[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648124":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":40,"locations":46,"responsibleParty":68,"collaborators":71,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":23,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":23,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":23,"overallStatus":49,"whyStopped":23,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"University of Milan","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All Interventions (Crossover)","EXPERIMENTAL","Participants receive all five test products in a randomized crossover design. The order of administration is randomized, and each product is provided in an amount adjusted to deliver a standardized lipid dose of 0.5 g\u002Fkg of body weight. A washout period of at least 7 days is applied between interventions.",[13,14,15,16,17],"Other: MCT Beverage","Other: LCT Beverage","Other: Synthetic MCT Powder","Other: Natural MCT Powder","Other: MCT Biscuit",[19,24,28,32,36],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"MCT Beverage","Beverage containing medium-chain triglycerides (MCTs). Administered in a quantity adjusted to provide a lipid dose of 0.5 g\u002Fkg of body weight.",[9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"LCT Beverage","Beverage containing long-chain triglycerides (LCTs). Administered in a quantity adjusted to provide a lipid dose of 0.5 g\u002Fkg of body weight.",[9],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":23},"Synthetic MCT Powder","Powder formulation containing synthetic medium-chain triglycerides (MCTs) composed of C8 and C10 fatty acids, reconstituted in water before consumption. Administered in a quantity adjusted to provide a lipid dose of 0.5 g\u002Fkg of body weight.",[9],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"Natural MCT Powder","Powder formulation containing medium-chain triglycerides (MCTs) derived from coconut oil (containing fatty acids from C8 to C12), reconstituted in water before consumption. Administered to provide a lipid dose of 0.5 g\u002Fkg of body weight",[9],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":23},"MCT Biscuit","Biscuit containing medium-chain triglycerides (MCTs) derived from coconut oil. Administered in a quantity adjusted to provide a lipid dose of 0.5 g\u002Fkg of body weight.",[9],[41],{"name":42,"role":43,"phone":44,"phoneExt":23,"email":45},"Alessandro Leone","CONTACT","00390250316652","alessandro.leone1@unimi.it",[47],{"facility":48,"status":49,"city":50,"state":23,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"International Center for the Assessment of Nutritional Status and the development of Dietary Intervention Strategies (ICANS-DIS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan","RECRUITING","Milan","20133","Italy","IT",{"type":55,"coordinates":56},"Point",[57,58],9.18951,45.46427,{"lat":58,"lon":57},[61,63,65],{"name":62,"role":43,"phone":44,"phoneExt":23,"email":45},"Alessandro Leone, Prof",{"name":62,"role":64,"phone":23,"phoneExt":23,"email":23},"SUB_INVESTIGATOR",{"name":66,"role":67,"phone":23,"phoneExt":23,"email":23},"Simona Bertoli, Prof","PRINCIPAL_INVESTIGATOR",{"type":67,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Simona Bertoli","Prof.",[72],{"name":73,"class":6},"University of Florence","100648124","acute-effects-of-mct-formulations-on-beta-hydroxybutyrate-response-lipid-profile-and-glucose-levels-in-healthy-adults-100648124",false,"NCT07718048","Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults","Acute Effects of Different Medium-Chain Triglyceride (MCT) Formulations on Ketone Body Production, Plasma Lipid Profile, and Glucose Levels in Healthy Adults: a Randomized Crossover Study","Inclusion Criteria:\n\n* Healthy adult participants\n* Age between 18 and 40 years\n* Ability to understand the study procedures and provide informed consent\n\nExclusion Criteria:\n\n* Alterations in glucose or lipid metabolism\n* Diseases requiring the use of medications that affect glucose or lipid metabolism\n* Reported or diagnosed malabsorption conditions\n* Pregnancy or breastfeeding",true,"ALL","18 Years","40 Years",{"count":86,"type":87},12,"ESTIMATED","INTERVENTIONAL",[90],"NA","The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and glucose responses in healthy adults.\n\nThe main questions it aims to answer are:\n\nDo MCTs influence beta-hydroxybutyrate responses, lipid metabolism, and glucose responses differently compared to long-chain triglycerides (LCTs)?\n\nDo different types of MCTs (natural sources containing C8 to C12 versus synthetic formulations containing only C8 and C10) lead to different beta-hydroxybutyrate, lipid, and glucose responses?\n\nDoes the form in which MCTs are consumed (e.g., powders or incorporated into foods) influence beta-hydroxybutyrate production, lipid metabolism, and glucose responses?\n\nResearchers will compare five different lipid formulations to evaluate their effects on postprandial beta-hydroxybutyrate concentrations, blood lipid levels, and glucose.\n\nParticipants will:\n\nConsume five different test products on separate study visits. Provide blood samples for up to five hours after each intake for metabolic measurements.",[93,94,95],"Ketone Body","Lipid Metabolism","Glucose Response","2026-07-16",{"date":98,"type":99},"2026-07-21","ACTUAL",{"date":101,"type":99},"2026-01-13",{"date":103,"type":87},"2026-10",{"name":5,"class":6},1]