[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654063":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":15,"studyPopulation":16,"armGroups":11,"interventions":17,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":44,"collaborators":11,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":11,"maxAge":11,"enrollmentInfo":55,"targetDuration":11,"studyType":58,"phases":11,"briefSummary":59,"conditions":60,"keywords":11,"overallStatus":63,"whyStopped":11,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Al-Azhar University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"The accuracy of artificial intelligence in histopathological diagnosis of Mycosis fungoides will be evaluated by sensitivity and specificity",null,"1 year",{"allocation":11,"interventionModel":11,"interventionModelDescription":11,"primaryPurpose":11,"observationalModel":6,"timePerspective":14,"maskingInfo":11},"RETROSPECTIVE","Mycosis fungoides (MF) is the most common form of primary cutaneous T-cell lymphoma. Its early histological features may overlap with benign inflammatory dermatoses, making diagnosis challenging.\n\nThis observational study aims to evaluate the diagnostic performance of HistoGPT in the histopathological diagnosis of MF compared with certified dermatopathologists.\n\nH\\&E-stained skin biopsy slides will be digitized using a Leica Aperio GT450 whole-slide scanner at 40× magnification.\n\nThe resulting whole-slide images will be analyzed using HistoGPT, an AI-based histopathology platform.\n\nThe diagnostic performance of HistoGPT and certified dermatopathologists will be assessed and compared using appropriate diagnostic metrics, including accuracy, sensitivity, specificity, F1 score, and area under the ROC curve.\n\nThe findings of this study will help determine whether Artificial intelligence can serve as a diagnostic support tool for the histopathological diagnosis of mycosis fungoides.","H\\&E stained glass slides of MF cases will be collected from the pathology archive of Al hussein dermatopathology unit",[18],{"type":6,"name":19,"description":20,"armGroupLabels":11,"otherNames":11},"this study does not include any intervention","Does not include intervention",[22],{"name":23,"affiliation":24,"role":25},"Shimaa Ali Ahmed","Al Azhar university for boys","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":11,"email":31},"Shimaa Ali Ahmed, Resident of dermatology","CONTACT","+201024466776","shimaaali038@gmail.com",[33],{"facility":34,"status":11,"city":35,"state":11,"zip":11,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":11},"Faculty of Medicine , Al Azhar university , Nasr city , Cairo , Egypt","Cairo","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],31.24967,30.06263,{"lat":42,"lon":41},{"type":25,"investigatorFullName":23,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Resident Dermatologist","100654063","ai-in-mf-diagnosis-100654063",false,"NCT07795242","AI in MF Diagnosis","Evaluation of Artificial Intelligence Algorithms Performance in the Histopathological Diagnosis of Mycosis Fungoides","AI\\MF","Inclusion Criteria:\n\n* Slides will be included in the study if they meet the following criteria:\n\n  * Histopathological slides diagnosed as MF.\n  * Slides with adequate staining and preservation allowing clear visualization of histopathological features.\n\nExclusion Criteria:\n\n* Slides will be excluded if they meet any of the following criteria:\n\n  * Slides with poor staining quality or significant artifacts interfering with histopathological interpretation.\n  * Slides that were damaged, faded, or inadequately preserved.\n  * Slides with uncertain or inconclusive original diagnoses.\n  * Slides that could not be successfully digitized due to technical limitations ex very short or too long slides.","ALL",{"count":56,"type":57},50,"ESTIMATED","OBSERVATIONAL","The aim of this observational study is to evaluate the diagnostic performance of an AI algorithm in the histopathological diagnosis of MF compared to certified dermatopathologists.",[61,62],"Mycosis Fungoides of Skin (Diagnosis)","Artificial Intelligence (AI) in Diagnosis","NOT_YET_RECRUITING","2026-08-28",{"date":66,"type":67},"2026-08-31","ACTUAL",{"date":69,"type":57},"2026-10-01",{"date":71,"type":57},"2027-12-01",{"name":5,"class":6},1]