[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650530":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":37,"locations":49,"responsibleParty":66,"collaborators":42,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":9,"eligibilityCriteria":73,"healthyVolunteers":70,"sex":74,"minAge":75,"maxAge":42,"enrollmentInfo":76,"targetDuration":42,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":87,"whyStopped":42,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MERA-C","EXPERIMENTAL","Phase 3\u002FAim 3 of this study involves a behavioral intervention. Manage Emotions to Reduce Aggression-Couples (MERA-C). Although the exact duration and timing of MERA-C will be established in Aim 1, the investigators anticipate that MERA-C will be the same duration as individual MERA: 4 weekly couples\u002Fdyadic therapy sessions of 45-60 minutes each.",[13],"Behavioral: Manage Emotions to Reduce Aggression- Couples",{"label":15,"type":16,"description":17,"interventionNames":18},"MERA","ACTIVE_COMPARATOR","Manage Emotions to Reduce Aggression (MERA). 4 weekly individual therapy sessions of 45-60 minutes each.",[19],"Behavioral: Manage Emotions to Reduce Aggression",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Manage Emotions to Reduce Aggression- Couples","4 weekly dyadic\u002Fcouples therapy sessions of 45-60 minutes each.",[9],[9],{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Manage Emotions to Reduce Aggression","4 weekly individual therapy sessions of 45-60 minutes each.",[15],[15],[33],{"name":34,"affiliation":35,"role":36},"Julianne Christina Flanagan, PhD","Ralph H. Johnson VA Medical Center, Charleston, SC","PRINCIPAL_INVESTIGATOR",[38,44],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Julianne C Flanagan, PhD","CONTACT","(843) 577-5011",null,"julianne.flanagan@va.gov",{"name":45,"role":40,"phone":46,"phoneExt":47,"email":48},"Stacey S Sellers, MS","(843) 789-6703","206703","Stacey.Sellers@va.gov",[50],{"facility":35,"status":42,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Charleston","South Carolina","29401-5703","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-79.93275,32.77632,{"lat":60,"lon":59},[63,64,65],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},{"name":45,"role":40,"phone":46,"phoneExt":47,"email":48},{"name":34,"role":36,"phone":42,"phoneExt":42,"email":42},{"type":67,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR","100650530","adapting-the-manage-emotions-to-reduce-aggression-therapy-to-reduce-intimate-partner-violence-and-promote-psychosocial-recovery-in-veteran-couples-mera-c-100650530",false,"NCT07749755","Adapting the Manage Emotions to Reduce Aggression Therapy to Reduce Intimate Partner Violence and Promote Psychosocial Recovery in Veteran Couples (MERA-C)","Inclusion Criteria:\n\nVeteran and Partner Inclusion criteria\n\n1. At least one partner in each couple must be a U.S. military Veteran\n2. Married, cohabiting, or in a committed relationship for at least 6 months\n3. Cognitive functioning sufficient to provide informed consent and participate accurately (≥ 23 on the Mini-Mental Status Exam \\[MMSE\\])\n4. Veteran meets criteria for subthreshold PTSD or greater (Criterion A plus scoring 2 or higher on at least one symptom from each of clusters B, C, D, and E as measured by the PCL-5)\n5. At least 1 instance of mild or moderate physical intimate partner violence (IPV) in the current relationship in the past year (as defined by the Revised Conflict Tactics Scale \\[CTS-2\\])\n6. Not currently enrolled in couple therapy\n7. Participants taking psychotropic medications will be required to be maintained on a stable dose for at least four weeks before study initiation. This is because initiation or change of psychotropic medications during the course of the trial may interfere with interpretation of results\n\nExclusion Criteria:\n\nVeteran and Partner Exclusion criteria\n\n1. Any severe physical or sexual IPV (as measured by the CTS-2) at any time in the current relationship\n2. Having a psychiatric condition requiring a higher level of care as assessed by the Quick Structured Clinical Interview for DSM-5 Disorders (QuickSCID), such as psychotic or bipolar disorders. Those participants will be referred clinically.\n3. Severe substance use disorder. Nicotine dependence is allowed. Participants requiring specialty care for substance use disorders or smoking cessation aid will be referred clinically.\n4. Current suicidal, self-harm behavior, or homicidal ideation and intent requiring a higher level of care or who are likely to require hospitalization during the study. Those participants will be referred clinically.","ALL","18 Years",{"count":77,"type":78},120,"ESTIMATED","INTERVENTIONAL",[81],"NA","This study will address a pressing unmet need for effective and accessible treatment for Veteran couples with intimate partner violence (IPV). The primary objective is to adapt a brief intervention originally developed to reduce general aggression among individual Veterans with PTSD symptoms (Manage Emotions to Reduce Aggression; MERA) to reduce IPV among Veteran couples. First, the investigators will conduct stakeholder interviews to inform the content, dose, and timing of the adapted MERA-Couples manual (MERA-C). Second, the investigators will examine the preliminary feasibility and acceptability of MERA-C through a single-arm feasibility trial among 10 Veteran couples with IPV. Finally, the investigators will conduct a pilot randomized controlled trial (N= 60 couples) to examine the preliminary within- and between-couple effects of MERA-C versus MERA on (1) participant acceptability and retention and (2) physical and psychological IPV occurrence; emotion regulation; relationship functioning; and psychosocial functioning from pre- to post-treatment and at 1-month follow-up.",[84],"Intimate Partner Violence",[86],"Couples","NOT_YET_RECRUITING","2026-07-31",{"date":90,"type":91},"2026-08-06","ACTUAL",{"date":93,"type":78},"2027-01-01",{"date":95,"type":78},"2030-09-30",{"name":5,"class":6},1]