[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648051":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":32,"locations":31,"responsibleParty":38,"collaborators":31,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":31,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":31,"enrollmentInfo":51,"targetDuration":31,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":66,"whyStopped":31,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":31},{"fullName":5,"class":6},"Rambam Health Care Campus","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Apixaban","EXPERIMENTAL","Apixaban. 2.5 mg administered orally twice a day",[13],"Drug: Apixaban",{"label":15,"type":16,"description":17,"interventionNames":18},"Enoxaparin","ACTIVE_COMPARATOR","Enoxaparin. 40 mg (or 60 mg for weight \\> 91 kg) administered subcutaneously once a day",[19],"Drug: Enoxaparin",[21,26],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG",[9],[25],"eliquis",{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":29},"Enoxaparin 40 mg (or 60 mg for weight \\> 91 kg) administered subcutaneously once a day",[15],[30],"clexane",null,[33],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},"Nira Gridish","CONTACT","+972503027855","n_gridish@rambam.health.gov.il",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"SPONSOR_INVESTIGATOR","Ron Beloosesky MD","Head of the Gynecology and Obstetric Ultrasonography Unit.","100648051","apixaban-versus-enoxaparin-for-postpartum-venous-thromboembolism-prophylaxis-100648051",false,"NCT07716332","Apixaban Versus Enoxaparin for Postpartum Venous Thromboembolism Prophylaxis","Apixaban Versus Enoxaparin for Thromboprophylaxis After Delivery","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* After Vaginal or C\u002FS delivery.\n* Need prophylactic treatment in a preventive dose.\n* Presence of one or more high risk factors: Active infection, IBD, Heart disease, Type 1 diabetes with nephropathy, IV drug user, Surgical operation in Postpartum period, Emergency cesarean section.\n\nOR presence of 2 low risk factors: Age \\> 35, post-partum hemorrhage \\> 1000 ml, Cesarean section, Hysterectomy, BMI \\> 30, Multiparity- Third birth or more, Active Smoking, Obstetric complications in current pregnancy (including preeclampsia, preterm birth before 37 weeks, active infection including chorioamnionitis, prolonged labor over 24 hours), Twin birth, Immobility, Large varicose veins, Stillbirth\n\nExclusion Criteria:\n\n* Breast feeding.\n* Predispose to hypercoagulability\n* Familial history of VTE.\n* Antiphospholipid syndrome (APS).\n* Prior VTE.\n* Anticoagulant treatment before or during pregnancy.\n* BMI \\> 40\n* History of severe renal or hepatic disease.\n* Use of selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors.\n* Known diagnosis of bleeding dyscrasia (eg, von Willebrand disease).\n* Spinal\u002Fepidural hematoma or spinal puncture.\n* Active pathological bleeding or high risk of bleeding.\n* Hemoglobin \\> 9 mg\u002Fdl before the delivery.","FEMALE","18 Years",{"count":52,"type":53},150,"ESTIMATED","INTERVENTIONAL",[56],"NA","The purpose of this study is to compare the use of oral apixaban to subcutaneous enoxaparin for venous thromboembolism (VTE) prophylaxis in postpartum women at high risk for VTE. The primary goal is to evaluate medication adherence rates and patient satisfaction with the treatment.",[59,60],"Postpartum","DVT Prophylaxis",[62,63,64,65],"apixaban","enoxaparin","vte prophylaxis","postpartum","NOT_YET_RECRUITING","2026-07-20",{"date":69,"type":70},"2026-07-21","ACTUAL",{"date":72,"type":53},"2026-07-01",{"date":74,"type":53},"2027-04-01",{"name":40,"class":6}]