[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656150":3},{"organization":4,"outcomesModule":7,"designInfo":36,"detailedDescription":42,"studyPopulation":35,"armGroups":43,"interventions":50,"overallOfficials":35,"centralContacts":55,"locations":61,"responsibleParty":73,"collaborators":35,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":86,"minAge":87,"maxAge":35,"enrollmentInfo":88,"targetDuration":35,"studyType":91,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":104,"whyStopped":35,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Karabuk University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":35},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Xiphoid-Level Chest Expansion","Chest expansion will be measured at the xiphoid\u002Fepigastric level using a non-elastic measuring tape. The difference between chest circumference at maximal inspiration and maximal expiration will be calculated in centimeters. Measurements will be repeated using the same anatomical landmarks and standardized participant position across assessment time points.","Baseline (T0), immediately after the first treatment session (T1), at the end of 6 weeks of treatment (T2), 1 month after treatment (T3), and 3 months after treatment (T4).",[14,17,20,23,26,29,32],{"measure":15,"description":16,"timeFrame":12},"Change in Forced Vital Capacity (FVC)","Forced vital capacity will be assessed using spirometry and recorded in liters. Participants will perform repeated acceptable forced expiratory maneuvers according to the standardized measurement procedure, and the highest acceptable FVC value will be used for analysis.",{"measure":18,"description":19,"timeFrame":12},"Change in Forced Expiratory Volume in 1 Second (FEV1)","Forced expiratory volume in 1 second will be assessed using spirometry and recorded in liters. Participants will perform repeated acceptable forced expiratory maneuvers, and the highest acceptable FEV1 value will be used for analysis.",{"measure":21,"description":22,"timeFrame":12},"Change in FEV1\u002FFVC Ratio","The FEV1\u002FFVC ratio will be calculated automatically by the spirometry device from acceptable forced expiratory maneuvers and recorded as a percentage.",{"measure":24,"description":25,"timeFrame":12},"Change in Peak Expiratory Flow (PEF)","Peak expiratory flow will be assessed during standardized spirometry maneuvers. The highest technically acceptable PEF value will be recorded and used for analysis, expressed according to the spirometry device output.",{"measure":27,"description":28,"timeFrame":12},"Change in Peak Cough Flow (PCF)","Peak cough flow will be assessed using a portable peak flow meter and recorded in liters per minute. Participants will perform at least three technically appropriate voluntary cough maneuvers after a deep inspiration, and the highest technically acceptable PCF value will be used for analysis.",{"measure":30,"description":31,"timeFrame":12},"Change in Axillary-Level Chest Expansion","Chest expansion at the axillary level will be measured using a non-elastic measuring tape positioned approximately at the level of the third rib. The difference between chest circumference at maximal inspiration and maximal expiration will be calculated in centimeters. The same participant position and anatomical landmarks will be used across all assessment time points",{"measure":33,"description":34,"timeFrame":12},"Change in Subcostal-Level Chest Expansion","Chest expansion at the subcostal level will be measured using a non-elastic measuring tape. The difference between chest circumference at maximal inspiration and maximal expiration will be calculated in centimeters. The same standardized participant position and anatomical landmarks will be used at each assessment time point.",null,{"allocation":37,"interventionModel":38,"interventionModelDescription":35,"primaryPurpose":39,"observationalModel":35,"timePerspective":35,"maskingInfo":40},"NA","SINGLE_GROUP","BASIC_SCIENCE",{"masking":41,"maskingDescription":35,"whoMasked":35},"NONE","Myofascial release therapy is a manual therapy approach intended to reduce restrictions in fascial tissues and improve tissue mobility. Fascial structures surrounding the thorax, neck, shoulder, and upper extremity may contribute to chest wall mechanics and movements associated with breathing.\n\nPrevious studies have mainly focused on immediate or short-term responses to myofascial release techniques, while evidence regarding cumulative and sustained effects remains limited. Therefore, this prospective single-group interventional study is designed to evaluate both the immediate response to the first treatment session and the effects of repeated treatment over time.\n\nIntegrated myofascial release therapy will be applied to fascial structures associated with the upper extremity, neck-shoulder region, and pectoral\u002Fanterior chest region. Treatment will be administered twice weekly for 6 weeks, for a total of 12 sessions.\n\nAssessments will be conducted at five time points: before treatment (T0), immediately after the first treatment session (T1), at the end of the 6-week treatment period (T2), 1 month after treatment (T3), and 3 months after treatment (T4).\n\nPulmonary function will be evaluated using spirometry, including forced vital capacity, forced expiratory volume in 1 second, the FEV1\u002FFVC ratio, and peak expiratory flow. Cough strength will be assessed using peak cough flow. Thoracic mobility will be evaluated using chest expansion measurements at the axillary, xiphoid\u002Fepigastric, and subcostal levels.\n\nThe study is intended to distinguish the acute response to a single session from the cumulative effect of repeated treatment and the persistence of any observed effects after treatment has ended.",[44],{"label":45,"type":46,"description":47,"interventionNames":48},"Integrated Myofascial Release Therapy","EXPERIMENTAL","Participants in this arm will receive integrated myofascial release therapy twice weekly for 6 weeks, for a total of 12 sessions. Each session will last approximately 20-30 minutes. The intervention will include single arm pull, lateral neck-shoulder myofascial release, and pectoral-anterior chest cross-hand release techniques applied in a standardized sequence.",[49],"Other: Other",[51],{"type":6,"name":52,"description":53,"armGroupLabels":54,"otherNames":35},"Other","Integrated myofascial release therapy will be administered twice weekly for 6 weeks, for a total of 12 sessions. Each session will last approximately 20-30 minutes. The intervention will include single arm pull, lateral neck-shoulder myofascial release, and pectoral-anterior chest cross-hand release techniques. Techniques will be applied using slow, low-intensity, pain-free manual contact while following tissue resistance and release. The sequence and target regions will be standardized across sessions.",[45],[56],{"name":57,"role":58,"phone":59,"phoneExt":35,"email":60},"Ece Acar, Assist Prof","CONTACT","05457925035","acarkosanece@gmail.com",[62],{"facility":5,"status":35,"city":63,"state":64,"zip":65,"country":66,"countryCode":35,"cosmosGeoPoint":67,"geoPoint":72,"contacts":35},"Karabük","Karabük Province","78050","Turkey (Türkiye)",{"type":68,"coordinates":69},"Point",[70,71],32.62768,41.20488,{"lat":71,"lon":70},{"type":74,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","Ece ACAR","Assist Prof","100656150","acute-and-long-term-effects-of-integrated-myofascial-release-therapy-on-respiratory-function-in-healthy-adults-100656150",false,"NCT07822139","Acute and Long-Term Effects of Integrated Myofascial Release Therapy on Respiratory Function in Healthy Adults","Acute and Long-Term Effects of Integrated Myofascial Release Therapy on Pulmonary Function, Thoracic Mobility, and Cough Strength in Healthy Adults","EMGT-RESP","Inclusion Criteria:\n\n* Age 18 years or older.\n* Ability to communicate in Turkish.\n* Voluntary agreement to participate in the study.\n* Ability to attend the scheduled assessment and treatment sessions regularly.\n\nExclusion Criteria:\n\n* Asthma, clinically significant dyspnea, or chronic pulmonary disease.\n* Influenza, COVID-19, or another acute respiratory tract infection within the previous 6 weeks that may affect respiratory function.\n* Recent surgery involving the neck, shoulder, or thoracic region.\n* History of rib fracture or an acute musculoskeletal condition that would make manual therapy inappropriate.\n* Serious cardiovascular, neurological, or systemic disease that could prevent safe participation in the assessments.",true,"ALL","18 Years",{"count":89,"type":90},40,"ESTIMATED","INTERVENTIONAL",[37],"This study will investigate the immediate and longer-term effects of integrated myofascial release therapy on breathing-related outcomes in healthy adults.\n\nParticipants will receive integrated myofascial release therapy twice a week for 6 weeks, for a total of 12 treatment sessions. Assessments will be performed before treatment, immediately after the first treatment session, at the end of the 6-week treatment period, and 1 month and 3 months after treatment.\n\nThe study will evaluate pulmonary function, cough strength, and chest mobility. The aim is to determine both the immediate response to a single treatment session and whether repeated treatment produces effects that are maintained during follow-up.",[95],"Respiratory Function",[45,97,98,99,100,101,102,103],"Myofascial Release","Manual Therapy","Pulmonary Function","Thoracic Mobility","Chest Expansion","Peak Cough Flow","Healthy Adults","NOT_YET_RECRUITING","2026-09-10",{"date":107,"type":108},"2026-09-16","ACTUAL",{"date":110,"type":90},"2026-10-16",{"date":112,"type":90},"2027-06-29",{"name":5,"class":6},1]