[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560653":3},{"organization":4,"outcomesModule":7,"designInfo":91,"detailedDescription":101,"studyPopulation":90,"armGroups":102,"interventions":113,"overallOfficials":117,"centralContacts":121,"locations":131,"responsibleParty":197,"collaborators":201,"id":233,"slug":234,"hasResults":235,"nctId":236,"briefTitle":237,"officialTitle":238,"acronym":239,"eligibilityCriteria":240,"healthyVolunteers":241,"sex":242,"minAge":243,"maxAge":90,"enrollmentInfo":244,"targetDuration":90,"studyType":247,"phases":248,"briefSummary":250,"conditions":251,"keywords":268,"overallStatus":146,"whyStopped":90,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":282,"completionDateStruct":284,"leadSponsor":286,"locationsCount":287},{"fullName":5,"class":6},"University of Auckland, New Zealand","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":20,"otherOutcomes":90},[9,13,17],{"measure":10,"description":11,"timeFrame":12},"Resting heart rate","Resting heart rate in beats per minute measured as the average of three readings in the left arm over one hour using Blip portable automated sphygmomanometers.","Eight measurements will be taken: one at baseline and seven over 12 months, covering three consecutive hottest months and four alternate months.",{"measure":14,"description":15,"timeFrame":16},"Blood glucose control","Three month average of blood glucose in mmol\u002Fmol measured as glycosylated hemoglobin (HbA1c) using capillary blood and the HemoCue® HbA1c 501 System.","Two measurements will be taken: one at baseline and one in the last month of three consecutive hottest months.",{"measure":18,"description":19,"timeFrame":12},"Depression","Self-reported presence and frequency of symptoms of depression assessed using aggregate score of the Patient Health Questionnaire 9 (PHQ-9). Minimum score of 0 and a maximum score of 27 with a higher score meaning a worse outcome.",[21,24,27,30,33,36,39,42,45,48,51,55,58,62,65,68,71,74,77,81,84,87],{"measure":22,"description":23,"timeFrame":12},"Heat-related symptoms","Self-reported heat-related symptoms in the past month, assessed using a recall questionnaire.",{"measure":25,"description":26,"timeFrame":12},"Physician diagnosed heat-related illnesses","Self-reported new diagnosis from a medical practitioner of a heat-related illness in the last month assessed using a recall questionnaire.",{"measure":28,"description":29,"timeFrame":12},"Food insecurity","Self-reported experience based measure of individual food security assessed using the Food Insecurity Experience Scale (FIES).",{"measure":31,"description":32,"timeFrame":12},"Diet quality","Self-reported individual food group consumption in the previous 24 hours assessed using the Diet Quality Questionnaire (DQQ).",{"measure":34,"description":35,"timeFrame":12},"Health-related quality of life","Current self-reported health-related quality of life assessed using the EuroQol EQ-5D-5L quality assessment tool. The minimum and maximum scores for the EuroQol EQ-5D-5L quality assessment tool are -0.59 and 1, respectively. A score of 1 represents the best possible health state, while scores below 0 indicate health states that are considered worse than death.",{"measure":37,"description":38,"timeFrame":12},"Indoor thermal comfort","Self-reported household heat, humidity and comfort experience over the last four weeks assessed using a recall questionnaire.",{"measure":40,"description":41,"timeFrame":12},"Coping ability","Self-reported coping strategies for high indoor temperatures assessed using a recall questionnaire.",{"measure":43,"description":44,"timeFrame":12},"Life satisfaction","Current self-reported life satisfaction assessed using the World Values Survey. Values can range from 1 to 10 with a higher score representing greater life satisfaction.",{"measure":46,"description":47,"timeFrame":12},"Healthcare provider utilization","Self-reported healthcare provider utilization in the past four weeks assessed using a recall questionnaire.",{"measure":49,"description":50,"timeFrame":12},"Hospitalization","Self-reported overnight hospital stay in the past four weeks assessed using a recall questionnaire.",{"measure":52,"description":53,"timeFrame":54},"Systolic Blood Pressure","Maximum blood pressure (mmHg) during systole measured as the average of three readings in the left arm over one hour using Blip portable automated sphygmomanometers.","Eight measurements will be taken: one at baseline and seven over 12 months, covering the three consecutive hottest months and four alternate months.",{"measure":56,"description":57,"timeFrame":54},"Diastolic Blood Pressure","Minimum blood pressure (mmHg) during diastole measured as the average of three readings in the left arm over one hour using Blip portable automated sphygmomanometers.",{"measure":59,"description":60,"timeFrame":61},"Cognition","Accuracy and response time to the four-choice Deary-Liewald Test measured using the CogniFit app-based assessment tool.","Eight measurements: one at baseline and seven over 12 months, covering three consecutive hottest months and four alternate months.",{"measure":63,"description":64,"timeFrame":54},"Inner Ear Canal Temperature","Internal body temperature (℃) measured once using Braun digital ear thermometer.",{"measure":66,"description":67,"timeFrame":12},"Dehydration","Dehydration as indicated by urine specific gravity ≥1.020 measured as urine specific gravity using Siemens Multistix SG dipstick.",{"measure":69,"description":70,"timeFrame":61},"Sleep quality","Self-reported sleep distrubance assessed using the Athens Insomnia Scale (AIS). Values range from 0 to 24 with a higher score indicating a worse outcome.",{"measure":72,"description":73,"timeFrame":61},"Aggression","Self-reported personal aggresion assessed using the Buss-Perry Aggression Questionnaire-Ultra Short Form (BPAQ-ML).",{"measure":75,"description":76,"timeFrame":54},"Productivity","Self-reported job absenteeism and presenteeism assessed using the Health and Work Performance Questionnaire Short Form (HPQ-SF).",{"measure":78,"description":79,"timeFrame":80},"Indoor air temperature","Indoor air temperature (℃) measured using Hobo MX1101 heat and humidity measurement device.","Measurements at 15 minute intervals for 12 months.",{"measure":82,"description":83,"timeFrame":80},"Indoor relative humidity","Ratio of the amount of water vapor present in the air to the greatest amount possible at the same temperature (%) measured using Hobo MX1101 heat and humidity measurement device.",{"measure":85,"description":86,"timeFrame":80},"Indoor heat index","Index that combines air temperature and relative humidity (℃) based on temperature and humidity measurements from the Hobo MX1101 heat and humidity measurement device calculated using the formulae endorsed by the US National Oceanic and Atmospheric Administration.",{"measure":88,"description":89,"timeFrame":54},"Household energy expenditure","Self-reported household energy expenditure assessed using a recall questionnaire from the head of the household.",null,{"allocation":92,"interventionModel":93,"interventionModelDescription":90,"primaryPurpose":94,"observationalModel":90,"timePerspective":90,"maskingInfo":95},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":96,"maskingDescription":97,"whoMasked":98},"DOUBLE","Trial participants will be aware of the intervention to which they have been allocated, and the research fieldworkers will be aware of the intervention allocation. The trial steering committee members and trial statistician will remain blinded until the end of trial period and data collection.",[99,100],"INVESTIGATOR","OUTCOMES_ASSESSOR","Increasing heat exposure from climate change is causing and exacerbating heat-related illnesses in millions worldwide - particularly in low resource settings. June 2024 was the 13th consecutive hottest month on record globally - shattering previous records. Heat exposure can instigate and worsen health conditions including cardiovascular, metabolic, endocrine and respiratory disease, heat-related illnesses, pregnancy complications, and mental health conditions. Adaptation is essential for protecting people from increasing heat exposure. The built environment, especially our homes, are ideal for deploying interventions to reduce heat exposure and accelerate adaptation efforts. However, currently there is a lack of evidence on a global scale - generated through empirical studies - guiding the uptake of interventions to reduce heat stress in low resource settings.\n\nSunlight-reflecting cool roof coatings passively reduce indoor temperatures and lower energy use, offering protection to home occupants from extreme heat. The investigators aim to conduct a global multi-centre cluster-randomized controlled trial investigating the effects of cool-roof use on health, environmental and economic outcomes in five urban climate hotspots - Ouagadougou, Burkina Faso (sub-Saharan Africa), Ahmedabad, India (Asia), Tavua, Fiji and Niue (Oceania), and Colima, Mexico (Latin America). The sites represent hotspots where people experience a triple burden from heat exposure, chronic health issues and vulnerable housing conditions (slums, informal settlements and low socioeconomic housing). They also exhibit diversity in climate profiles, housing typology, level of socioeconomic development, population density and rates of urbanisation.\n\nThe trial will quantify whether cool roofs are an effective passive home cooling intervention with beneficial health effects for vulnerable populations in four locations. Findings will inform global policy responses on scaling cool roof implementation to protect people from increasing heat exposure driven by climate change.",[103,109],{"label":104,"type":105,"description":106,"interventionNames":107},"Cool roof","EXPERIMENTAL","Households will receive sunlight reflecting 'cool roof' coating on their roofs.",[108],"Other: Cool roof",{"label":110,"type":111,"description":112,"interventionNames":90},"No cool roof","NO_INTERVENTION","No cool roof application. Households will keep their original roofing for the duration of the trial.",[114],{"type":6,"name":104,"description":115,"armGroupLabels":116,"otherNames":90},"Cool roofs are a sunlight reflecting roof coating that can reduce indoor temperature. Cool roofs have high solar reflectance (reflecting the ultraviolet and visible wavelengths of sunlight, reducing heat transfer to the surface of a roof) and high thermal emittance (radiating absorbed solar energy).",[104],[118],{"name":119,"affiliation":5,"role":120},"Collin Tukuitonga, Sir. Dr.","PRINCIPAL_INVESTIGATOR",[122,127],{"name":123,"role":124,"phone":125,"phoneExt":90,"email":126},"Aditi Bunker, Dr","CONTACT","+49 6221 565344","aditi.bunker@uni-heidelberg.de",{"name":119,"role":124,"phone":128,"phoneExt":129,"email":130},"+6493737599","89612","collin.tukuitonga@auckland.ac.nz",[132,144,160,171,189],{"facility":133,"status":134,"city":135,"state":90,"zip":90,"country":136,"countryCode":137,"cosmosGeoPoint":138,"geoPoint":143,"contacts":90},"University Joseph Ki-Zerbo","ACTIVE_NOT_RECRUITING","Ouagadougou","Burkina Faso","BF",{"type":139,"coordinates":140},"Point",[141,142],-1.53388,12.36566,{"lat":142,"lon":141},{"facility":145,"status":146,"city":147,"state":90,"zip":90,"country":148,"countryCode":149,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"Fiji National University","RECRUITING","Suva","Fiji","FJ",{"type":139,"coordinates":151},[152,153],178.42531,-18.13683,{"lat":153,"lon":152},[156],{"name":157,"role":124,"phone":158,"phoneExt":90,"email":159},"Donald Wilson","+6798053931","donald.wilson@fnu.ac.fj",{"facility":161,"status":134,"city":162,"state":163,"zip":90,"country":164,"countryCode":165,"cosmosGeoPoint":166,"geoPoint":170,"contacts":90},"Indian Institute of Public Health Gandhinagar","Ahmedabad","Gandhinagar","India","IN",{"type":139,"coordinates":167},[168,169],72.58727,23.02579,{"lat":169,"lon":168},{"facility":172,"status":173,"city":174,"state":175,"zip":90,"country":176,"countryCode":177,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"Instituto Tecnológico de Hermosillo","NOT_YET_RECRUITING","Hermosillo","Sanora","Mexico","MX",{"type":139,"coordinates":179},[180,181],-110.96677,29.08874,{"lat":181,"lon":180},[184,188],{"name":185,"role":124,"phone":186,"phoneExt":90,"email":187},"Jose Antonio Hoyo Montano","+526621610612","jose.hoyom@hermosillo.tecnm.mx",{"name":185,"role":120,"phone":90,"phoneExt":90,"email":90},{"facility":190,"status":134,"city":191,"state":90,"zip":90,"country":190,"countryCode":90,"cosmosGeoPoint":192,"geoPoint":196,"contacts":90},"Niue","Alofi",{"type":139,"coordinates":193},[194,195],-169.91957,-19.05294,{"lat":195,"lon":194},{"type":198,"investigatorFullName":199,"investigatorTitle":200,"investigatorAffiliation":5,"oldNameTitle":90,"oldOrganization":90},"SPONSOR_INVESTIGATOR","Aditi Bunker","Co-Principal Investigator",[202,205,207,209,212,214,216,218,220,222,224,226,228,230,231],{"name":203,"class":204},"Sika Services AG","UNKNOWN",{"name":206,"class":204},"SOPREMA",{"name":208,"class":204},"Engineered Polymer Solutions (EPS B.V.)",{"name":210,"class":211},"Resene","INDUSTRY",{"name":213,"class":6},"Pacific Community",{"name":215,"class":6},"Habitat for Humanity",{"name":217,"class":6},"The Tindall Foundation",{"name":219,"class":6},"Rutgers University",{"name":221,"class":6},"Boston University",{"name":223,"class":6},"London School of Hygiene and Tropical Medicine",{"name":225,"class":6},"Heidelberg University",{"name":227,"class":6},"University of Ouagadougou, Burkina Faso",{"name":229,"class":6},"Indian Institute of Public Health, India",{"name":145,"class":6},{"name":232,"class":6},"Universidad de Colima","100560653","assessing-the-effects-of-cool-roofs-on-indoor-environments-and-health-100560653",false,"NCT06579950","Assessing the Effects of Cool Roofs on Indoor Environments and Health","The Effects of Cool Roofs on Health, Environmental, and Economic Outcomes: a Global Multi-center Cluster-randomized Controlled Trial","REFLECT","Inclusion Criteria:\n\n* Permanent household resident.\n\nExclusion Criteria:\n\n* Roof damage, inaccessible or instability of roof adversely affecting cool roof coating application.\n* Participant unable to provide written\u002Fverbal informed consent.",true,"ALL","18 Years",{"count":245,"type":246},3200,"ESTIMATED","INTERVENTIONAL",[249],"NA","Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities. Sunlight-reflecting cool roof coatings passively reduce indoor temperatures and energy use to protect home occupants from extreme heat. Occupants living in poor housing conditions globally - for example in informal settlements, slums, and low-socioeconomic households - are especially vulnerable to increased indoor heat exposure.\n\nHeat exposure can instigate and worsen numerous physical, mental and social health conditions. The worst adverse health effects are being experienced in communities least able to adapt to heat exposure. By reducing indoor temperatures, cool roof use can promote physical, mental and social wellbeing in occupants.\n\nThe long-term research goal is to identify viable passive housing adaptation technologies with proven health and environmental benefits to reduce the burden of heat stress in communities affected by heat globally. To meet this goal, the investigators will conduct a cluster-randomized controlled trial to establish the effects of cool roof use on health, indoor environment and economic outcomes in five urban climate hotspots: Ouagadougou, Burkina Faso; Colima, Mexico; Ahmedabad, India; Niue; and Tavua, Fiji.",[252,253,18,254,255,256,257,258,259,260,261,262,49,52,56,63,66,263,59,75,72,264,265,266,267],"Resting Heart Rate","Blood Glucose Control","Heat-related Symptoms","Physician Diagnosed Heat-related Illnesses","Food Insecurity","Diet Quality","Health-related Quality of Life","Indoor Thermal Comfort","Coping Ability","Life Satisfaction","Healthcare Provider Utilization","Sleep Quality","Indoor Air Temperature","Indoor Relative Humidity","Indoor Heat Index","Household Energy Expenditure",[269,270,271,272,273,18,274,275,276,104,277],"Hot Temperature","Humidity","Housing","Heart rate","Cardiovascular","Mental health","Blood glucose","Diabetes","Heat Stress","2026-02-25",{"date":280,"type":281},"2026-02-27","ACTUAL",{"date":283,"type":281},"2024-09-04",{"date":285,"type":246},"2027-09-30",{"name":199,"class":6},5]