[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598277":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":29,"studyPopulation":33,"armGroups":34,"interventions":40,"overallOfficials":45,"centralContacts":49,"locations":55,"responsibleParty":736,"collaborators":29,"id":738,"slug":739,"hasResults":740,"nctId":741,"briefTitle":742,"officialTitle":742,"acronym":29,"eligibilityCriteria":743,"healthyVolunteers":740,"sex":744,"minAge":745,"maxAge":29,"enrollmentInfo":746,"targetDuration":29,"studyType":749,"phases":29,"briefSummary":750,"conditions":751,"keywords":29,"overallStatus":58,"whyStopped":29,"lastUpdateSubmitDate":753,"lastUpdatePostDateStruct":754,"startDateStruct":757,"completionDateStruct":759,"leadSponsor":761,"locationsCount":762},{"fullName":5,"class":6},"University of Minnesota","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":29,"otherOutcomes":29},[9,13,16,19,23,26],{"measure":10,"description":11,"timeFrame":12},"Day 28 Mortality","All-cause mortality","Day 28",{"measure":14,"description":15,"timeFrame":12},"Days to recovery scale (DRS)","The Days to Recovery Scale (DRS) is an ordinal ranked outcome that includes the concepts of mortality and time to recovery, with recovery defined as being discharged from the hospital and reaching home for the duration of the follow- up. At the end of the follow-up period, each patient is classified into one of the DRS categories based on vital status, hospitalization status, and duration it took to reach recovery.",{"measure":17,"description":18,"timeFrame":12},"Time to Sustained Recovery","Time to sustained recovery is defined as being discharged from the index hospitalization, followed by being alive and home for 14 days.",{"measure":20,"description":21,"timeFrame":22},"Ordinal outcome for clinical improvement - Day 7","For respiratory infections, the WHO Ordinal Scale for Clinical Improvement may be assessed.","Day 7",{"measure":24,"description":25,"timeFrame":12},"Organ support free days","the number of days between enrollment and hospital discharge or day 28 that the participant did not receive support for some organ (lungs, kidneys, etc.)",{"measure":27,"description":28,"timeFrame":12},"The Sequential Organ Failure Assessment (SOFA) score - Day 28","The SOFA score is one of the most widely used scoring systems in critically ill patients and has also been validated in hospitalized patients with suspected infection outside the ICU. This score assesses organ dysfunction across 6 organ systems. To facilitate use of the SOFA score across a broad range of sites, including those in low- and-middle income countries (LMICs), SpO2 may be substituted for PaO2, and the presence of scleral icterus or jaundice may be substituted for serum bilirubin level . Only clinically available data will be used to calculate SOFA scores. Laboratory tests will not be completed by the study to calculate SOFA scores.",null,{"allocation":29,"interventionModel":29,"interventionModelDescription":29,"primaryPurpose":29,"observationalModel":31,"timePerspective":32,"maskingInfo":29},"COHORT","PROSPECTIVE","Participants will be enrolled at study sites globally. Study personnel at the enrolling site will confirm eligibility and obtain consent prior to beginning study procedures. Signing of the informed consent document signifies study entry and Study Day 0. The study population includes adult patients admitted to a hospital with a suspected or confirmed acute infection. All participants will meet the eligibility criteria below. Specific studies executed with this master protocol may narrow the eligibility criteria to a more specific population (that is, a subset of patients who meet the eligibility criteria in this overarching protocol).",[35],{"label":36,"type":29,"description":37,"interventionNames":38},"Study group","The study population includes adult patients admitted to a hospital with a suspected or confirmed acute infection.",[39],"Other: No intervention",[41],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":29},"No intervention","This is an observational study",[36],[46],{"name":47,"affiliation":5,"role":48},"Cavan Reilly, PhD","PRINCIPAL_INVESTIGATOR",[50],{"name":51,"role":52,"phone":53,"phoneExt":29,"email":54},"Rebecca Schoenecker","CONTACT","612-624-9644","webe0376@umn.edu",[56,74,86,97,111,125,139,151,164,175,187,198,206,218,229,241,253,265,276,288,300,316,326,340,351,362,374,386,397,408,419,429,440,453,466,481,494,505,518,534,542,554,568,579,592,605,613,625,638,649,663,676,688,698,711,724],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Banner University Medical Center Tucson","RECRUITING","Tucson","Arizona","85719","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-110.92648,32.22174,{"lat":68,"lon":67},[71],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},"Nashville ICC","icsarinash@strive-network.org",{"facility":75,"status":58,"city":76,"state":77,"zip":78,"country":62,"countryCode":63,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Stanford University Hospital & Clinics (Site 203-003)","Palo Alto","California","94305",{"type":65,"coordinates":80},[81,82],-122.14302,37.44188,{"lat":82,"lon":81},[85],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":87,"status":58,"city":88,"state":77,"zip":89,"country":62,"countryCode":63,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"UCSF Medical Center (Site 203-001)","San Francisco","94143",{"type":65,"coordinates":91},[92,93],-122.41942,37.77493,{"lat":93,"lon":92},[96],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":98,"status":58,"city":99,"state":100,"zip":101,"country":62,"countryCode":63,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Orlando VA Medical Center (074-032)","Orlando","Florida","32827",{"type":65,"coordinates":103},[104,105],-81.37924,28.53834,{"lat":105,"lon":104},[108],{"name":109,"role":52,"phone":29,"phoneExt":29,"email":110},"Washington ICC","icsariwdc@strive-network.org",{"facility":112,"status":58,"city":113,"state":114,"zip":115,"country":62,"countryCode":63,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"University of Illinois at Chicago (Site 008-012)","Chicago","Illinois","60612",{"type":65,"coordinates":117},[118,119],-87.65005,41.85003,{"lat":119,"lon":118},[122],{"name":123,"role":52,"phone":29,"phoneExt":29,"email":124},"Hennepin ICC","icsarihenn@strive-network.org",{"facility":126,"status":58,"city":127,"state":128,"zip":129,"country":62,"countryCode":63,"cosmosGeoPoint":130,"geoPoint":134,"contacts":135},"Lutheran Medical Group","Fort Wayne","Indiana","46804",{"type":65,"coordinates":131},[132,133],-85.12886,41.1306,{"lat":133,"lon":132},[136],{"name":137,"role":52,"phone":29,"phoneExt":29,"email":138},"New York ICC","icsariny@strive-network.org",{"facility":140,"status":58,"city":141,"state":142,"zip":143,"country":62,"countryCode":63,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"University of Kansas Medical Center (Site 080-044)","Kansas City","Kansas","66160",{"type":65,"coordinates":145},[146,147],-94.62746,39.11417,{"lat":147,"lon":146},[150],{"name":123,"role":52,"phone":29,"phoneExt":29,"email":124},{"facility":5,"status":152,"city":153,"state":154,"zip":155,"country":62,"countryCode":63,"cosmosGeoPoint":156,"geoPoint":160,"contacts":161},"NOT_YET_RECRUITING","Minneapolis","Minnesota","55414",{"type":65,"coordinates":157},[158,159],-93.26384,44.97997,{"lat":159,"lon":158},[162],{"name":47,"role":52,"phone":29,"phoneExt":29,"email":163},"Reill017@umn.edu",{"facility":165,"status":58,"city":166,"state":154,"zip":167,"country":62,"countryCode":63,"cosmosGeoPoint":168,"geoPoint":172,"contacts":173},"Mayo Clinic (Site 054-001)","Rochester","55905",{"type":65,"coordinates":169},[170,171],-92.4699,44.02163,{"lat":171,"lon":170},[174],{"name":123,"role":52,"phone":29,"phoneExt":29,"email":124},{"facility":176,"status":58,"city":177,"state":178,"zip":179,"country":62,"countryCode":63,"cosmosGeoPoint":180,"geoPoint":184,"contacts":185},"University of Nebraska Medical Center (Site 080-045)","Omaha","Nebraska","68198-5400",{"type":65,"coordinates":181},[182,183],-95.94043,41.25626,{"lat":183,"lon":182},[186],{"name":123,"role":52,"phone":29,"phoneExt":29,"email":124},{"facility":188,"status":58,"city":189,"state":189,"zip":190,"country":62,"countryCode":63,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"New York University Langone Health (301-013)","New York","10016",{"type":65,"coordinates":192},[193,194],-74.00597,40.71427,{"lat":194,"lon":193},[197],{"name":137,"role":52,"phone":29,"phoneExt":29,"email":138},{"facility":199,"status":58,"city":189,"state":189,"zip":200,"country":62,"countryCode":63,"cosmosGeoPoint":201,"geoPoint":203,"contacts":204},"Mount Sinai Medical Center (Site 301-012)","11234",{"type":65,"coordinates":202},[193,194],{"lat":194,"lon":193},[205],{"name":137,"role":52,"phone":29,"phoneExt":29,"email":138},{"facility":207,"status":58,"city":208,"state":209,"zip":210,"country":62,"countryCode":63,"cosmosGeoPoint":211,"geoPoint":215,"contacts":216},"Duke University (301-006)","Durham","North Carolina","27710",{"type":65,"coordinates":212},[213,214],-78.89862,35.99403,{"lat":214,"lon":213},[217],{"name":137,"role":52,"phone":29,"phoneExt":29,"email":138},{"facility":219,"status":58,"city":220,"state":209,"zip":221,"country":62,"countryCode":63,"cosmosGeoPoint":222,"geoPoint":226,"contacts":227},"Wake Forest Baptist Health (210-001)","Winston-Salem","27157",{"type":65,"coordinates":223},[224,225],-80.24422,36.09986,{"lat":225,"lon":224},[228],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":230,"status":58,"city":231,"state":232,"zip":233,"country":62,"countryCode":63,"cosmosGeoPoint":234,"geoPoint":238,"contacts":239},"Cleveland Clinic Foundation (Site 207-001)","Cleveland","Ohio","44195",{"type":65,"coordinates":235},[236,237],-81.69541,41.4995,{"lat":237,"lon":236},[240],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":242,"status":58,"city":243,"state":244,"zip":245,"country":62,"countryCode":63,"cosmosGeoPoint":246,"geoPoint":250,"contacts":251},"Vanderbilt University Medical Center (Site 212-001)","Nashville","Tennessee","37232",{"type":65,"coordinates":247},[248,249],-86.78444,36.16589,{"lat":249,"lon":248},[252],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":254,"status":58,"city":255,"state":256,"zip":257,"country":62,"countryCode":63,"cosmosGeoPoint":258,"geoPoint":262,"contacts":263},"UT Southwestern Medical Center (084-001)","Dallas","Texas","75390",{"type":65,"coordinates":259},[260,261],-96.80667,32.78306,{"lat":261,"lon":260},[264],{"name":109,"role":52,"phone":29,"phoneExt":29,"email":110},{"facility":266,"status":58,"city":267,"state":256,"zip":268,"country":62,"countryCode":63,"cosmosGeoPoint":269,"geoPoint":273,"contacts":274},"MEDVAMC (Site 074-006)","Houston","77030-4211",{"type":65,"coordinates":270},[271,272],-95.36327,29.76328,{"lat":272,"lon":271},[275],{"name":109,"role":52,"phone":29,"phoneExt":29,"email":110},{"facility":277,"status":58,"city":278,"state":279,"zip":280,"country":62,"countryCode":63,"cosmosGeoPoint":281,"geoPoint":285,"contacts":286},"Intermountain Medical Center (Site 211-001)","Murray","Utah","84107",{"type":65,"coordinates":282},[283,284],-111.88799,40.66689,{"lat":284,"lon":283},[287],{"name":72,"role":52,"phone":29,"phoneExt":29,"email":73},{"facility":289,"status":58,"city":290,"state":291,"zip":292,"country":62,"countryCode":63,"cosmosGeoPoint":293,"geoPoint":297,"contacts":298},"West Virginia University Medicine (301-023)","Morgantown","West Virginia","26506",{"type":65,"coordinates":294},[295,296],-79.9559,39.62953,{"lat":296,"lon":295},[299],{"name":137,"role":52,"phone":29,"phoneExt":29,"email":138},{"facility":301,"status":58,"city":302,"state":303,"zip":304,"country":305,"countryCode":306,"cosmosGeoPoint":307,"geoPoint":311,"contacts":312},"Instituto Medico Platense (611-025)","La Plata","Buenos Aires","B1900AVG","Argentina","AR",{"type":65,"coordinates":308},[309,310],-57.95442,-34.92126,{"lat":310,"lon":309},[313],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},"Sydney ICC","icsarisyd@strive-network.org",{"facility":317,"status":58,"city":303,"state":29,"zip":318,"country":305,"countryCode":306,"cosmosGeoPoint":319,"geoPoint":323,"contacts":324},"Hospital General de Agudos JM Ramos Mejia (Site 611-001)","C1221ADC",{"type":65,"coordinates":320},[321,322],-58.37723,-34.61315,{"lat":322,"lon":321},[325],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":327,"status":58,"city":328,"state":329,"zip":330,"country":331,"countryCode":332,"cosmosGeoPoint":333,"geoPoint":337,"contacts":338},"Royal Prince Alfred Hospital (612-056)","Camperdown","New South Wales","2050","Australia","AU",{"type":65,"coordinates":334},[335,336],151.17642,-33.88965,{"lat":336,"lon":335},[339],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":341,"status":58,"city":342,"state":329,"zip":343,"country":331,"countryCode":332,"cosmosGeoPoint":344,"geoPoint":348,"contacts":349},"St. Vincent's Hospital (612-002)","Sydney","2010",{"type":65,"coordinates":345},[346,347],151.20732,-33.86785,{"lat":347,"lon":346},[350],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":352,"status":58,"city":353,"state":329,"zip":354,"country":331,"countryCode":332,"cosmosGeoPoint":355,"geoPoint":359,"contacts":360},"Westmead Hospital (Site 612-058)","Westmead","2145",{"type":65,"coordinates":356},[357,358],150.98768,-33.80383,{"lat":358,"lon":357},[361],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":363,"status":58,"city":364,"state":365,"zip":366,"country":331,"countryCode":332,"cosmosGeoPoint":367,"geoPoint":371,"contacts":372},"Royal Brisbane and Women's Hospital (Site 612-055)","Brisbane","Queensland","4029",{"type":65,"coordinates":368},[369,370],153.02809,-27.46794,{"lat":370,"lon":369},[373],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":375,"status":58,"city":376,"state":377,"zip":378,"country":331,"countryCode":332,"cosmosGeoPoint":379,"geoPoint":383,"contacts":384},"Monash Health (612-009)","Clayton","Victoria","3168",{"type":65,"coordinates":380},[381,382],145.11667,-37.91667,{"lat":382,"lon":381},[385],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":387,"status":58,"city":388,"state":377,"zip":389,"country":331,"countryCode":332,"cosmosGeoPoint":390,"geoPoint":394,"contacts":395},"Austin Health (Site 612-020)","Heidelberg","3084",{"type":65,"coordinates":391},[392,393],145.06667,-37.75,{"lat":393,"lon":392},[396],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":398,"status":58,"city":399,"state":377,"zip":400,"country":331,"countryCode":332,"cosmosGeoPoint":401,"geoPoint":405,"contacts":406},"The Alfred Hospital (Site 612-017)","Melbourne","3004",{"type":65,"coordinates":402},[403,404],144.96332,-37.814,{"lat":404,"lon":403},[407],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":409,"status":58,"city":410,"state":377,"zip":411,"country":331,"countryCode":332,"cosmosGeoPoint":412,"geoPoint":416,"contacts":417},"The Royal Melbourne Hospital (612-025)","Parkville","3050",{"type":65,"coordinates":413},[414,415],144.95,-37.78333,{"lat":415,"lon":414},[418],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":420,"status":58,"city":421,"state":29,"zip":29,"country":331,"countryCode":332,"cosmosGeoPoint":422,"geoPoint":426,"contacts":427},"Liverpool Hospital","Liverpool",{"type":65,"coordinates":423},[424,425],150.92588,-33.91938,{"lat":425,"lon":424},[428],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":430,"status":58,"city":431,"state":29,"zip":432,"country":331,"countryCode":332,"cosmosGeoPoint":433,"geoPoint":437,"contacts":438},"Fiona Stanley Hospital","Murdoch","6150",{"type":65,"coordinates":434},[435,436],115.83757,-32.06987,{"lat":436,"lon":435},[439],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":441,"status":58,"city":442,"state":442,"zip":443,"country":444,"countryCode":445,"cosmosGeoPoint":446,"geoPoint":450,"contacts":451},"Associaco Beneficente Siria - HCor (649-203)","São Paulo","04004-030","Brazil","BR",{"type":65,"coordinates":447},[448,449],-46.63611,-23.5475,{"lat":449,"lon":448},[452],{"name":109,"role":52,"phone":29,"phoneExt":29,"email":110},{"facility":454,"status":58,"city":455,"state":29,"zip":29,"country":456,"countryCode":29,"cosmosGeoPoint":457,"geoPoint":461,"contacts":462},"CERMIPA (Site 403-001)","Abidjan","Côte d’Ivoire",{"type":65,"coordinates":458},[459,460],-4.00167,5.35444,{"lat":460,"lon":459},[463],{"name":464,"role":52,"phone":29,"phoneExt":29,"email":465},"ANRS ICC","icsarianrs@strive-network.org",{"facility":467,"status":58,"city":468,"state":29,"zip":469,"country":470,"countryCode":471,"cosmosGeoPoint":472,"geoPoint":476,"contacts":477},"Rigshospitalet, CHIP (625-006)","Copenhagen","2100","Denmark","DK",{"type":65,"coordinates":473},[474,475],12.56553,55.67594,{"lat":475,"lon":474},[478],{"name":479,"role":52,"phone":29,"phoneExt":29,"email":480},"Copenhagen ICC","icsaricph@strive-network.org",{"facility":482,"status":58,"city":483,"state":29,"zip":484,"country":485,"countryCode":486,"cosmosGeoPoint":487,"geoPoint":491,"contacts":492},"Hospices Civiles de Lyon (631-033)","Lyon","69002","France","FR",{"type":65,"coordinates":488},[489,490],4.84789,45.74906,{"lat":490,"lon":489},[493],{"name":464,"role":52,"phone":29,"phoneExt":29,"email":465},{"facility":495,"status":58,"city":496,"state":29,"zip":497,"country":485,"countryCode":486,"cosmosGeoPoint":498,"geoPoint":502,"contacts":503},"Hospital St Louis (631-019)","Paris","75010",{"type":65,"coordinates":499},[500,501],2.3488,48.85341,{"lat":501,"lon":500},[504],{"name":464,"role":52,"phone":29,"phoneExt":29,"email":465},{"facility":506,"status":58,"city":507,"state":29,"zip":508,"country":509,"countryCode":510,"cosmosGeoPoint":511,"geoPoint":515,"contacts":516},"Klinik I fur Innere Medizin der Universitat zu Koln (622-008)","Cologne","50937","Germany","DE",{"type":65,"coordinates":512},[513,514],6.95,50.93333,{"lat":514,"lon":513},[517],{"name":479,"role":52,"phone":29,"phoneExt":29,"email":480},{"facility":519,"status":58,"city":520,"state":521,"zip":522,"country":523,"countryCode":524,"cosmosGeoPoint":525,"geoPoint":529,"contacts":530},"Evangelismos General Hospital (Site 635-020)","Athens","Attica","10676","Greece","GR",{"type":65,"coordinates":526},[527,528],23.72784,37.98376,{"lat":528,"lon":527},[531],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},"London ICC","icsarilon@strive-network.org",{"facility":535,"status":58,"city":520,"state":521,"zip":536,"country":523,"countryCode":524,"cosmosGeoPoint":537,"geoPoint":539,"contacts":540},"3rd Dept of Medicine, Medical School (Site 635-022)","11527",{"type":65,"coordinates":538},[527,528],{"lat":528,"lon":527},[541],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},{"facility":543,"status":58,"city":544,"state":29,"zip":29,"country":545,"countryCode":546,"cosmosGeoPoint":547,"geoPoint":551,"contacts":552},"SMIT du CHU de Donka","Conakry","Guinea","GN",{"type":65,"coordinates":548},[549,550],-13.67729,9.53795,{"lat":550,"lon":549},[553],{"name":464,"role":52,"phone":29,"phoneExt":29,"email":465},{"facility":555,"status":58,"city":556,"state":557,"zip":558,"country":559,"countryCode":560,"cosmosGeoPoint":561,"geoPoint":565,"contacts":566},"Fujita Health University Hospital","Toyoake","Aichi-ken","470-1192","Japan","JP",{"type":65,"coordinates":562},[563,564],136.99931,35.038,{"lat":564,"lon":563},[567],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":569,"status":58,"city":570,"state":29,"zip":571,"country":559,"countryCode":560,"cosmosGeoPoint":572,"geoPoint":576,"contacts":577},"Japan Institute for Health Security","Tokyo","162-8655",{"type":65,"coordinates":573},[574,575],139.69171,35.6895,{"lat":575,"lon":574},[578],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":580,"status":58,"city":581,"state":581,"zip":582,"country":583,"countryCode":584,"cosmosGeoPoint":585,"geoPoint":589,"contacts":590},"Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (653-001)","Mexico City","14080","Mexico","MX",{"type":65,"coordinates":586},[587,588],-99.12766,19.42847,{"lat":588,"lon":587},[591],{"name":123,"role":52,"phone":29,"phoneExt":29,"email":124},{"facility":593,"status":58,"city":594,"state":29,"zip":595,"country":596,"countryCode":597,"cosmosGeoPoint":598,"geoPoint":602,"contacts":603},"Hospital Nacional Guillermo Almenara Irigoyen (Site 651-003)","Lima","15033","Peru","PE",{"type":65,"coordinates":599},[600,601],-77.02824,-12.04318,{"lat":601,"lon":600},[604],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":110},{"facility":606,"status":58,"city":594,"state":29,"zip":607,"country":596,"countryCode":597,"cosmosGeoPoint":608,"geoPoint":610,"contacts":611},"Instituto Nacional de Entermadades Neoplasicas (Site 651-012","15038",{"type":65,"coordinates":609},[600,601],{"lat":601,"lon":600},[612],{"name":109,"role":52,"phone":29,"phoneExt":29,"email":110},{"facility":614,"status":58,"city":615,"state":29,"zip":616,"country":615,"countryCode":617,"cosmosGeoPoint":618,"geoPoint":622,"contacts":623},"Tan Tock Seng Hospital","Singapore","308443","SG",{"type":65,"coordinates":619},[620,621],103.85007,1.28967,{"lat":621,"lon":620},[624],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":626,"status":58,"city":627,"state":628,"zip":629,"country":630,"countryCode":29,"cosmosGeoPoint":631,"geoPoint":635,"contacts":636},"Seoul National University Bundang Hospital","Seongnam-si","Gyeonggi-do","13620","South Korea",{"type":65,"coordinates":632},[633,634],127.13778,37.43861,{"lat":634,"lon":633},[637],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":639,"status":58,"city":640,"state":29,"zip":641,"country":630,"countryCode":29,"cosmosGeoPoint":642,"geoPoint":646,"contacts":647},"Seoul St. Mary's Hospital","Seoul","06591",{"type":65,"coordinates":643},[644,645],126.9784,37.566,{"lat":645,"lon":644},[648],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":650,"status":58,"city":651,"state":652,"zip":653,"country":654,"countryCode":655,"cosmosGeoPoint":656,"geoPoint":660,"contacts":661},"Hospital Universitari Germans Trias i Pujol (Site 626-003)","Badalona","Barcelona","08916","Spain","ES",{"type":65,"coordinates":657},[658,659],2.24741,41.45004,{"lat":659,"lon":658},[662],{"name":479,"role":52,"phone":29,"phoneExt":29,"email":480},{"facility":664,"status":58,"city":665,"state":29,"zip":666,"country":667,"countryCode":668,"cosmosGeoPoint":669,"geoPoint":673,"contacts":674},"Chulalongkorn University and The HIV-NAT (Site 613-001)","Bangkok","10330","Thailand","TH",{"type":65,"coordinates":670},[671,672],100.50144,13.75398,{"lat":672,"lon":671},[675],{"name":314,"role":52,"phone":29,"phoneExt":29,"email":315},{"facility":677,"status":58,"city":678,"state":29,"zip":29,"country":679,"countryCode":680,"cosmosGeoPoint":681,"geoPoint":685,"contacts":686},"MRC\u002FUVRI & LSHTM Uganda Research Unit (Site 634-601)","Entebbe","Uganda","UG",{"type":65,"coordinates":682},[683,684],32.47949,0.05621,{"lat":684,"lon":683},[687],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},{"facility":689,"status":58,"city":690,"state":29,"zip":29,"country":679,"countryCode":680,"cosmosGeoPoint":691,"geoPoint":695,"contacts":696},"Lira Regional Referral Hospital (Site 634-605)","Lira",{"type":65,"coordinates":692},[693,694],32.89985,2.2499,{"lat":694,"lon":693},[697],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},{"facility":699,"status":58,"city":700,"state":29,"zip":701,"country":702,"countryCode":703,"cosmosGeoPoint":704,"geoPoint":708,"contacts":709},"Central City Clinical Hospital of Ivano-Frankivsk City Council (627-302)","Ivano-Frankivsk","76018","Ukraine","UA",{"type":65,"coordinates":705},[706,707],24.71248,48.92312,{"lat":707,"lon":706},[710],{"name":479,"role":52,"phone":29,"phoneExt":29,"email":480},{"facility":712,"status":58,"city":713,"state":29,"zip":714,"country":715,"countryCode":716,"cosmosGeoPoint":717,"geoPoint":721,"contacts":722},"Royal Free Hospital (Site 634-006)","London","NW3 2QG","United Kingdom","UK",{"type":65,"coordinates":718},[719,720],-0.12574,51.50853,{"lat":720,"lon":719},[723],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},{"facility":725,"status":58,"city":726,"state":29,"zip":29,"country":727,"countryCode":728,"cosmosGeoPoint":729,"geoPoint":733,"contacts":734},"Parirenyatwa General Hospital","Harare","Zimbabwe","ZW",{"type":65,"coordinates":730},[731,732],31.05337,-17.82772,{"lat":732,"lon":731},[735],{"name":532,"role":52,"phone":29,"phoneExt":29,"email":533},{"type":737,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100598277","an-international-observational-study-of-adults-with-acute-infection-100598277",false,"NCT07069400","An International Observational Study of Adults With Acute Infection","Inclusion Criteria:\n\n* Age ≥18 years old\n* Admitted to hospital (or in an emergency department with anticipated hospital admission) for the management of a suspected or confirmed acute infectious disease.\n* Onset of symptoms of an infectious disease within the past 30 days.\n* Informed consent for study participation by the participant or a surrogate decision maker if the participant lacks capacity for consent.\n\nExclusion Criteria:\n\n* Current imprisonment (this does not include quarantine for an infectious disease).\n* Patient undergoing comfort care measures only such that treatment focuses on end- of-life symptom management over prolongation of life.\n* Expected inability or unwillingness to participate in study procedures.\n* In the opinion of the investigator, participation in the study is not in the best interest of the patient.","ALL","18 Years",{"count":747,"type":748},1500,"ESTIMATED","OBSERVATIONAL","Prospective, longitudinal studies of people with acute infections are essential to understand risk factors, clinical manifestations, pathobiology, and management strategies. Observational studies can provide data necessary to select interventions and strategies for testing in clinical trials and to develop key design features of trials. Observational studies can be particularly important for establishing an early knowledge base after emergence of a new pathogen, as illustrated by the recent emergence of influenza A (H1N1), SARS-CoV-2, and Mpox. This observational study protocol describes collection of data and biospecimens from sites across the world for characterizing acute infections in hospitalized patients. The protocol is designed to study respiratory infections, infections outside the respiratory tract, established infectious diseases, and emerging infectious diseases. Data generated in this study will be used to efficiently characterize acute infectious diseases and plan future clinical trials.",[752],"Infectious Disease","2026-08-26",{"date":755,"type":756},"2026-08-27","ACTUAL",{"date":758,"type":756},"2025-08-25",{"date":760,"type":748},"2027-06-08",{"name":5,"class":6},56]