[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603199":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":32,"overallOfficials":38,"centralContacts":42,"locations":52,"responsibleParty":70,"collaborators":13,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":13,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":13,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":13,"overallStatus":93,"whyStopped":13,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Nationwide Children's Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Amplitude","Average amplitude of the evoked response of the muscles.","First 30 minutes of surgery",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"NON_RANDOMIZED","PARALLEL","DIAGNOSTIC",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21,27],{"label":22,"type":23,"description":24,"interventionNames":25},"Infants","EXPERIMENTAL","Infants 28 days to 3 months old undergoing surgery.",[26],"Device: TetraGraph",{"label":28,"type":29,"description":30,"interventionNames":31},"Adolescents","ACTIVE_COMPARATOR","Adolescents\u002Fyoung adults 12 years of age or above undergoing surgery.",[26],[33],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":13},"DEVICE","TetraGraph","TetraGraph is a unique, EMG-based portable device for quantitative (objective) monitoring of neuromuscular function. It is a precise and easy to use tool for monitoring depth of block, ensuring adequate recovery of muscle function, and aiding the clinician to reduce the incidence of residual block.",[28,22],[39],{"name":40,"affiliation":5,"role":41},"Joseph D Tobias, MD","PRINCIPAL_INVESTIGATOR",[43,48],{"name":44,"role":45,"phone":46,"phoneExt":13,"email":47},"Julie Rice-Weimer, RN","CONTACT","614-355-3142","julie.rice-weimer@nationwidechildrens.org",{"name":49,"role":45,"phone":50,"phoneExt":13,"email":51},"Catherine Roth, MPH","614-722-2997","catherine.roth@nationwidechildrens.org",[53],{"facility":5,"status":13,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Columbus","Ohio","43205","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-82.99879,39.96118,{"lat":63,"lon":62},[66,68],{"name":44,"role":45,"phone":46,"phoneExt":13,"email":67},"Julie.Rice-Weimer@nationwidechildrens.org",{"name":69,"role":41,"phone":13,"phoneExt":13,"email":13},"Joseph Tobias, MD",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"SPONSOR_INVESTIGATOR","Joseph D. Tobias","Chief - Dept. of Anesthesiology & Pain Medicine","100603199","an-evaluation-of-the-neuromuscular-junction-in-neonates-using-the-tetragraph-100603199",false,"NCT07133412","An Evaluation of the Neuromuscular Junction in Neonates Using the TetraGraph","An Evaluation of the Neuromuscular Junction in Infants Using Train-of-four Monitoring With the TetraGraph™ Neuromuscular Transmission Monitor","Inclusion Criteria:\n\n* ASA 1-3 patients\n* Aged 28 days - 3 months or ≥ 12 years\n* Undergoing a surgical procedure with a volatile-agent based anesthetic that does not require administration of a neuromuscular blocking agent\n\nExclusion Criteria:\n\n* Patients with history of a peripheral neurologic or neuropathic disorder\n* Patients in whom the upper extremity cannot be used for TOF monitoring\n* Patients undergoing a surgical procedure in which neuromuscular blockade is required\n* Edematous patients\n* Patients receiving total intravenous anesthesia (TIVA)","ALL","28 Days","25 Years",{"count":85,"type":86},100,"ESTIMATED","INTERVENTIONAL",[89],"NA","The goal of this study is to use electromyography-based train-of-four monitoring (TetraGraph™ Neuromuscular Transmission Monitor) as a means of evaluating differences in neuromuscular transmission between infants ≤ 3 months of age and adolescent and older patients (≥ 12 years of age).",[92],"Surgery","NOT_YET_RECRUITING","2026-09-04",{"date":96,"type":97},"2026-09-09","ACTUAL",{"date":99,"type":86},"2026-09",{"date":101,"type":86},"2027-12",{"name":72,"class":6},1]