[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656749":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":27,"studyPopulation":27,"armGroups":34,"interventions":40,"overallOfficials":27,"centralContacts":44,"locations":50,"responsibleParty":65,"collaborators":27,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":27,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":27,"studyType":82,"phases":83,"briefSummary":84,"conditions":85,"keywords":27,"overallStatus":52,"whyStopped":27,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Chungnam National University Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":27},[9],{"measure":10,"description":11,"timeFrame":12},"Change from Baseline in Cerebrospinal Fluid Flow Velocity (cm\u002Fs) at 30 Minutes Post-Procedure","Assessment of cerebrospinal fluid flow parameters before and after the procedure.","Baseline (Pre-intervention) and 30 minutes post-intervention",[14,18,21,24],{"measure":15,"description":16,"timeFrame":17},"Change from Baseline in 10-Meter Walk Test (10MWT) Time at 6 Hours and 24 Hours Post-Procedure","Completion time during the 10-meter walk test, measured in seconds.","Baseline, 6 hours post-procedure, and 24 hours post-procedure",{"measure":19,"description":20,"timeFrame":17},"Change from Baseline in 10-Meter Walk Test Step Count at 6 Hours and 24 Hours Post-Procedure","Number of steps taken during the 10-meter walk test, measured in steps.",{"measure":22,"description":23,"timeFrame":17},"Change from Baseline in Timed Up and Go (TUG) Test Time at 6 Hours and 24 Hours Post-Procedure","Completion time during the 3-meter TUG test, measured in seconds.",{"measure":25,"description":26,"timeFrame":17},"Change from Baseline in Cognitive Timed Up and Go (Cognitive TUG) Test Time at 6 Hours and 24 Hours Post-Procedure","Completion time during the 3-meter Cognitive TUG test while performing a dual task, measured in seconds.",null,{"allocation":29,"interventionModel":30,"interventionModelDescription":27,"primaryPurpose":31,"observationalModel":27,"timePerspective":27,"maskingInfo":32},"NA","SINGLE_GROUP","TREATMENT",{"masking":33,"maskingDescription":27,"whoMasked":27},"NONE",[35],{"label":36,"type":37,"description":27,"interventionNames":38},"Cerebrospinal fluid drainge","EXPERIMENTAL",[39],"Procedure: Cerebrospinal fluid drainge",[41],{"type":42,"name":36,"description":36,"armGroupLabels":43,"otherNames":27},"PROCEDURE",[36],[45],{"name":46,"role":47,"phone":48,"phoneExt":27,"email":49},"Eungseok Oh","CONTACT","82-42-280-7800","doctor_oh@daum.net",[51],{"facility":5,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":27,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"RECRUITING","Daejeon","Jung-gu","35015","South Korea",{"type":58,"coordinates":59},"Point",[60,61],127.38493,36.34913,{"lat":61,"lon":60},[64],{"name":46,"role":47,"phone":48,"phoneExt":27,"email":49},{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Hee Jin Chang","Professor","100656749","analysis-of-cerebrospinal-fluid-dynamics-in-normal-pressure-hydrocephalus-100656749",false,"NCT07831044","Analysis of Cerebrospinal Fluid Dynamics in Normal Pressure Hydrocephalus","Analysis of Cerebrospinal Fluid Dynamics in Patients With Normal Pressure Hydrocephalus Using Magnetic Resonance Imaging","Inclusion Criteria:\n\n* Patients presenting with clinical symptoms consistent with normal pressure hydrocephalus (presence of gait disturbance accompanied by at least one of the following: cognitive impairment or urinary dysfunction)\n* Evans' ratio ≥ 0.3 on brain MRI\n\nExclusion Criteria:\n\n* Patients who cannot undergo CSF drainage due to structural abnormalities of the lumbar spine\n* Contraindications to lumbar puncture and CSF drainage (e.g., local infection at the puncture site, suspected elevated intracranial pressure, platelet count \\\u003C 40,000\u002FµL, or coagulopathy)\n* Coexisting neurological disorders that can also cause gait disturbance, such as Parkinson's disease, atypical parkinsonian syndromes, or vascular parkinsonism\n* Contraindications to MRI (e.g., presence of cardiac pacemakers, implantable defibrillators, or other non-MRI-compatible implantable medical devices)","ALL","55 Years","80 Years",{"count":80,"type":81},22,"ESTIMATED","INTERVENTIONAL",[29],"This study aims to evaluate whether phase-contrast magnetic resonance imaging (MRI)-based cerebrospinal fluid (CSF) flow dynamics can improve the diagnosis and prognostic assessment of normal pressure hydrocephalus (NPH). In addition, the study investigates how changes in CSF flow parameters before and after CSF diversion procedures are associated with clinical improvement.",[86],"Normal Pressure Hydrocephalus","2026-09-15",{"date":89,"type":90},"2026-09-21","ACTUAL",{"date":92,"type":90},"2025-09-11",{"date":94,"type":81},"2028-12",{"name":5,"class":6},1]