[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658674":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":16,"studyPopulation":17,"armGroups":18,"interventions":13,"overallOfficials":13,"centralContacts":25,"locations":13,"responsibleParty":31,"collaborators":13,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":13,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":13,"enrollmentInfo":45,"targetDuration":13,"studyType":48,"phases":13,"briefSummary":49,"conditions":50,"keywords":13,"overallStatus":52,"whyStopped":13,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":13},{"fullName":5,"class":6},"Cairo University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Prevalence of apical periodontitis","Presence or absence of apical periodontitis assessed by digital panoramic radiographic examination using binary scoring based on the presence of periapical radiolucency.","During the 6-month study\u002Frecruitment period.",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":6,"timePerspective":15,"maskingInfo":13},"CROSS_SECTIONAL","Apical periodontitis is an inflammatory disease of the periapical tissues that develops as a consequence of endodontic infection. Diabetes mellitus has been associated with an increased prevalence of apical periodontitis, although the available evidence remains limited and inconsistent. In addition, the relationship between glycemic control and apical periodontitis remains unclear, and population-specific data in Egypt are limited.\n\nThis observational cross-sectional study will assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and evaluate the association between glycemic control and apical periodontitis. Participants will be recruited from outpatient dental clinics of the Endocrine and Diabetes Center in Cairo, Egypt, in collaboration with the Department of Endodontics, Faculty of Dentistry, Cairo university.\n\nEligible participants will be Egyptian males and females aged 21 years or older with at least eight teeth present. Participants will undergo standardized clinical oral examination, digital panoramic radiographic examination, and measurement of glycated hemoglobin (HbA1c). Apical periodontitis will be assessed radiographically based on the presence or absence of periapical radiolucency. Participants will be classified into diabetic and non-diabetic groups according to HbA1c levels.\n\nThe primary objective is to assess the prevalence of apical periodontitis in diabetic and non-diabetic patients. The secondary objective is to evaluate the association between HbA1c levels and the presence of apical periodontitis. The planned sample size is 88 participants, with 44 participants in each group.","Adult Egyptian male and female patients aged 21 years or older with at least 8 teeth, recruited from outpatient dental clinics at the Faculty of Dentistry, Cairo University and the Endocrine and Diabetes Center, Cairo, Egypt. Participants will be classified into diabetic and non-diabetic groups based on their measured HbA1c levels.",[19,22],{"label":20,"type":13,"description":21,"interventionNames":13},"Group 1: diabetic participants","Participants with HbA1c ≥6.5%",{"label":23,"type":13,"description":24,"interventionNames":13},"Group 2: non-diabetic participants","Participants with HbA1c \\\u003C6.5%.",[26],{"name":27,"role":28,"phone":29,"phoneExt":13,"email":30},"Yara Yousif Kairi","CONTACT","+201555003176","Yara.kairi@dentistry.cu.edu.eg",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Yara Yousif Abdalla Kairi","Master's student","100658674","apical-periodontitis-and-glycemic-control-in-diabetic-and-non-diabetic-egyptian-sub-population-100658674",false,"NCT07856186","Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population","Prevalence of Apical Periodontitis and it's Association With Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population: A Cross-sectional Study","Inclusion Criteria:\n\n* Adult Egyptian males and females\n* 21 years or older\n* At least 8 teeth present\n* Willing to undergo clinical and radiographic examination, HbA1c measurement, -Willing to provide informed consent.\n\nExclusion Criteria:\n\n* Participants younger than 21 years\n* fewer than 8 teeth\n* Those who refuse clinical or radiographic examination\n* Patients with systemic diseases other than diabetes that may affect oral or periapical health.",true,"ALL","21 Years",{"count":46,"type":47},88,"ESTIMATED","OBSERVATIONAL","This observational cross-sectional study aims to assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and to evaluate its association with glycemic control measured by glycated hemoglobin (HbA1c). Participants will undergo clinical examination, digital panoramic radiographic assessment, and HbA1c measurement.",[51],"Apical Periodontitis","NOT_YET_RECRUITING","2026-09-30",{"date":55,"type":56},"2026-10-02","ACTUAL",{"date":58,"type":47},"2026-10-05",{"date":60,"type":47},"2027-05-05",{"name":5,"class":6}]