[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648178":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":56,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":26,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":84,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Sisli Hamidiye Etfal Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"GroupASPB + PIPB Group","EXPERIMENTAL","Patients in this group received ultrasound-guided bilateral anterior serratus plane block combined with bilateral pectoral-intercostal plane block after induction of general anesthesia and before surgical incision as part of the multimodal analgesia protocol.",[13],"Procedure: Combined ASPB and PIPB",{"label":15,"type":16,"description":17,"interventionNames":18},"ASPB Group:","ACTIVE_COMPARATOR","Patients assigned to the ASPB group underwent ultrasound-guided bilateral anterior serratus plane block following induction of general anesthesia and prior to skin incision. The block was incorporated into the perioperative multimodal analgesia protocol.",[19],"Procedure: Anterior Serratus Plane Block",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Combined ASPB and PIPB","Ultrasound-guided bilateral anterior serratus plane block combined with bilateral pectoral-intercostal plane block performed after induction of general anesthesia and before surgical incision to provide perioperative multimodal analgesia in patients undergoing cardiopulmonary bypass surgery.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Anterior Serratus Plane Block","Ultrasound-guided bilateral anterior serratus plane block performed after induction of general anesthesia and before surgical incision to provide perioperative analgesia in patients undergoing cardiopulmonary bypass surgery.",[15],[32],{"name":33,"affiliation":34,"role":35},"LEYLA KILINC","şişli etfal eğitim araştırma hastanesi","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"MUSTAFA ALTINAY","CONTACT","05333914422","m_altinay@yahoo.com",[43],{"facility":44,"status":26,"city":45,"state":26,"zip":46,"country":47,"countryCode":26,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Sisli etfal research and training hospital","Istanbul","34371","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],28.94966,41.01384,{"lat":52,"lon":51},[55],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Leyla Kılınc","associate professor","100648178","aspb-pipb-combination-in-cardiac-surgery-100648178",false,"NCT07716943","ASPB-PIPB Combination in Cardiac Surgery","Effects of Combined Anterior Serratus Plane and Pectoral-Intercostal Plane Blocks on Perioperative Analgesia and Enhanced Recovery After Surgery in Cardiopulmonary Bypass Surgery","Inclusion Criteria:\n\n* Patients undergoing open heart surgery via median sternotomy by the Cardiovascular Surgery Clinic\n* Patients over 18 years of age\n* ASA II-III patients\n\nExclusion Criteria:\n\n* \\- Patients undergoing emergency or recurrent surgery\n* Patients with left ventricular ejection fraction \\\u003C 30\n* Patients who died per-operatively\n* Patients who do not provide informed consent\n* Presence of chronic pain\n* Presence of allergy to local anesthetics\n* Presence of infection in the area where the block will be performed\n* Coagulopathy\n* Pre-existing neurological deficit\n* Mental retardation\n* Anatomical deformity","ALL","18 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications. Within Enhanced Recovery After Surgery (ERAS) protocols, multimodal analgesia and opioid-sparing strategies have become essential components of perioperative care. Ultrasound-guided fascial plane blocks, including the anterior serratus plane block (ASPB) and pectoral-intercostal plane block (PIPB), have emerged as effective and safe regional anesthesia techniques for cardiac surgery, targeting different sensory innervation of the thoracic wall. However, evidence regarding the combined use of these two blocks remains limited. This study aimed to evaluate whether the combination of ASPB and PIPB improves intraoperative and postoperative analgesia, reduces opioid consumption, and enhances postoperative recovery and ERAS outcomes compared with standard analgesic management in patients undergoing cardiopulmonary bypass surgery.",[77,78,79,80],"Postoperative Pain","Cardiac Surgery","Cardiopulmonary Bypass","Median Sternotomy",[79,77,82,83],"Regional Anesthesia","Enhanced Recovery After Surgery","NOT_YET_RECRUITING","2026-07-16",{"date":87,"type":88},"2026-07-21","ACTUAL",{"date":90,"type":71},"2026-07-01",{"date":92,"type":71},"2027-06-30",{"name":5,"class":6},1]