[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649016":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":91,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Hitit University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Comparator: Thoracolumbar Fascia Myofascial Release","EXPERIMENTAL","Participants in this arm will receive a single 10-minute myofascial release technique (Pilat myofascial induction crossed-hands technique, or an equivalent thoracolumbar-fascia-specific method) applied to the T10-L4 thoracolumbar fascia region while in the prone position, delivered by a certified myofascial therapist using sustained moderate pressure (1.5-2.5 kg). EEG and ECG recordings will be obtained before the intervention (supine), and again at 0-10 minutes and 30 minutes after the intervention (supine), following a \"sandwich protocol.\"",[13],"Other: Thoracolumbar Fascia Myofascial Release (Pilat MIF Crossed-Hands Technique)",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2 - Sham Comparator: Light Surface Touch (Control)","SHAM_COMPARATOR","Participants in this arm will receive light surface contact (less than 0.5 kg pressure) over the same thoracolumbar region and for the same 10-minute duration as the active treatment group, without any sliding motion or pressure variation. The condition will be presented to participants as a placebo intervention to maintain partial blinding. EEG and ECG recordings will follow the same \"sandwich protocol\" and timing as the active group.",[19],"Other: Sham (Light Surface Touch)",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Thoracolumbar Fascia Myofascial Release (Pilat MIF Crossed-Hands Technique)","A manual myofascial release technique applied for 10 minutes to the thoracolumbar fascia (T10-L4 region) in the prone position. The therapist's hands are placed in a crossed configuration over the fascia, applying sustained moderate pressure (1.5-2.5 kg) without rapid movement, aiming to release tension in the fascia's laminar and posterior layers. The technique is delivered by a certified myofascial therapist trained in the Pilat Myofascial Induction (MIF) method.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham (Light Surface Touch)","A sham condition consisting of light, static surface contact (\\\u003C0.5 kg) applied to the same thoracolumbar region as the active technique, for the same 10-minute duration and in the same prone position. No therapeutic pressure, sliding, or manipulation is applied. This condition controls for the effects of therapist contact, positioning, and expectation, isolating the specific effect of the myofascial release technique itself.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Eylem Küçük, Ph.D","CONTACT","+905067025859","eylem.kucuk@amasya.edu.tr",[37],{"facility":38,"status":25,"city":39,"state":25,"zip":40,"country":41,"countryCode":25,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Amasya University","Amasya","05100","Turkey (Türkiye)",{"type":43,"coordinates":44},"Point",[45,46],35.83306,40.65333,{"lat":46,"lon":45},[49,50,52,55,57],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"name":32,"role":51,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"name":53,"role":54,"phone":25,"phoneExt":25,"email":25},"Ertuğrul Deniz Köse, Ph.D","SUB_INVESTIGATOR",{"name":56,"role":54,"phone":25,"phoneExt":25,"email":25},"Funda Kutlu Onay, Ph.D",{"name":58,"role":54,"phone":25,"phoneExt":25,"email":25},"Alpaslan Ersöz, Ph.D",{"type":51,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":38,"oldNameTitle":25,"oldOrganization":25},"Ertugrul Deniz Kose","Assist. Prof. Dr.","100649016","acute-effects-of-thoracolumbar-fascia-myofascial-release-on-cortical-activity-100649016",false,"NCT07728617","Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity","Acute Effects of Thoracolumbar Fascia Myofascial Release Technique on Cortical Activity: A Sham-Controlled Randomized Study","MFR-EEG","Inclusion Criteria:\n\n* Age 18-25 years\n* Self-reported healthy status\n* Literate in Turkish\n\nExclusion Criteria:\n\n* Active epilepsy or seizure history\n* Diagnosed psychiatric disorder\n* Neurological disorder\n* Cardiac arrhythmia, pacemaker, or heart disease\n* Active use of psychotropic, beta-blocker, anticholinergic, or antihistaminic medication\n* Recreational substance use within the past month\n* Pregnancy\n* Active scalp lesion or dermatological pathology\n* Active chronic low back pain\n* History of lumbar disc herniation\n* History of lumbar\u002Fthoracic spine surgery\n* Active skin lesion on the back",true,"ALL","18 Years","25 Years",{"count":75,"type":76},124,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study will examine the immediate (acute) effects of a single myofascial release technique applied to the thoracolumbar fascia on brain activity in healthy young adults aged 18-25. Using a sham-controlled, randomized design, participants will be assigned to either an active treatment group, receiving a 10-minute myofascial release technique to the lower back, or a sham control group, receiving light surface touch to the same area for the same duration without any therapeutic pressure or movement.\n\nBrain activity will be recorded using a portable, 8-channel wireless EEG system before the intervention, shortly after it (0-10 minutes), and again 30 minutes later, allowing researchers to track how cortical activity changes over time. Measurements will focus on sensorimotor rhythms (mu rhythm) and posterior alpha power, along with heart rate variability, to assess whether the myofascial technique produces effects that go beyond those of simple touch. The main goal is to determine whether this hands-on technique produces a measurable, distinct pattern of brain activity compared to a sham (placebo-like) touch condition.",[82],"Healty Volunteers",[84,85,86,87,88,89,90],"Thoracolumbar fascia","Myofascial release","Electroencephalography","Sensorimotor Mu Rhythm","Cortical Activity","Sham-Controlled Trial","Heart Rate Variability","NOT_YET_RECRUITING","2026-07-27",{"date":94,"type":95},"2026-07-29","ACTUAL",{"date":97,"type":76},"2026-09-01",{"date":99,"type":76},"2028-08-31",{"name":5,"class":6},1]