[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659022":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":16,"armGroups":17,"interventions":22,"overallOfficials":13,"centralContacts":27,"locations":13,"responsibleParty":33,"collaborators":13,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":41,"acronym":13,"eligibilityCriteria":42,"healthyVolunteers":43,"sex":44,"minAge":13,"maxAge":13,"enrollmentInfo":45,"targetDuration":48,"studyType":49,"phases":13,"briefSummary":50,"conditions":51,"keywords":13,"overallStatus":53,"whyStopped":13,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":13},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Clinical pregnancy rate","To compare the clinical pregnancy rate across prespecified serum progesterone categories on the day of embryo transfer and to estimate the association between progesterone level and clinical pregnancy.","1 year",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":6,"maskingInfo":13},"COHORT","All eligible HRT-FET cycles performed at the Assisted Reproductive Technology Unit, Department of Obstetrics and Gynaecology",[18],{"label":19,"type":13,"description":13,"interventionNames":20},"Patients with frozen-thawed embryo transfer cycles using hormone replacement therapy",[21],"Other: data collection",[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":13},"data collection","serum progesterone levels on embryo transfer day and clinical pregnancy",[19],[28],{"name":29,"role":30,"phone":31,"phoneExt":13,"email":32},"Chung PW Jacqueline","CONTACT","35051537","jacquelinechung@cuhk.edu.hk",{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Chung Pui Wah Jacqueline","Associate Professor","100659022","association-between-serum-progesterone-levels-on-embryo-transfer-day-and-clinical-pregnancy-in-frozen-thawed-embryo-transfer-cycles-using-hormone-replacement-therapy-a-retrospective-cohort-study-100659022",false,"NCT07858227","Association Between Serum Progesterone Levels on Embryo Transfer Day and Clinical Pregnancy in Frozen-thawed Embryo Transfer Cycles Using Hormone Replacement Therapy: a Retrospective Cohort Study","Inclusion Criteria:\n\n* HRT-FET cycles performed during the prespecified retrospective study period\n* Women aged 18 to \\\u003C42 years at the time of embryo transfer\n* BMI \\\u003C30 kg\u002Fm²\n* Transfer of at least one good-quality embryo\n* Serum progesterone measured on the morning of embryo transfer as part of routine care\n* Availability of the primary clinical pregnancy outcome in the medical record\n\nExclusion Criteria:\n\n* Severe or uncontrolled endocrine disorders documented at the time of treatment (e.g., thyroid dysfunction or premature ovarian insufficiency)\n* Untreated severe uterine factors likely to impair implantation (e.g., severe endometriosis, large or subendometrial fibroids, intrauterine adhesions, or endometrial polyps)\n* Missing or implausible key exposure data after source-data verification",true,"FEMALE",{"count":46,"type":47},300,"ESTIMATED","1 Day","OBSERVATIONAL","A retrospective evaluation of routinely collected clinical, embryological, laboratory, and pregnancy outcome data provides an efficient approach to examine the association between serum progesterone on the day of FET and clinical pregnancy in an Asian population.",[52],"Infertility Assisted Reproductive Technology","NOT_YET_RECRUITING","2026-09-30",{"date":56,"type":57},"2026-10-05","ACTUAL",{"date":59,"type":47},"2026-10-15",{"date":61,"type":47},"2032-10-31",{"name":5,"class":6}]