[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651052":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":11,"locations":34,"responsibleParty":59,"collaborators":61,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":11,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":11,"enrollmentInfo":75,"targetDuration":11,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Johannes Kepler University of Linz","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ALS ERC 2025","ACTIVE_COMPARATOR",null,[13],"Procedure: ERC ALS 2025",{"label":15,"type":16,"description":17,"interventionNames":18},"adapted CPR algorithm","EXPERIMENTAL","* thorax compression via mechanical device (LUCAS 3)\n* head up cpr\n* use of an ITD module\n* arterial line placement\n* continuous epinephrin infusion via infusion pump\n* double sequence defibrillation",[19],"Procedure: aCPR algorithm",[21,25],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":11},"PROCEDURE","aCPR algorithm",[15],{"type":22,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"ERC ALS 2025","Placement of an IV line, placement of a supraglottic airway device or endotracheal intubation. Optional use of an intraosseus acces",[9],[30],{"name":31,"affiliation":32,"role":33},"Jens Meier, Univ. Prof.","Kepler University Hospital \u002F Johannes Kepler University","PRINCIPAL_INVESTIGATOR",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Kepler University Hospital","RECRUITING","Linz","Upper Austria","4020","Austria","AT",{"type":44,"coordinates":45},"Point",[46,47],14.28611,48.30639,{"lat":47,"lon":46},[50,55],{"name":51,"role":52,"phone":53,"phoneExt":11,"email":54},"Jens Meier, Univ. Prof. Dr. med","CONTACT","+43 5 7680 83 - 2158","jens.meier@kepleruniklinikum.at",{"name":56,"role":52,"phone":57,"phoneExt":11,"email":58},"Johannes Szasz, Dr.med","+43 5 7680 83 - 78947","johannes.szasz@jku.at",{"type":60,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[62,65],{"name":63,"class":64},"Red Cross Upper Austria","UNKNOWN",{"name":36,"class":6},"100651052","adapted-cardiopulmonary-resuscitation-study-100651052",false,"NCT07754656","Adapted Cardiopulmonary Resuscitation Study","Adapted CPR (aCPR) a Bundle of Measures for Out of Hospital Cardiac Arrest (OHCA) Patients","Inclusion Criteria:\n\n* Age\\> 18 years\n* time of resuscitation \\\u003C21 minutes when enrollement starts\n\nExclusion Criteria:\n\n* obvious pregnancy\n* contraindications for the use of Lucas 3\n* time of resuscitation \\>21 minutes and etCO2 \\\u003C15 mmHg upon arrival of the emergency physician on scene\n* Exclusion from the emergency physician from study due to futility.","ALL","18 Years",{"count":76,"type":77},216,"ESTIMATED","INTERVENTIONAL",[80],"NA","The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest. Two different algorithms (control-and interventiongroup) of advanced cardiac life support will be used to treat patients. In patients over 18 years suffering from cardiac arrest. The main question aims to answer if the frequency of ROSC differs between the groups receiving either the new Advanced Life Support (ALS) algorithm, or standard treatment.\n\nResearchers will compare the new algorithm to the standard care algorithm to see if there is a difference .\n\nParticipants will be randomized to treatment on scene. The controlgroup will receive ALS standard treatment as performed in local protocols.\n\nThe intervention group will receive a modified treatment including:\n\n* thorax compression via mechanical device (LUCAS 3)\n* head up Cardiopulmonary Resuscitation (cpr)\n* use of an impendance threshold device (ITD) module\n* arterial line placement\n* continuous epinephrin infusion via infusion pump\n* double sequence defibrillation",[83],"Cardiac Arrest (CA)",[85,86,87,88,89,90,91,92,93],"cardiac arrest","head up cpr","continuous adrenalin infusion","mechanical thorax compression","ITD","arterial line","diastolic blood pressure","ROSC","OHCA","2026-08-04",{"date":96,"type":97},"2026-08-10","ACTUAL",{"date":99,"type":97},"2026-01-28",{"date":101,"type":77},"2029-03-28",{"name":5,"class":6},1]