[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525416":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":30,"responsibleParty":46,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":19,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":19,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":19,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Columbia University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Single Arm: Adherence Intervention","EXPERIMENTAL","Multicomponent Adherence Intervention",[13],"Behavioral: Multicomponent Adherence Intervention",[15],{"type":16,"name":11,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","multi-part intervention to reduce barriers to medication use",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Research Nurse Navigator","CONTACT","212-342-5162","cancerclinicaltrials@cumc.columbia.edu",{"name":27,"role":23,"phone":28,"phoneExt":19,"email":29},"Claire Sathe, MD","212-305-8923","ds1099@cumc.columbia.edu",[31],{"facility":32,"status":33,"city":34,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Columbia University Medical Center","RECRUITING","New York","10032","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-74.00597,40.71427,{"lat":42,"lon":41},[45],{"name":27,"role":23,"phone":28,"phoneExt":19,"email":29},{"type":47,"investigatorFullName":27,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Assistant Professor",[50],{"name":51,"class":52},"National Institute on Minority Health and Health Disparities (NIMHD)","NIH","100525416","adherence-intervention-in-patients-with-metastatic-breast-cancer-100525416",false,"NCT06121453","Adherence Intervention in Patients With Metastatic Breast Cancer","P50 Supplement: Improving Medications Adherence Equitably Among Patients With Metastatic Breast Cancer and Cardiovascular Disease","Inclusion Criteria:\n\n* Women or men age \\>18 years\n* Diagnosed with stage IV\u002Fmetastatic breast cancer prescribed endocrine therapy and a CDK4\u002F6i\n* Prescribed at least 1 antihypertensive or statin medication for CVD prevention or treatment\n* Self-report of at least some nonadherence ET\u002FCDK4\u002F6i or CVD medication on nonadherence screener or verbally to a treating clinician, or nonadherent to ET, CDK4\u002F6i, and\u002For CVD medication on pharmacy fill data in the EHR (proportion of days covered over prior 180 days \\\u003C80%).\n\nExclusion Criteria:\n\n* Non-English or Non-Spanish speaking\n* Not cognitively able to complete study requirements\n* Inability to provide informed consent for any other reason (e.g, severe psychiatric illness, active substance use)\n* Unavailable for 28 weeks of follow-up","ALL","18 Years","99 Years",{"count":64,"type":65},35,"ESTIMATED","INTERVENTIONAL",[68],"NA","To evaluate the preliminary efficacy of a multicomponent adherence intervention focused on enhancing digital equity and pharmaco-equity among nonadherent patients with metastatic breast cancer (MBC) and cardiovascular disease (CVD) risk factors on endocrine therapy (ET), CDK4\u002F6 inhibitor (CDK 4\u002F6i), and CVD medications. To assess the acceptability and appropriateness of this intervention in patients with MBC and CVD risk factors through validated measures of implementation outcomes. To gain a deeper understanding of the impact of social determinants of health (SDOH) on medication nonadherence through semi-structured interviews with a subset of study participants.",[71],"Breast Cancer","2026-07-27",{"date":74,"type":75},"2026-07-28","ACTUAL",{"date":77,"type":75},"2024-04-12",{"date":79,"type":65},"2026-12-10",{"name":5,"class":6},1]