[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643377":3},{"organization":4,"outcomesModule":7,"designInfo":75,"detailedDescription":83,"studyPopulation":74,"armGroups":84,"interventions":100,"overallOfficials":74,"centralContacts":110,"locations":116,"responsibleParty":133,"collaborators":137,"id":141,"slug":142,"hasResults":143,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":149,"sex":150,"minAge":151,"maxAge":152,"enrollmentInfo":153,"targetDuration":74,"studyType":156,"phases":157,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":119,"whyStopped":74,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":173},{"fullName":5,"class":6},"Seoul National University Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":21,"otherOutcomes":74},[9,13,17],{"measure":10,"description":11,"timeFrame":12},"Change in Dietary Behavior Score","Dietary behavior will be assessed using a 12-item dietary behavior questionnaire derived from a 19-item dietary assessment questionnaire developed and routinely used at Seoul National University Hospital Gangnam Center. Each item is scored on a 3-point scale (1, 3, or 5 points). Total scores range from 12 to 60, with higher scores indicating healthier dietary behaviors. The change in total dietary behavior score from baseline to 12 weeks will be evaluated. unit:score","Baseline and 12 weeks",{"measure":14,"description":15,"timeFrame":16},"Outcome Measure: Change in Client Satisfaction Questionnaire Score (CSQ-8)","Participant satisfaction with the system will be assessed using the Client Satisfaction Questionnaire-8 (CSQ-8). Total scores range from 8 to 32, with higher scores indicating greater satisfaction with the system.unit:score","from baseline to 12 weeks.",{"measure":18,"description":19,"timeFrame":20},"Change in System Usability Scale Score (SUS)","System usability will be assessed using the System Usability Scale (SUS). Total scores range from 0 to 100, with higher scores indicating better usability. unit:score","from baseline to 12 weeks",[22,25,28,31,35,38,41,44,47,50,53,56,59,62,65,68,71],{"measure":23,"description":24,"timeFrame":12},"Change in Body Mass Index","Change in body mass index from baseline to 12 weeks. Unit: kg\u002Fm²",{"measure":26,"description":27,"timeFrame":20},"Change in Waist Circumference","Change in waist circumference from baseline to 12 weeks. Unit : cm",{"measure":29,"description":30,"timeFrame":16},"Change in Systolic Blood Pressure","Change in systolic blood pressure from baseline to 12 weeks.Unit:mmHg",{"measure":32,"description":33,"timeFrame":34},"Change in Diastolic Blood Pressure","Change in diastolic blood pressure from baseline to 12 weeks. Unit:mmHg","from baseline to 12 week",{"measure":36,"description":37,"timeFrame":16},"Change in Fasting Glucose","Change in fasting glucose from baseline to 12 weeks. Unit:mg\u002FdL",{"measure":39,"description":40,"timeFrame":34},"Change in HbA1c","Change in HbA1c from baseline to 12 weeks.Unit:%",{"measure":42,"description":43,"timeFrame":20},"Change in total cholesterol","Changes in total cholesterol from baseline to 12 weeks. unit: mg\u002FdL",{"measure":45,"description":46,"timeFrame":20},"Change in AST","Changes in AST from baseline to 12 weeks.unit: U\u002FL",{"measure":48,"description":49,"timeFrame":20},"Change in Body fat mass","Changes in body fat mass from baseline to 12 weeks. unit : kg",{"measure":51,"description":52,"timeFrame":20},"Change in skeletal muscle mass","Changes in skeletal muscle mass from baseline to 12 weeks. unit:kg",{"measure":54,"description":55,"timeFrame":16},"Change in percent body fat","Changes in percent body fat from baseline to 12 weeks. unit:%",{"measure":57,"description":58,"timeFrame":20},"Change in body weight (kg)","Change in body weight from baseline to 12 weeks unit: kg",{"measure":60,"description":61,"timeFrame":20},"Changes in LDL cholesterol","Changes in LDL cholesterol from baseline to 12 weeks. unit: mg\u002FdL",{"measure":63,"description":64,"timeFrame":20},"Changes in HDL cholesterol","Changes in HDL cholesterol from baseline to 12 weeks. unit: mg\u002FdL",{"measure":66,"description":67,"timeFrame":16},"Changes in triglycerides","Changes in triglycerides from baseline to 12 weeks.",{"measure":69,"description":70,"timeFrame":20},"Changes in ALT","Changes in ALT from baseline to 12 weeks.unit: U\u002FL",{"measure":72,"description":73,"timeFrame":20},"Changes in γ-GTP","Changes in γ-GTP from baseline to 12 weeks.unit: U\u002FL",null,{"allocation":76,"interventionModel":77,"interventionModelDescription":78,"primaryPurpose":79,"observationalModel":74,"timePerspective":74,"maskingInfo":80},"RANDOMIZED","PARALLEL","Participants will be randomly assigned to either an AI-based personalized dietary management intervention group or a control group receiving standard nutritional information. The study will be conducted in a parallel-group design to evaluate the effectiveness of the intervention on metabolic health and dietary behaviors.","PREVENTION",{"masking":81,"maskingDescription":82,"whoMasked":74},"NONE","This is an open-label study. Participants and investigators will be aware of group assignments.","This study is a randomized controlled trial designed to evaluate whether an Agentic AI-based personalized dietary management algorithm improves dietary behavior and metabolic health indicators among adults undergoing health screening. Eligible participants will be randomly assigned to one of three groups: standard dietary education and passive dietary recording, AI-generated personalized dietary goals maintained throughout the study period, or adaptive AI-based dietary tracking with dynamic goal adjustment and personalized feedback. Outcomes will be assessed at baseline and after 12 weeks, including dietary evaluation index scores and metabolic health-related clinical indicators.",[85,89,95],{"label":86,"type":87,"description":88,"interventionNames":74},"Control group","NO_INTERVENTION","Participants receive standard dietary education and perform passive dietary recording during the 12-week study period.",{"label":90,"type":91,"description":92,"interventionNames":93},"Static goal AI intervention group","EXPERIMENTAL","Participants receive AI-generated personalized dietary goals that are maintained during the 12-week intervention period.",[94],"Behavioral: Static AI-based personalized dietary goal setting",{"label":96,"type":91,"description":97,"interventionNames":98},"Adaptive goal AI intervention group","Participants receive adaptive AI-based dietary tracking, dynamic goal adjustment, and personalized feedback during the 12-week intervention period.",[99],"Behavioral: Adaptive AI-based personalized dietary management",[101,106],{"type":102,"name":103,"description":104,"armGroupLabels":105,"otherNames":74},"BEHAVIORAL","Static AI-based personalized dietary goal setting","The AI algorithm generates individualized dietary goals based on baseline information. The generated goals are maintained without dynamic adjustment during the intervention period.",[90],{"type":102,"name":107,"description":108,"armGroupLabels":109,"otherNames":74},"Adaptive AI-based personalized dietary management","The AI algorithm monitors dietary records and relevant participant information, adjusts dietary goals dynamically, and provides personalized feedback to support dietary behavior change.",[96],[111],{"name":112,"role":113,"phone":114,"phoneExt":74,"email":115},"Suyeon Choi, MD, PhD","CONTACT","02-2112-5639","65390@snuh.org",[117],{"facility":118,"status":119,"city":120,"state":120,"zip":121,"country":122,"countryCode":74,"cosmosGeoPoint":123,"geoPoint":128,"contacts":129},"Seoul National University Hospital Healthcare System Gangnam Center","RECRUITING","Seoul","06236","South Korea",{"type":124,"coordinates":125},"Point",[126,127],126.9784,37.566,{"lat":127,"lon":126},[130],{"name":131,"role":113,"phone":132,"phoneExt":74,"email":115},"Su-Yeon Choi, PhD","+82-10-2028-5782",{"type":134,"investigatorFullName":135,"investigatorTitle":136,"investigatorAffiliation":5,"oldNameTitle":74,"oldOrganization":74},"PRINCIPAL_INVESTIGATOR","Su-Yeon Choi","Professor",[138],{"name":139,"class":140},"Ministry of Agriculture, Food and Rural Affairs","UNKNOWN","100643377","agentic-ai-personalized-dietary-management-study-100643377",false,"NCT07638241","Agentic AI Personalized Dietary Management Study","Effectiveness of an Agentic AI-Based Personalized Dietary Management Algorithm in Health Screening Participants: A Randomized Controlled Trial","AIDiet","Inclusion Criteria:\n\n* Adults aged 20 years or older\n* Individuals from the general population who underwent a health examination at the Seoul National University Hospital Healthcare System Gangnam Center\n* Individuals who are capable of independently using a smartphone and operating study-related applications or text messaging functions\n* Individuals without conditions that significantly interfere with standard dietary management, as specified in the exclusion criteria \\[Section 9.2 Exclusion Criteria\\]\n\nExclusion Criteria:\n\n* Individuals unable to use a smartphone or study-related digital program\u002Fapplication, including those without a smartphone or unable to operate text messaging or application-based functions.\n* End-stage renal disease or patients currently receiving dialysis\n* Active cancer or currently undergoing chemotherapy or radiotherapy\n* Severe heart failure, liver cirrhosis, or hepatic insufficiency accompanied by varices, bleeding, ascites, hepatic encephalopathy, or jaundice\n* Malabsorption disorders such as Crohn's disease or short bowel syndrome\n* Poorly controlled hyperthyroidism or hypothyroidism\n* Diagnosed eating disorders or severe psychiatric disorders\n* Pregnant or breastfeeding women, or women who may become pregnant during study participation.\n* Individuals with recent major weight-related interventions or extreme body weight changes within the past 3 months, including:Bariatric surgery such as gastrectomy or gastric bypass surgery Newly initiated anti-obesity pharmacotherapy (e.g., semaglutide\u002FWegovy, tirzepatide\u002FMounjaro)\n* Individuals considered by the investigator to have poor compliance potential or otherwise deemed unsuitable for participation in the clinical study.",true,"ALL","20 Years","90 Years",{"count":154,"type":155},200,"ESTIMATED","INTERVENTIONAL",[158],"NA","This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening. Participants will be assigned to a control group, a static goal AI intervention group, or an adaptive goal AI intervention group and followed for 12 weeks.",[161],"Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk",[163],"Agentic AI; Personalized Nutrition; Digital Health; AI Coaching; Precision Nutrition; Dietary Management; Health Screening","2026-09-11",{"date":166,"type":167},"2026-09-15","ACTUAL",{"date":169,"type":167},"2026-06-11",{"date":171,"type":155},"2028-12-31",{"name":5,"class":6},1]