[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645688":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":41,"eligibilityCriteria":42,"healthyVolunteers":37,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":57,"overallStatus":62,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Ukrainian Society of Regional Anesthesia and Pain Therapy","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Regional Anesthesia Burden",null,"Regional Anesthesia Burden represents the cumulative extent of regional anesthesia received during the acute management of polytrauma, including the number of peripheral nerve blocks, continuous peripheral nerve catheters, cumulative local anesthetic exposure, anatomical regions treated, and procedural complexity.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Dmytro Dmytriiev, PhD.Professor","CONTACT","+380674309449","dmytrodmytriiev@gmail.com",[19],{"facility":20,"status":10,"city":21,"state":10,"zip":22,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":10},"Vinnitsya university hospital","Vinnytsia","21000","Ukraine","UA",{"type":26,"coordinates":27},"Point",[28,29],28.46871,49.2322,{"lat":29,"lon":28},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dmytro Dmytriiev","PhD, Professor","100645688","block-trauma-study-100645688",false,"NCT07702071","BLOCK-TRAUMA Study","Regional Anesthesia Burden and Clinical Outcomes in Polytrauma Patients: A Prospective Cohort Study","BLOCK-TRAUMA","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Diagnosis of polytrauma, defined as traumatic injuries involving two or more anatomical regions.\n* Injury Severity Score (ISS) ≥16.\n* Hospital admission within 48 hours after injury.\n* Requirement for acute pain management during hospital treatment.\n* Receipt of at least one ultrasound-guided peripheral nerve block and\u002For continuous peripheral nerve catheter as part of routine clinical care.\n* Ability to collect clinical data on regional anesthesia procedures, analgesic use, pain assessment, and early recovery outcomes.\n* Written informed consent provided by the patient or legally authorized representative, according to local regulations.\n\nExclusion Criteria:\n\n* Age younger than 18 years.\n* Isolated single-system injury without polytrauma. ISS \\\u003C16.\n* Expected survival less than 24 hours after admission.\n* Severe traumatic brain injury or impaired consciousness preventing reliable pain and functional assessment, unless validated behavioral pain scales can be used.\n* Known allergy or contraindication to local anesthetics.\n* Pre-existing severe neuromuscular disease affecting motor function assessment.\n* Chronic opioid therapy before injury.\n* Pregnancy.\n* Enrollment in another interventional trial that may affect pain management or functional recovery outcomes.\n* Missing essential data required for assessment of Regional Anesthesia Burden.","ALL","18 Years","50 Years",{"count":47,"type":48},500,"ESTIMATED","OBSERVATIONAL","This prospective cohort study will evaluate the association between the overall burden of regional anesthesia and early clinical outcomes in adult patients with polytrauma.\n\nPatients with severe trauma often experience pain from multiple injury sites and may require more than one peripheral nerve block or continuous regional anesthesia catheter. While regional anesthesia can improve pain control and reduce opioid use, multiple blocks and catheters may also increase treatment complexity, local anesthetic exposure, motor weakness, and monitoring challenges.\n\nThe study will prospectively collect data on the number and type of regional anesthesia procedures, local anesthetic exposure, catheter use, pain intensity, opioid consumption, mobility, complications, and early recovery outcomes. The goal is to determine whether increasing regional anesthesia burden is associated with improved analgesia, functional recovery, or increased risk in polytrauma patients.",[52,53,54,55,56],"Polytrauma","Regional Anaesthesia","Nerve Block","Acute Pain","Combat Trauma",[52,58,59,55,60,61],"Regional Anesthesia","Peripheral Nerve Block","Local Anesthetics","Combat Injury","NOT_YET_RECRUITING","2026-07-09",{"date":65,"type":66},"2026-07-14","ACTUAL",{"date":68,"type":48},"2026-07-23",{"date":70,"type":48},"2026-10-23",{"name":5,"class":6},1]