[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652370":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":56,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":10,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"CSM",null,"All Adults over age of 18, with a diagnosis of\u002Fencompassed by\u002Frelated to cervical spondylotic myelopathy, cervical myelopathy, or ossification of posterior longitudinal ligament.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy, non-CSM","Adults over age of 18, with no neck pain, radiculopathy, or myelopathy symptoms, and no trauma in the past 6 months. Does not meet exclusion criteria.",[16],{"name":17,"affiliation":18,"role":19},"Nima Alan, MD","University of California San Francisco, Department of Neurological Surgery","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Danielle Nieto, BA","CONTACT","5102102469","danielle.nieto@ucsf.edu",{"name":27,"role":23,"phone":10,"phoneExt":10,"email":28},"Catherine Ravikumar, MS","catherine.ravikumar@ucsf.edu",[30],{"facility":31,"status":10,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"UCSF Medical Center","San Francisco","California","94143","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-122.41942,37.77493,{"lat":41,"lon":40},[44,46,47,50,52,54],{"name":22,"role":23,"phone":45,"phoneExt":10,"email":25},"415-476-5199",{"name":17,"role":19,"phone":10,"phoneExt":10,"email":10},{"name":48,"role":49,"phone":10,"phoneExt":10,"email":10},"Ethan Winkler, MD, PhD","SUB_INVESTIGATOR",{"name":51,"role":49,"phone":10,"phoneExt":10,"email":10},"Lee Tan, MD",{"name":53,"role":49,"phone":10,"phoneExt":10,"email":10},"Praveen Mummaneni, MBA, MD",{"name":55,"role":49,"phone":10,"phoneExt":10,"email":10},"Jang Yoon, MD",{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100652370","biomarkers-of-cervical-spondylotic-myelopathy-100652370",false,"NCT07772297","Biomarkers of Cervical Spondylotic Myelopathy","Investigating -Omic Features and Prognostic Indicators of Cervical Spondylotic Myelopathy","Healthy Inclusion Criteria:\n\n* Age \\>18\n* No neck pain\n* No radiculopathy or myelopathy symptoms\n* No trauma in the past 6 months\n* Does not meet exclusion criteria.\n\nCSM Inclusion Criteria:\n\n* Age \\>18\n* Diagnosis of\u002Fencompassed by\u002Frelated to cervical spondylotic myelopathy, cervical myelopathy, ossification of posterior longitudinal ligament.\n\nHealthy Exclusion Criteria:\n\n* Age \\\u003C18.\n* Malignancy\n* Trauma in the past 6 months\n* Infectious etiology\n* Prior cervical spine surgery.\n* Symptoms of cervical radiculopathy, myelopathy or neck pain.\n\nCSM Exclusion Criteria:\n\n* Age \\\u003C18.\n* Malignancy\n* Trauma in the past 6 months\n* Infectious etiology.\n* Prior cervical spine surgery.\n* MRI or CT imaging demonstrating an alternative cause for cervical myelopathy that is not degenerative stenosis (i.e. transverse myelitis, tumor compressing cord, pathologic fracture).",true,"ALL","18 Years",{"count":69,"type":70},50,"ESTIMATED","OBSERVATIONAL","Investigators believe that patients with cervical spondylotic myelopathy (CSM) have measurable changes in certain molecules in their blood compared with people without CSM. Investigators expect that these changes may be related to how severe a patient's condition is based on imaging and clinical exams. Investigators will also study how these molecules change before and after surgery to see whether they are related to how well patients recover. By combining these blood markers with clinical and imaging information, investigators hope to develop a tool that may help predict patient outcomes.",[74],"Cervical Spondylotic Myelopathy",[74,76,77],"spine","Biomarkers","NOT_YET_RECRUITING","2026-08-18",{"date":81,"type":82},"2026-08-20","ACTUAL",{"date":84,"type":70},"2026-09",{"date":86,"type":70},"2030-09",{"name":5,"class":6},1]