[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648133":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":58,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Universidad de Murcia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Fixed Orthodontic Retention","ACTIVE_COMPARATOR","Participants assigned to this arm will receive a fixed lingual orthodontic retainer bonded to the mandibular anterior teeth, extending from tooth 33 to tooth 43. The same retainer wire and bonding materials will be used for all participants",[13],"Device: Fixed Orthodontic Retainer",{"label":15,"type":16,"description":17,"interventionNames":18},"Removable Essix-Type Orthodontic Retention","EXPERIMENTAL","Participants assigned to this arm will receive a clear removable Essix-type orthodontic retainer. Participants will be instructed to wear the retainer for 22 hours per day. All retainers will be manufactured using the same material and by the same dental technician.",[19],"Device: Removable Essix-Type Orthodontic Retainer",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Fixed Orthodontic Retainer","A fixed lingual orthodontic retainer bonded to the mandibular anterior teeth, extending from tooth 33 to tooth 43",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Removable Essix-Type Orthodontic Retainer","A clear removable Essix-type orthodontic retainer prescribed for 22 hours of daily wear",[15],[32],{"name":33,"affiliation":5,"role":34},"Antonio J Ortiz Ruiz, MD PhD","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Ascensión Vicente, DDS PhD","CONTACT","+3486888664","ascenvi@um.es",[42],{"facility":43,"status":44,"city":45,"state":26,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"University Dental Clinic","RECRUITING","Murcia","30008","Spain","ES",{"type":50,"coordinates":51},"Point",[52,53],-1.13004,37.98704,{"lat":53,"lon":52},[56],{"name":37,"role":38,"phone":57,"phoneExt":26,"email":40},"+34868888664",{"type":59,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100648133","bacterial-diversity-study-using-16s-rrna-sequencing-of-periodontal-samples-from-patients-with-orthodontic-retainers-100648133",false,"NCT07718061","Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic Retainers","Ortho-Perio","Inclusion Criteria:\n\n* Treatment involving both dental arches\n* Permanent dentition with at least 24 teeth\n* Treatment duration longer than 12 months\n* Treatment using the Versatile MBT system with a 0.022-inch slot\n\nExclusion Criteria:\n\n* Patients with systemic disease or taking medications that may affect periodontal health\n* Inadequate restorations or active carious lesions\n* iodontal disease\n* Plaque index greater than 20% before placement of the retainer or during the study\n* Use of oral antiseptics within the previous 6 months or during the study period\n* Use of antibiotics within the previous 14 days or during the study period\n* Smokers\n* Pregnant or breastfeeding women\n* Presence of open gingival embrasures, crowding, or dental malposition in the mandibular anterior region after orthodontic treatment","ALL","18 Years","40 Years",{"count":71,"type":72},10,"ESTIMATED","INTERVENTIONAL",[75],"NA","After completion of orthodontic treatment, a retention phase is required to prevent relapse of tooth malposition. Fixed retention in the mandibular anterior region is commonly used. This type of retainer is bonded to the lingual surfaces of the canines and incisors and may hinder oral hygiene, thereby promoting bacterial plaque accumulation and gingival inflammation.\n\nCurrently, probably due to the increasing use of clear aligner therapy, clear removable Essix-type retainers are becoming more widely used. Since these retainers can be removed by the patient, they may facilitate oral hygiene. However, studies assessing gingival health and the composition of the subgingival microbiota in patients wearing orthodontic retainers remain scarce.\n\nTherefore, the aim of this study will be to assess the composition of the gingival sulcus microbiota and gingival health in patients wearing fixed or removable orthodontic retainers.\n\nTen adult patients who have completed orthodontic treatment will be recruited and divided into two groups:\n\n1. Fixed retention group.\n2. Removable retention group.\n\nPeriodontal parameters will be assessed, and bacterial plaque samples will be collected from the gingival sulcus at five time points:\n\nT0: Bracket removal and dental scaling appointment. Periodontal parameters will be assessed, and plaque samples will be collected before bracket debonding and dental scaling.\n\nT1: Retainer placement appointment, three days after T0. Periodontal parameters will be assessed, and plaque samples will be collected before retainer placement.\n\nT2: One month after retainer placement.\n\nT3: Three months after retainer placement.\n\nT4: Six months after retainer placement.",[23,78,79,80,81],"Orthodontic Appliances, Removable","Orthodontic Appliance Complication","Gingivitis","Periodontal Diseases",[83,84,80,85],"Orthodontic retainer","Periodontal health","Microbiota","2026-07-27",{"date":88,"type":89},"2026-07-28","ACTUAL",{"date":91,"type":89},"2026-01-12",{"date":93,"type":72},"2027-07",{"name":5,"class":6},1]