[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100396254":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":63,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1",null,"Patients with choroidal neovascularization in the context of age-related macular degeneration or central serous chorioretinopathy",[13],"Other: Blood and aqueous humor biomarker of treatment response",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","Control group : patients without choroidal neovascularization",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"OTHER","Blood and aqueous humor biomarker of treatment response","Blood analyses and aqueous humor analysis",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Francine Behar-Cohen, Dr","CONTACT","01 44 27 81 64","francine.cohen@aphp.fr",[31,49],{"facility":32,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Ophtalmopole Hôpital Cochin","RECRUITING","Paris","75014","France","FR",{"type":39,"coordinates":40},"Point",[41,42],2.3488,48.85341,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":47,"phoneExt":10,"email":48},"Francine Pr. Behar-Cohen","+33660974419","Francine.cohen@aphp.fr",{"facility":50,"status":33,"city":51,"state":10,"zip":52,"country":36,"countryCode":37,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Hôpital Foch","Suresnes","92150",{"type":39,"coordinates":54},[55,56],2.22929,48.87143,{"lat":56,"lon":55},[59],{"name":60,"role":27,"phone":61,"phoneExt":10,"email":62},"Vincent Pierre-Khan","+331462275","pkahnv@gmail.com",{"type":64,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100396254","biomarkers-and-choroidal-neovascularization-100396254",false,"NCT04439708","Biomarkers and Choroidal Neovascularization","Biomarkers Analysis of Mineralocortoid Receptor Activation in the Serum and Ocular Fluid of Patients With Choroidal Neovascularization","BioNéoRet","Inclusion Criteria:\n\nPatients of group 1:\n\n* Patients with type 1 choroidal neovascularization in a context of central serous chorioretinoathy or age related macular degeneration\n* Patients without intravitreal injection or last intravitreal injection \\> 3 months\n* Informed signed consent\n\nPatients of group 2:\n\n* Patients without choroidal neovascularization\n* Patients with intraocular surgery (cataract or vitrectomy surgery)\n* Signed consent\n\nExclusion Criteria:\n\n* Myocardial infarction \\\u003C 12 months\n* Chronic renal failure\n* Inflammatory disease\n* Infectious disease :HIV, viral hepatitis, tuberculosis\n* Type 1 or 2 Diabetes\n* Patients treated by mineralocorticoid antagonist treatment.\n* Type 2 or 3 choroidal neovascularization\n* Pregnant woman","ALL","18 Years","90 Years",{"count":77,"type":78},250,"ESTIMATED","OBSERVATIONAL","The aim of the study is to find biomarkers in the blood and aqueous humor of patients with type 1 choroidal neovascularization and correlate them with the response to anti-VEGF treatment.",[82,83],"Choroidal Neovascularization","Mineralocorticoid Excess",[85,86,87],"central serous chorioretinopathy","age related macular degeneration","biomarker","2026-07-03",{"date":90,"type":91},"2026-07-07","ACTUAL",{"date":93,"type":91},"2020-07-06",{"date":95,"type":78},"2027-07-06",{"name":5,"class":6},2]