[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649344":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":31,"locations":39,"responsibleParty":55,"collaborators":10,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":82,"overallStatus":85,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Oklahoma","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Diagnosed Malignancies",null,"Participants in this group either have a newly diagnosed, untreated cancer or a pre-existing cancer diagnosis but are not currently receiving anticancer therapy. Participants with a pre-existing diagnosis must not have received any anticancer treatment within the previous month.",[13],"Device: Proton Transfer Reaction Mass Spectrometry Analysis",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Control Group","Participants in this control group have no current or prior diagnosis of a malignancy.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Proton Transfer Reaction Mass Spectrometry Analysis","This is a noninvasive intervention. Participants will be asked to provide a breath sample using a disposable mouthpiece equipped with a saliva\u002Fmoisture trap and a non-rebreathing valve. Breath samples will be collected through normal, steady exhalation. The entire breath collection process is expected to take no more than 30 minutes to complete.",[9,15],[25],"PTR-MS",[27],{"name":28,"affiliation":29,"role":30},"Nirmal Choradia, MD","University of Oklahoma - Stephenson Cancer Center","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":10,"email":36},"Lead Onco Nurse","CONTACT","405-271-8777","SCC-IIT-Office@ouhsc.edu",{"name":28,"role":34,"phone":10,"phoneExt":10,"email":38},"Nirmal-Choradia@ouhsc.edu",[40],{"facility":41,"status":10,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"OU Health Stephenson Cancer Center","Oklahoma City","Oklahoma","73117","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-97.51643,35.46756,{"lat":51,"lon":50},[54],{"name":28,"role":34,"phone":10,"phoneExt":10,"email":38},{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100649344","analysis-of-breath-volatile-organic-compounds-using-mass-spectrometry-100649344",false,"NCT07732686","Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry","Breath Volatile Organic Compounds (VOC) Analysis Using Proton Transfer Reaction Mass Spectrometry (PTR-MS)","Inclusion Criteria:\n\n* Age ≥ 18 at the time of consent. Male and female patients to be tested.\n* Capable of understanding written and\u002For spoken English language.\n* Able to provide informed consent.\n* Cancer of any type.\n* Newly diagnosed cancer and untreated or established diagnosis of cancer. For established cancer patients, no active anti-cancer treatment for more than one month (reasons for no treatment are such as relapse, progression of cancer, refractory, or intolerance to treatment etc.)\n\nExclusion Criteria:\n\n* Under the age of 18.\n* Anticipated inability to complete breath sampling procedure.\n* Unable to provide informed consent.\n* Pregnant women\n* Active respiratory infection symptoms\n* Recent use of antibiotics\n* Difficulty in performing coached exhalation\n* Individuals who are unable to follow the instructions\n* Cancer patients who are on active treatment for cancer or have received cancer treatment within one month",true,"ALL","18 Years",{"count":68,"type":69},2000,"ESTIMATED","OBSERVATIONAL","The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.",[73,74,75,76,77,78,79,80,81],"Pancreas Cancer","Hepatocellular Carcinoma","Lung Cancer","Ovarian Cancer","Breast Cancer","Head and Neck Cancer","Colon Cancer","Bladder Cancer","Other Cancer",[83,25,84],"VOC","ML","NOT_YET_RECRUITING","2026-07-23",{"date":88,"type":89},"2026-07-29","ACTUAL",{"date":91,"type":69},"2026-10",{"date":93,"type":69},"2029-10",{"name":5,"class":6},1]