[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648466":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":8,"responsibleParty":34,"collaborators":7,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":7,"enrollmentInfo":47,"targetDuration":50,"studyType":51,"phases":7,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":64,"whyStopped":7,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University Hospital, Geneva","OTHER",null,[9],{"facility":10,"status":7,"city":11,"state":7,"zip":12,"country":13,"countryCode":14,"cosmosGeoPoint":15,"geoPoint":20,"contacts":21},"University Hospital of Geneva","Geneva","1205","Switzerland","CH",{"type":16,"coordinates":17},"Point",[18,19],6.14569,46.20222,{"lat":19,"lon":18},[22,27,31,33],{"name":23,"role":24,"phone":25,"phoneExt":7,"email":26},"Giulia Frigerio, MD","CONTACT","+41795533139","giulia.frigerio@hug.ch",{"name":28,"role":24,"phone":29,"phoneExt":7,"email":30},"Axelle Serre, MD","+41795538642","axelle.serre@hug.ch",{"name":28,"role":32,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"name":23,"role":32,"phone":7,"phoneExt":7,"email":7},{"type":32,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Giulia Frigerio","Principal Investigator, M.D.","100648466","association-between-female-hormonal-profile-and-wound-healing-100648466",false,"NCT07724145","Association Between Female Hormonal Profile and Wound Healing","Association Between Female Hormonal Profile and Wound Healing Outcomes After Reduction Mammaplasty","FEMHEAL","Inclusion Criteria:\n\n* Symptomatic breast hypertrophy\n* Premenopausal\n\nExclusion Criteria:\n\n* Previous breast reduction surgery\n* Menopausal status\n* Oral contraceptives\n* Corticosteroid therapy\n* History of breast cancer\n* Active smoking and use of nicotine substitution products","FEMALE","18 Years",{"count":48,"type":49},84,"ESTIMATED","12 Months","OBSERVATIONAL","The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are:\n\n1. Does wound healing differ depending on whether the operation takes place before or after ovulation in the menstrual cycle?\n2. Does estradiol have a positive effect on wound healing?\n\nParticipants with mammary hypertrophy will undergo reduction mammaplasty, and the investigators will measure their hormonal profile (LH, FSH, and estradiol) on the day of surgery.",[54,55,56],"Wound Healing","Wound Healing Complication","Estradiol",[58,59,60,61,62,63],"wound healing","menstrual cycle","estradiol","hormones","dehiscence","reduction mammaplasty","NOT_YET_RECRUITING","2026-07-21",{"date":67,"type":68},"2026-07-23","ACTUAL",{"date":70,"type":49},"2026-07",{"date":72,"type":49},"2028-12",{"name":5,"class":6},1]