[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648230":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":35,"locations":44,"responsibleParty":60,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":22,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":18,"enrollmentInfo":75,"targetDuration":18,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":93,"whyStopped":18,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Advanced HIV Re-engagement in Care (ARC)","EXPERIMENTAL","In this trial arm, participants will be provided with the ARC intervention package.",[13],"Behavioral: ARC",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care (SOC)","NO_INTERVENTION","In this arm, participants will be managed according to the standard of care.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","ARC","ARC is a multi-component package of support delivered primarily by a community health worker. It is oriented towards the medical and psychosocial and sociobehavioral challenges of advanced HIV disease and hospitalization.",[9],[26,30,33],{"name":27,"affiliation":28,"role":29},"Lottie Hachaambwa, MBChB","Ciheb Zambia","PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":32,"role":29},"Cassidy Claassen, MD","University of Maryland, Baltimore",{"name":34,"affiliation":5,"role":29},"Michael J Vinikoor, MD",[36,40],{"name":34,"role":37,"phone":38,"phoneExt":18,"email":39},"CONTACT","205-996-2416","mjv3@uab.edu",{"name":41,"role":37,"phone":42,"phoneExt":18,"email":43},"Ike Oyewole","205-934-5191","ikeoluwaoyewole@uabmc.edu",[45],{"facility":46,"status":18,"city":47,"state":18,"zip":18,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"University Teaching Hospital","Lusaka","Zambia","ZM",{"type":51,"coordinates":52},"Point",[53,54],28.28713,-15.40669,{"lat":54,"lon":53},[57],{"name":27,"role":37,"phone":58,"phoneExt":18,"email":59},"260976435603","lhachaambwa@cihebzambia.org",{"type":29,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Michael Vinikoor","Professor of Medicine",[64,66],{"name":28,"class":65},"UNKNOWN",{"name":32,"class":6},"100648230","advanced-hiv-re-engagement-in-care-100648230",false,"NCT07720128","Advanced HIV Re-engagement in Care","Inclusion Criteria:\n\n* Living with HIV\n* Advanced HIV defined as CD4 \\\u003C350 cells\u002Fmm3 or WHO stage 3 or 4 event\n* Currently admitted to study hospital's internal medicine department\n\nExclusion Criteria:\n\n* Planning to reside outside Lusaka after discharge\n* Too sick to provide informed consent\n* Known to have advanced cancer (defined as requiring chemo\u002Fradiation therapy or referred to hospice) other than Kaposi Sarcoma\n* Known to have end stage kidney disease\n* Known to have end stage liver disease\n* No access to a telephone\n* Currently incarcerated","ALL","18 Years",{"count":76,"type":77},724,"ESTIMATED","INTERVENTIONAL",[80],"NA","Adults who are hospitalized in Lusaka, Zambia, and found to have advanced HIV disease will be enrolled and randomly assigned to receive the ARC intervention or standard of care. All participants will then be followed through the end of the hospitalization and for up to 1 year after discharge from hospital.",[83],"Advanced HIV Disease",[85,86,87,88,89,90,91,92],"HIV\u002FAIDS","Transitions of care","Hospitalization","Community Health Worker","Sub-Saharan Africa","Advanced HIV disease","Tuberculosis","Cryptococcus","NOT_YET_RECRUITING","2026-07-22",{"date":96,"type":97},"2026-07-23","ACTUAL",{"date":99,"type":77},"2027-05-01",{"date":101,"type":77},"2031-08-01",{"name":5,"class":6},1]