[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649080":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":34,"centralContacts":38,"locations":45,"responsibleParty":68,"collaborators":43,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":43,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":48,"whyStopped":43,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Autogenic Drainage Group","EXPERIMENTAL","Participants assigned to this arm will receive therapist-guided autogenic drainage, an airway clearance technique that uses controlled breathing at different lung volumes to mobilize secretions from peripheral to central airways. Treatment sessions will be administered five times per week for six weeks, with each session lasting approximately 10 minutes under physiotherapist supervision.",[13],"Procedure: Autogenic Drainage",{"label":15,"type":10,"description":16,"interventionNames":17},"Mechanical Percussion Group","Participants assigned to this arm will receive mechanical chest percussion therapy using a high-frequency percussion device to facilitate airway secretion clearance. Treatment sessions will be administered five times per week for six weeks, with each session lasting approximately 10 minutes under physiotherapist supervision.",[18],"Device: Mechanical Percussion",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Autogenic Drainage","Autogenic drainage is a breathing-based airway clearance technique designed to mobilize and remove bronchial secretions. Participants will receive therapist-guided autogenic drainage sessions consisting of controlled breathing at low, medium, and high lung volumes to facilitate mucus movement from peripheral to central airways. Treatment sessions will be conducted under physiotherapist supervision for approximately 10 minutes per session, five times per week, for six weeks.",[9],[26],"Airway Clearance Technique AD",{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Mechanical Percussion","Mechanical percussion is an airway clearance intervention that utilizes a mechanical percussion device to generate rhythmic vibrations over the chest wall to loosen and mobilize pulmonary secretions. Participants will receive supervised mechanical percussion therapy for approximately 10 minutes per session, five times per week, for six weeks. Treatment will be delivered according to standardized clinical procedures, with device settings adjusted to participant tolerance and clinical response.",[15],[33],"Mechanical Chest Percussion Chest Percussion Therapy High-Frequency Percussion Therapy",[35],{"name":36,"affiliation":5,"role":37},"Humera Ayub, MS-CPPT","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Imran Amjad, PhD","CONTACT","03324390125",null,"imran.amjad@riphah.edu.pk",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Nishter Hospital Multan","RECRUITING","Multan Khurd","Punjab Province","59300","Pakistan","PK",{"type":55,"coordinates":56},"Point",[57,58],72.01752,33.03555,{"lat":58,"lon":57},[61,65],{"name":62,"role":41,"phone":63,"phoneExt":43,"email":64},"Humera Ayub, MS CPPT","+923045938096","humera.ayub@riphah.edu.pk",{"name":66,"role":67,"phone":43,"phoneExt":43,"email":43},"Muhammad Farhan Faiz, MS-CPPT","SUB_INVESTIGATOR",{"type":69,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR","100649080","autogenic-drainage-versus-mechanical-percussion-in-children-with-cystic-fibrosis-100649080",false,"NCT07729787","Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis","Comparative Effects of Autogenic Drainage and Mechanical Percussion on Lung Function, Dyspnea and Quality of Life in Children With Cystic Fibrosis","ADMP-CF","Inclusion Criteria:\n\n* Confirmed diagnosis of cystic fibrosis (CF) through a sweat test or genetic testing.\n* Age between 6 and 12 years.\n* Clinically stable condition (no acute pulmonary exacerbation within the last 4 weeks).\n\nExclusion Criteria:\n\n* History of thoracic surgery.\n* Active hemoptysis.\n* Severe physical or cognitive disabilities limiting participation in the intervention or assessments.","ALL","6 Years","12 Years",{"count":82,"type":83},32,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to compare the effects of autogenic drainage and mechanical percussion on lung function, dyspnea, and quality of life in children with cystic fibrosis.\n\nThe main questions it aims to answer are:\n\n* Does autogenic drainage improve lung function more effectively than mechanical percussion in children with cystic fibrosis?\n* Does autogenic drainage reduce dyspnea (breathlessness) more effectively than mechanical percussion?\n* Does autogenic drainage improve health-related quality of life more effectively than mechanical percussion?\n\nResearchers will compare autogenic drainage with mechanical percussion to determine which airway clearance technique provides greater benefits for children with cystic fibrosis.\n\nParticipants will:\n\n* Be randomly assigned to receive either autogenic drainage or mechanical percussion therapy.\n* Participate in supervised treatment sessions five times per week for six weeks.\n* Undergo assessments of lung function using spirometry (FEV₁ and FVC), dyspnea using the Modified Borg Dyspnea Scale, and quality of life using the Cystic Fibrosis Questionnaire-Revised (CFQ-R) before and after the intervention period.\n\nThe findings of this study may help identify the most effective airway clearance technique for improving respiratory health and quality of life in children with cystic fibrosis.",[89],"Cystic Fibrosis (CF)",[91,22,29,92,93,94,95,96],"Cystic Fibrosis","Airway Clearance Techniques","Chest Physiotherapy","Pulmonary Function","Spirometry","Dyspnea","2026-07-27",{"date":99,"type":100},"2026-07-28","ACTUAL",{"date":102,"type":100},"2026-06-14",{"date":104,"type":83},"2026-11-30",{"name":5,"class":6},1]