[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656108":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":23,"studyPopulation":13,"armGroups":24,"interventions":35,"overallOfficials":13,"centralContacts":41,"locations":50,"responsibleParty":74,"collaborators":13,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":13,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":13,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":53,"whyStopped":13,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Combined Military Hospital Bahawalpur","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Beck Depression Inventory (BDI) score","The primary outcome will be the mean change in Beck Depression Inventory (BDI) score from baseline to the end of 06 weeks intervention period. It is a 21- item self-report scale with total scores ranging from 0 to 63. Lower scores indicate fewer depressive symptoms and therefore a better outcome. The mean change in BDI score will be compared between the aerobic exercise (plus conventional treatment ) group and the non exercise group. (conventional treatment only).","Baseline to 06 weeks",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":18,"observationalModel":13,"timePerspective":13,"maskingInfo":19},"RANDOMIZED","PARALLEL","RCT","TREATMENT",{"masking":20,"maskingDescription":13,"whoMasked":21},"SINGLE",[22],"OUTCOMES_ASSESSOR","This study will compare two groups A and B for 06 weeks to study the reduction in severity of depression.\n\n* Comparison group (Group-A): In this group participants will receive standard antidepressant treatment such as Sertraline (SSRIs) and psychotherapy (CBT) only. After 06 weeks, patients will again be assessed for their level of depression using the BDI scale.\n* Experimental group (Group-B): In this group participants will undergo structured exercise program in addition to conventional pharmacotherapy and psychotherapy. They will be introduced to aerobic exercises which includes cycling and brisk walking and will undergo three supervised sessions for 35 minutes each, per week for total 06 weeks under supervision of trainee psychiatry.",[25,29],{"label":26,"type":27,"description":28,"interventionNames":13},"Comparison","NO_INTERVENTION","Participants will receive conventional treatment only for 06 weeks",{"label":30,"type":31,"description":32,"interventionNames":33},"Aerobic Exercise","EXPERIMENTAL","Participants will receive structured aerobic exercise cycling or brisk walking in addition to conventional treatment for 06 weeks",[34],"Behavioral: Structured Aerobic exercise",[36],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":13},"BEHAVIORAL","Structured Aerobic exercise","Participants will receive structured, supervised aerobic exercise ( cycling, brisk walking), in addition to conventional treatment consisting of 03 sessions per week, 35 minutes each for 06 weeks.",[30],[42,47],{"name":43,"role":44,"phone":45,"phoneExt":13,"email":46},"Manahil Gill, MBBS","CONTACT","+92 304 6527981","manahilgill143@gmail.com",{"name":48,"role":44,"phone":49,"phoneExt":13,"email":13},"Muhammad Ahsan Mustafa, MBBS","+ 92 333 3396180",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"CMH Bahawalpur","RECRUITING","Chak Four Hundred Fifty-four","Punjab Province","63100","Pakistan","PK",{"type":60,"coordinates":61},"Point",[62,63],72.44769,31.26081,{"lat":63,"lon":62},[66,67,70,72],{"name":43,"role":44,"phone":45,"phoneExt":13,"email":46},{"name":68,"role":69,"phone":13,"phoneExt":13,"email":13},"Manahil Gill, MBBS, Registrar Psychiatry","PRINCIPAL_INVESTIGATOR",{"name":71,"role":69,"phone":13,"phoneExt":13,"email":13},"Beenish Hassan Khan, MBBS, FCPS Psychiatry",{"name":73,"role":69,"phone":13,"phoneExt":13,"email":13},"Mansoor Mustafa, MBBS, FCPS Psychiatry",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"SPONSOR_INVESTIGATOR","Manahil Gill","Registrar Psychiatry, Combined Military Hospital Bahawalpur","100656108","aerobic-exercise-as-an-adjunct-therapy-for-depression-100656108",false,"NCT07819448","Aerobic Exercise as an Adjunct Therapy for Depression","Role of Aerobic Exercise as an Adjunct Therapy in the Treatment of Depression in South Punjab, Pakistan","Inclusion Criteria:\n\ni. All new patients diagnosed with moderate and severe depression using BDI scale according to ICD-11 criteria between the ages of 18-55 years.\n\nii. Both genders will be included.\n\nExclusion Criteria:\n\ni. Patients with severe physical disabilities such as Spinal cord injuries, severe osteoporosis or medical conditions that prevent exercise such as ischemic changes in ECG pre-exercise.\n\nii. Pregnant females. iii. Individuals already engaging in physical activities like athletes.","ALL","18 Years","55 Years",{"count":89,"type":90},66,"ESTIMATED","INTERVENTIONAL",[93],"NA","The goal of this study is to compare the reduction in the severity of depression after a duration of 06 weeks between patients receiving conventional therapy (antidepressant; Sertraline) only and those receiving both conventional therapy and a structured aerobic exercise (cycling, brisk walking).",[96],"Depressive Disorder",[98,99,100,101,102],"Depression","Aerobic exercise","Antidepressant therapy","Psychotherapy","Beck Depression Inventory (BDI)","2026-09-14",{"date":105,"type":106},"2026-09-17","ACTUAL",{"date":108,"type":106},"2026-06-01",{"date":110,"type":90},"2027-02-01",{"name":76,"class":6},1]