[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650142":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":26,"centralContacts":27,"locations":36,"responsibleParty":66,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":91,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Medical University of Lodz","OTHER",[8,13,17],{"label":9,"type":6,"description":10,"interventionNames":11},"Chronic hemodialyzed patients","Patients with chronic kidney disease (CKD) G5 during chronic hemodialysis",[12],"Other: Preconditioning with control ischemic episodes",{"label":14,"type":6,"description":15,"interventionNames":16},"Patient with CKD G1-G5","Patient with CKD G1-G5 without patients during chronic hemodialysis",[12],{"label":18,"type":6,"description":19,"interventionNames":20},"Control group","Patients without CKD",[12],[22],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Preconditioning with control ischemic episodes","4 cycles of 5-minute inflation and deflation using a sphygmomanometer cuff at a pressure of 30 mmHg above the systolic value through three consecutive days",[9,18,14],null,[28,33],{"name":29,"role":30,"phone":31,"phoneExt":26,"email":32},"Michał Nowicki, Professor","CONTACT","+48 42 201 44 00","nefro@wp.pl",{"name":34,"role":30,"phone":31,"phoneExt":26,"email":35},"Katarzyna Pęczek-Bartyzel, MD PhD","katarzyna.peczek90@gmail.com",[37,59],{"facility":38,"status":39,"city":40,"state":26,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Medical University of Lodzi","RECRUITING","Lodz","90-213","Poland","PL",{"type":45,"coordinates":46},"Point",[47,48],19.47395,51.77058,{"lat":48,"lon":47},[51,53,54,57],{"name":34,"role":30,"phone":52,"phoneExt":26,"email":35},"48422014400",{"name":26,"role":30,"phone":26,"phoneExt":26,"email":35},{"name":55,"role":56,"phone":26,"phoneExt":26,"email":26},"Katarzyna Pęczek-Bartyzel, MD Phd","SUB_INVESTIGATOR",{"name":29,"role":58,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"facility":38,"status":39,"city":40,"state":26,"zip":60,"country":42,"countryCode":43,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"92-219",{"type":45,"coordinates":62},[47,48],{"lat":48,"lon":47},[65],{"name":34,"role":30,"phone":31,"phoneExt":26,"email":35},{"type":58,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Katarzyna Peczek-Bartyzel","Nephrologist","100650142","assessment-of-the-impact-of-repeated-ischemic-preconditioning-episodes-on-hemodynamic-and-metabolic-parameters-in-patients-at-various-stages-of-chronic-kidney-disease-100650142",false,"NCT07746102","Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease","Inclusion Criteria:\n\n* obtaining the patient's voluntary, informed consent to participate in the experiment,\n* chronic kidney disease in stages G1-G5,\n* women and men over 18 years of age.\n* failure to meet the qualification criteria for participation in the study,\n* consciousness disorders,\n* heart failure (NYHA IV),\n* severe anemia (Hb concentration\\\u003C8g\u002FdL),\n* features of muscle cell damage (e.g. rhabdomyolysis),\n* peripheral circulation disorders, peripheral vascular diseases.\n\nExclusion Criteria:\n\n\\-",true,"ALL","18 Years",{"count":79,"type":80},60,"ESTIMATED","INTERVENTIONAL",[83],"NA","The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases. There is credible evidence that intentionally producing periods of ischemia provides protection of the myocardium and blood vessels against subsequent ischemic injury. The examination will be performed during hospitalization in the Department of Nephrology, Hypertension, Transplantology and Internal Diseases and will last 4 days. On the first day, blood pressure will be measured using an automatic blood pressure monitor, radial artery pulse, blood saturation will be measured using a pulse oximeter, and approximately 6 ml of venous blood will be collected from the elbow bend area for laboratory tests. Then, compression of the lower limb below the knee will be performed using a blood pressure cuff. Four 5-minute cycles of inflation and deflation of the cuff will be performed. The pressure on the lower limb will be repeated on the next two days. On the last day of the examination, blood pressure, heart rate and blood saturation will be measured again, and approximately 6 ml of venous blood will be collected again for laboratory tests.",[86,87,88,89,90],"Hemodialysis","Ischemia Preconditioning","Chronic Kidney Disease","Blood Pressure Disorders","Inflammation",[86,92],"ischemia preconditioning","2026-08-03",{"date":95,"type":96},"2026-08-04","ACTUAL",{"date":98,"type":80},"2026-07-23",{"date":100,"type":80},"2026-12-31",{"name":5,"class":6},2]