[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659297":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":13,"interventions":13,"overallOfficials":13,"centralContacts":19,"locations":25,"responsibleParty":48,"collaborators":13,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":13,"enrollmentInfo":60,"targetDuration":13,"studyType":63,"phases":13,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":28,"whyStopped":13,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Hospital, Strasbourg, France","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Diagnostic yield of invasive genetic testing in isolated IUGR","Proportion of invasive prenatal procedures identifying a genetic abnormality explaining the intrauterine growth restriction","2016-2023 retrospective period",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"CASE_ONLY","RETROSPECTIVE","This is a retrospective monocentric study conducted at Strasbourg University Hospitals including all cases of isolated IUGR diagnosed after 28 weeks of gestation between 2016 and 2023. The study evaluates the proportion of invasive prenatal procedures performed, their diagnostic yield, and factors influencing both indication and performance of amniocentesis. Data are extracted from the DIAMM database and completed using DEFGEN for postnatal genetic results.","Pregnant women managed at Strasbourg University Hospitals with isolated intrauterine growth restriction diagnosed after 28 weeks of gestation between 2016 and 2023.",[20],{"name":21,"role":22,"phone":23,"phoneExt":13,"email":24},"Marie-Laure LEGRIS, MD","CONTACT","33 3 88 12 73 02","marie-laure.legris@chru-strasbourg.fr",[26],{"facility":27,"status":28,"city":29,"state":13,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Service de Gynécologie et Obstétrique - CHU de Strasbourg - France","RECRUITING","Strasbourg","67091","France","FR",{"type":34,"coordinates":35},"Point",[36,37],7.74553,48.58392,{"lat":37,"lon":36},[40,41,43,46],{"name":21,"role":22,"phone":23,"phoneExt":13,"email":24},{"name":21,"role":42,"phone":13,"phoneExt":13,"email":13},"PRINCIPAL_INVESTIGATOR",{"name":44,"role":45,"phone":13,"phoneExt":13,"email":13},"Marie LAPLANE, MD","SUB_INVESTIGATOR",{"name":47,"role":45,"phone":13,"phoneExt":13,"email":13},"Johanne Stoerkel, Midwife",{"type":49,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100659297","assessment-of-invasive-genetic-testing-in-fetuses-with-isolated-intrauterine-growth-restriction-diagnosed-after-28-weeks-of-gestation-at-strasbourg-university-hospitals-2016-2023-100659297",false,"NCT07864272","Assessment of Invasive Genetic Testing in Fetuses With Isolated Intrauterine Growth Restriction Diagnosed After 28 Weeks of Gestation at Strasbourg University Hospitals (2016-2023)","Assessment of Invasive Genetic Testing Procedures in Fetuses With Isolated Intrauterine Growth Restriction (IUGR) Diagnosed After 28 Weeks of Gestation at Strasbourg University Hospitals Between 2016 and 2023","RCIU","Inclusion Criteria:\n\n* Maternal age ≥ 18 years\n* Referral after 28 weeks of gestation for estimated fetal weight \\\u003C 3rd percentile, isolated condition\n* Management at Strasbourg University Hospitals between 01\u002F01\u002F2016 and 01\u002F01\u002F2023\n* No documented opposition to reuse of medical data for research\n\nExclusion Criteria:\n\n* Suspected fetal structural anomaly or infectious cause\n* Multiple pregnancy\n* Incomplete genetic workup","FEMALE","18 Years",{"count":61,"type":62},200,"ESTIMATED","OBSERVATIONAL","This study evaluates the diagnostic yield of invasive genetic testing in fetuses with isolated intrauterine growth restriction diagnosed after 28 weeks of gestation, in order to better define indications for invasive procedures and improve clinical counseling.",[66],"Isolated Intrauterine Growth Restriction (IUGR)",[68,69,70],"IUGR","Amniocentesis","Fetal genetics","2026-10-02",{"date":73,"type":74},"2026-10-07","ACTUAL",{"date":76,"type":74},"2026-01-12",{"date":78,"type":62},"2027-01-12",{"name":5,"class":6},1]