[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650319":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":11,"responsibleParty":26,"collaborators":11,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":34,"acronym":9,"eligibilityCriteria":35,"healthyVolunteers":32,"sex":36,"minAge":37,"maxAge":38,"enrollmentInfo":39,"targetDuration":11,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":48,"overallStatus":51,"whyStopped":11,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":11},{"fullName":5,"class":6},"Brigham and Women's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Neurofeedback","EXPERIMENTAL",null,[13],"Device: EEG Neurofeedback",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DEVICE","EEG Neurofeedback","Participants will receive a brief course of EEG-based neurofeedback consisting of three sessions over approximately one week. During each session, scalp electrodes are placed to record brain activity using electroencephalography (EEG). Real-time feedback is provided to guide participants in modulating their brain activity.\n\nThe neurofeedback protocol targets downregulation of alpha-band activity (8-12 Hz). Training is delivered using a standardized protocol with real-time visual and\u002For auditory feedback. Each session lasts approximately 20 minutes, with additional time for setup and brief assessments.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Naomi Rosenblum","CONTACT","8572054415","nrosenblum@bwh.harvard.edu",{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Olga Terechin, MD","MD","100650319","alpha-down-eeg-neurofeedback-for-alcohol-use-disorder-feasibility-trial-100650319",false,"NCT07746154","Alpha Down EEG Neurofeedback for Alcohol Use Disorder: Feasibility Trial","Inclusion Criteria:\n\nAdults ages 18-65 Meets DSM-5 criteria for current Alcohol Use Disorder Willing and able to provide informed consent Participants must report alcohol consumption within the past 30 days. Not requiring inpatient withdrawal management at the time of enrollment\n\nExclusion Criteria:\n\nHistory of epilepsy or seizure disorder (excluding uncomplicated alcohol withdrawal seizures) Current psychosis, mania, or acute suicidality, or any psychiatric condition that would impair the ability to provide informed consent or safely participate Acute alcohol intoxication at the time of study visits (as determined by breathalyzer) Pregnancy or breastfeeding Implanted electronic medical devices or metal in the head (excluding dental work), if incompatible with EEG procedures Severe cognitive impairment interfering with informed consent or participation Any medical or psychiatric condition that, in the opinion of the investigators, would make participation unsafe or interfere with study procedures","ALL","18 Years","65 Years",{"count":40,"type":41},10,"ESTIMATED","INTERVENTIONAL",[44],"NA","This pilot study is testing a short brain training program called neurofeedback in adults with alcohol use disorder. Participants will complete three sessions over about one week. The goal is to learn if this approach is easy to complete, well tolerated, and acceptable to participants. We will also explore whether it is associated with changes in alcohol cravings and drinking.",[47],"Alcohol Use Disorder (AUD)",[49,50],"Alcohol Use Disorder","EEG neurofeedback","NOT_YET_RECRUITING","2026-07-30",{"date":54,"type":55},"2026-08-04","ACTUAL",{"date":57,"type":41},"2026-08-01",{"date":59,"type":41},"2028-02-01",{"name":5,"class":6}]