","weight loss","NOT_YET_RECRUITING","2026-08-12",{"date":115,"type":116},"2026-08-18","ACTUAL",{"date":118,"type":95},"2026-09",{"date":120,"type":95},"2028-12",{"name":5,"class":6},1]