[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649273":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":51,"collaborators":26,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":26,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":26,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Tainan Hospital, Ministry of Health and Welfare","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise Combined with Acupoint Stimulation","EXPERIMENTAL","Participants receive a 12-week multimodal intervention, including the Vivifrail exercise program (daily, 45-60 minutes) and personalized daytime and sleep acupoint stimulation (2-3 times daily).",[13,14],"Behavioral: Vivifrail Exercise Program","Other: Acupoint Stimulation",{"label":16,"type":17,"description":18,"interventionNames":19},"Exercise Training Only","ACTIVE_COMPARATOR","Participants receive the 12-week Vivifrail exercise program and sleep hygiene education, without any acupoint stimulation.",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Vivifrail Exercise Program","A 12-week home-based multimodal exercise program including daily walking, upper limb resistance training, balance exercises, and flexibility training, tailored to pre-frail older adults.",[9,16],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Acupoint Stimulation","Daily home-based acupoint self-massage (2-3 times per day, 3-5 minutes per point) targeting specific meridians (including Spleen, Stomach, and Bladder meridians) to alleviate fatigue and promote sleep quality.",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yu-Ching Hsu, MD","CONTACT","+886-6-2202121","tnhpcm2017@gmail.com",[38],{"facility":5,"status":39,"city":40,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Tainan","Taiwan","TW",{"type":44,"coordinates":45},"Point",[46,47],120.21333,22.99083,{"lat":47,"lon":46},[50],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Yu-Ching HSU","Attending Physician","100649273","acupoint-stimulation-and-exercise-for-taiwanese-pre-frail-older-adults-100649273",false,"NCT07732530","Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults","Exploring the Associations Among Frailty, Daily Physical Activity, Sleep, and Traditional Chinese Medicine Constitution in Taiwanese Older Adults, and Evaluating the Effects of Acupoint Stimulation Interventions","Inclusion Criteria:\n\n1. Individuals who are capable of undergoing frailty assessments.\n2. Individuals who possess effective communication skills.\n3. Aged 50 years or older.\n4. Willing to provide written informed consent, keep a 7-day sleep diary, and complete related questionnaires.\n5. Identified as pre-frail (frailty score of 1-2 points) according to the frailty phenotype criteria for the clinical trial phase.\n\nExclusion Criteria:\n\n1\\. Individuals who are unwilling or unable to wear an actigraph (wrist monitor) or undergo physical measurements.","ALL","50 Years",{"count":65,"type":66},30,"ESTIMATED","INTERVENTIONAL",[69],"NA","This study aims to explore the relationships between frailty, daily physical activity, sleep quality, and Traditional Chinese Medicine (TCM) constitutions among older adults in Taiwan. In the trial phase, a randomized controlled trial will be conducted specifically for pre-frail older adults. Participants will be randomly assigned to either the exercise training group (Vivifrail program) or the integrated group combining exercise with daytime and sleep-improving acupoint stimulation. The study evaluates the combined efficacy of these non-invasive interventions on reducing frailty severity, improving sleep, and enhancing daily physical functions.",[72,73,74],"Frailty","Sleep Quality","Aging","2026-08-04",{"date":77,"type":78},"2026-08-07","ACTUAL",{"date":80,"type":78},"2025-06-03",{"date":82,"type":66},"2027-12-31",{"name":5,"class":6},1]