[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650752":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":11,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":11,"overallStatus":72,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Alexandria University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Test Group","EXPERIMENTAL",null,[13],"Other: macroabrasion followed by oxidative pretreatment",{"label":15,"type":16,"description":11,"interventionNames":17},"Control Group","ACTIVE_COMPARATOR",[18],"Other: macroabrasion alone",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"macroabrasion followed by oxidative pretreatment","Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer, then 5.25% sodium hypochlorite will be applied to the labial lesion surface and agitated with a microbrush for one minute, then rinsed for 20 seconds.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"macroabrasion alone","Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer,",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},"Maryam AbdulAziz","CONTACT","01033254672","coolmaryomi96@gmail.com",[35],{"facility":36,"status":11,"city":37,"state":11,"zip":11,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Outpatient Clinic of Pediatric dentistry, Faculty of dentistry, Alexandria University, Egypt","Alexandria","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],29.91582,31.20176,{"lat":44,"lon":43},[47,48],{"name":5,"role":31,"phone":11,"phoneExt":11,"email":11},{"name":49,"role":50,"phone":11,"phoneExt":11,"email":11},"Mariam AbdulAziz, BDS","PRINCIPAL_INVESTIGATOR",{"type":52,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100650752","aesthetic-masking-and-resin-infiltration-time-in-mih-affected-incisors-100650752",false,"NCT07753070","Aesthetic Masking and Resin Infiltration Time in MIH-affected Incisors","Effectiveness of Transillumination-Guided Surface Pretreatment on Aesthetic Masking and Resin Infiltration Time in MIH-affected Incisors (A Randomised Clinical Trial)","Inclusion Criteria:\n\n* Healthy children with MIH-related mild white creamy opacities on permanent incisors, code 1 according to the European Academy of Paediatric Dentistry (EAPD) criteria.\n* Clinically detectable isolated lesions (whether homogeneous or heterogeneous on the incisal and middle thirds of the buccal surface of the selected teeth.\n* Patients with score 3 (positive) or score 4 (definitely positive) according to Frankl behavioral rating scale\n* Parents or legal guardians accepting to sign a written consent and join the study\n\nExclusion Criteria:\n\n* MIH-affected permanent incisors with post-eruptive enamel breakdown, cavitated lesions, restorations, or previously treated with surface layer removal or remineralising agents in the previous six months.\n* Children with an allergy history","ALL","8 Years","13 Years",{"count":64,"type":65},100,"ESTIMATED","INTERVENTIONAL",[68],"NA","Background: Resin infiltration often shows unpredictable outcomes in teeth affected by molar incisor hypomineralisation (MIH) due to variable enamel porosities, hypermineralised surface layers, and elevated protein content. Different pretreatment modalities alongside modified resin infiltration protocols have been suggested to enhance aesthetic masking and the required resin infiltration time.\n\nAim: To compare the effectiveness of transillumination-guided 5.25% NaOCl pretreatment following macroabrasion, with macroabrasion alone, each with 10-second hydrochloric acid (HCl) etching intervals, on aesthetic masking and resin infiltration time required in MIH-affected incisors.",[71],"Molar Incisor Hypomineralization","NOT_YET_RECRUITING","2026-08-04",{"date":75,"type":76},"2026-08-07","ACTUAL",{"date":78,"type":65},"2026-08-10",{"date":80,"type":65},"2027-03-30",{"name":5,"class":6},1]