[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577522":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":68,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":26,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Auricular VNS Stimulation","EXPERIMENTAL","Participants receive twice daily auricular vagal nerve stimulation",[13],"Device: Auricular Vagus Nerve Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Auricular VNS Stimulation","SHAM_COMPARATOR","Participants will have an auricular vagal nerve stimulator placed in their ear twice daily, without the stimulation applied",[19],"Device: Sham Auricular Vagus nerve Stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Auricular Vagus Nerve Stimulation","Transcutaneous auricular vagal nerve stimulation",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Auricular Vagus nerve Stimulation","Transcutaneous auricular vagal nerve ear clip applied without current",[15],[32],{"name":33,"affiliation":5,"role":34},"Eric Leuthardt, MD MBA","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Raj Dhar, MD","CONTACT","314-362 2999","dharr@wustl.edu",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","St Louis","Missouri","63110","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-90.19789,38.62727,{"lat":53,"lon":52},[56,60,64,66],{"name":57,"role":38,"phone":58,"phoneExt":26,"email":59},"Juliana Amaral Passipieri, PhD","314-747-1443","ajuliana@wustl.edu",{"name":61,"role":38,"phone":62,"phoneExt":26,"email":63},"Elma Heric, BS","314-362-3570","elmah@wustl.edu",{"name":33,"role":65,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"name":37,"role":67,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":69,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100577522","auricular-vns-following-intracerebral-hemorrhage-100577522",false,"NCT06799390","Auricular VNS Following Intracerebral Hemorrhage","Vagus Nerve Stimulation Following Intracerebral Hemorrhage (IHC) to Mitigate ICH-induced Inflammation and Cerebral Edema","Inclusion Criteria:\n\n* Adult patients who present with a spontaneous supratentorial intracerebral hemorrhage (ICH) to Barnes Jewish Hospital\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years old\n* Patients with a presumed traumatic etiology for their ICH, infratentorial location, ICH volume \\> 60 ml or \\\u003C 10 ml, at risk of imminent death (e.g. Glasgow Coma Scale, GCS of 3 or one or more pupils unreactive), surgical intervention imminently planned (not including ventriculostomy)\n* Patients undergoing active cancer therapy\n* Patients with sustained bradycardia on arrival with a heart rate \\\u003C 50 beats per minute.\n* Patients who cannot be enrolled within 48 hours of the initial bleed.","ALL","18 Years",{"count":80,"type":81},80,"ESTIMATED","INTERVENTIONAL",[84],"NA","This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following intracerebral hemorrhage.",[87],"Intracerebral Hemorrhage",[89,90,91,92,93,94,95,96,97],"vagal nerve stimulation","pathologic processes","intracerebral hemmorrhage","cerebrovascular disorders","brain diseases","Central Nervous System Diseases","Nervous System Diseases","Vascular Diseases","Hemorrhage","2026-07-01",{"date":100,"type":101},"2026-07-06","ACTUAL",{"date":103,"type":101},"2025-04-06",{"date":105,"type":81},"2032-02-09",{"name":5,"class":6},1]