[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625679":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":30,"locations":38,"responsibleParty":57,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":21,"maxAge":21,"enrollmentInfo":72,"targetDuration":21,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":21,"overallStatus":40,"whyStopped":21,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Remote Exercise and Caregiver Education","EXPERIMENTAL","Single Arm with active intervention for remote exercise and caregiver education sessions",[13,14],"Behavioral: Remote Exercise Sessions","Behavioral: Caregiver Education Sessions",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","Remote Exercise Sessions","Participants will take part in thrice weekly exercise sessions using pre-recorded videos designed for older adults with Down syndrome. Participants will join video call and follow along with the video. A staff member familiar with the population will be on the call to provide modifications, encouragement and ensure participant safety.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Caregiver Education Sessions","Caregivers will join a once-weekly education session held via video call and led by a trained staff member. Education content will include how to support and manage challenging behaviors of older adults with Down syndrome who may be experiencing Alzheimer's disease-related symptoms.",[9],[27],{"name":28,"affiliation":5,"role":29},"Amy Bodde, PhD","PRINCIPAL_INVESTIGATOR",[31,35],{"name":28,"role":32,"phone":33,"phoneExt":21,"email":34},"CONTACT","913-574-2447","abodde@kumc.edu",{"name":36,"role":32,"phone":21,"phoneExt":21,"email":37},"Joseph Sherman, MS","jsherman7@kumc.edu",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Kansas City","Kansas","66160","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-94.62746,39.11417,{"lat":50,"lon":49},[53,54,56],{"name":28,"role":32,"phone":33,"phoneExt":21,"email":34},{"name":55,"role":32,"phone":21,"phoneExt":21,"email":37},"Joseph Sherman",{"name":28,"role":29,"phone":21,"phoneExt":21,"email":21},{"type":58,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR",[60],{"name":61,"class":62},"National Center for Advancing Translational Sciences (NCATS)","NIH","100625679","adapting-rdad-for-ds-100625679",false,"NCT07425769","Adapting RDAD for DS","Adapting the RDAD Intervention for Individuals With Down Syndrome Phase 3- Pilot Test","CareFit DS\u002FAD","Inclusion Criteria - Adults with Down syndrome:\n\n* Age \\>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \\~31 in adults with DS.\n* Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.\n* Living at home or in a supported living environment with a parent\u002Fcaregiver who agrees to serve as a study partner.\n* Self-reported ability to participate in physical activity.\n\nExclusion Criteria - Adults with Down syndrome:\n\n* Unable to participate in moderate-to-vigorous physical activity.\n* Self-reported, cardiovascular, metabolic or renal disease and\u002For signs or symptoms.\n\nInclusion Criteria - Caregivers\n\n* Age ≥18 yrs.\n* Reports being a primary caregiver of an adult with DS.\n* English speaking.\n* Self-reported ability to participate in physical activity.\n\nExclusion Criteria - Caregivers\n\n* Unable to participate in moderate PA, i.e., brisk walking.\n* Self-reported, cardiovascular, metabolic or renal disease and\u002For signs or symptoms.","ALL",{"count":73,"type":74},40,"ESTIMATED","INTERVENTIONAL",[77],"NA","The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.",[80,81],"Down Syndrome (DS)","Alzheimer's Disease (AD)","2026-07-31",{"date":84,"type":85},"2026-08-03","ACTUAL",{"date":87,"type":85},"2026-03-31",{"date":89,"type":74},"2026-12-31",{"name":5,"class":6},1]