[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623143":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":77,"collaborators":18,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":18,"maxAge":18,"enrollmentInfo":88,"targetDuration":18,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":66,"whyStopped":18,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients starting long-term parenteral nutrition","Observational follow-up of patients starting long-term parenteral nutrition",[12],"Other: Non-invasive skin AGE measurements",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Non-invasive skin AGE measurements","Non-invasive skin AGE measurements at baseline, 6 and 12 months; collection and analysis of parenteral nutrition bag samples; routine metabolic assessments; dietary records, glucose holter, plasma glycated hemoglobin and fructosamine assays.",[9],null,[20],{"name":21,"affiliation":5,"role":22},"Florian POULLENOT, MD","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},"CONTACT","+335 57 65 64 40","florian.poullenot@chu-bordeaux.fr",{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},"Raphaël ENAUD, MD","+335 56 79 98 24","raphael.enaud@chu-bordeaux.fr",[33,49,64],{"facility":34,"status":35,"city":36,"state":18,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"CHU de Bordeaux-Hôpital des enfants GH Pellegrin","NOT_YET_RECRUITING","Bordeaux","33076","France","FR",{"type":41,"coordinates":42},"Point",[43,44],-0.58046,44.84124,{"lat":44,"lon":43},[47,48],{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},{"name":29,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":50,"status":35,"city":51,"state":18,"zip":52,"country":38,"countryCode":39,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"AP-HP - Hopital Robert Debré","Paris","75935",{"type":41,"coordinates":54},[55,56],2.3488,48.85341,{"lat":56,"lon":55},[59,63],{"name":60,"role":25,"phone":61,"phoneExt":18,"email":62},"Emmanuelle ECOCHARD-DUGELAY, MD","+331.87.89.16.46","emmanuelle.dugelay@aphp.fr",{"name":60,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":65,"status":66,"city":67,"state":18,"zip":68,"country":38,"countryCode":39,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"CHU de Bordeaux - Hôpital Haut Lévêque","RECRUITING","Pessac","33600",{"type":41,"coordinates":70},[71,72],-0.6324,44.80565,{"lat":72,"lon":71},[75,76],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},{"name":21,"role":22,"phone":18,"phoneExt":18,"email":18},{"type":78,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100623143","age-accumulation-in-patients-on-long-term-parenteral-nutrition-100623143",false,"NCT07392801","AGE Accumulation in Patients on Long-term Parenteral Nutrition","Study of Advanced Glycation End-products Accumulation in Patients Under Long-Term Parenteral Nutrition (NUPARAGE2)","NUPARAGE2","Inclusion Criteria:\n\n* Patients (adults and children, all ages) initiating long-term parenteral nutrition\n* Followed at CHU de Bordeaux or Robert Debré Hospital (APHP)\n* Covered by French Social Security system\n* Written informed consent obtained from patient (if adult) or legal guardian (if minor)\n\nExclusion Criteria:\n\n* Fitzpatrick skin type ≥ V (darker skin tones)\n* Forearm tattoos at the site of measurement\n* For patients included under 1 year of age: patients born prematurely (before 37 weeks of amenorrhea)\n* Pregnant or breastfeeding women.","ALL",{"count":89,"type":90},50,"ESTIMATED","INTERVENTIONAL",[93],"NA","This prospective and observational study aims to evaluate the accumulation of advanced glycation end-products (AGEs) in adult and pediatric patients starting long-term parenteral nutrition, by non-invasive skin AGE measurements over a 12-month follow-up.",[96,97,98],"Chronic Intestinal Insufficiency","Advanced Glycation and Products","Parenteral Nutrition",[100,101,102,103,104,105,106],"parenteral nutrition","Advanced Glycation End Products","Oxidative Stress","Metabolic Diseases","Cardiovascular Diseases","Short Bowel Syndrome","chronic intestinal insufficiency","2026-07-23",{"date":109,"type":110},"2026-07-24","ACTUAL",{"date":112,"type":110},"2026-07-22",{"date":114,"type":90},"2028-07",{"name":5,"class":6},3]