[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658151":3},{"organization":4,"outcomesModule":7,"designInfo":13,"detailedDescription":11,"studyPopulation":11,"armGroups":19,"interventions":31,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":41,"collaborators":11,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":11,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":72,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":11},{"fullName":5,"class":6},"Hospital del Mar","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":11,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Pressure Pain Threshold mesured with presure algometry at the center of the Patella",null,"Baseline to 12 months after surgery",{"allocation":14,"interventionModel":15,"interventionModelDescription":11,"primaryPurpose":16,"observationalModel":11,"timePerspective":11,"maskingInfo":17},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":18,"maskingDescription":11,"whoMasked":11},"NONE",[20,26],{"label":21,"type":22,"description":23,"interventionNames":24},"Bone-Patellar Tendon-Bone Autograft","EXPERIMENTAL","Bone-Patellar Tendon-Bone Autograft Arm Participants will undergo primary anterior cruciate ligament (ACL) reconstruction using a bone-patellar tendon-bone (BPTB) autograft harvested from the central portion of the patellar tendon, with bone blocks approximately 9-10 mm in diameter and 10-20 mm in length. The graft will be implanted using the standardized arthroscopic ACL reconstruction technique routinely performed at the study center.",[25],"Procedure: Bone-Patellar Tendon-Bone Autograft ACL Reconstruction",{"label":27,"type":22,"description":28,"interventionNames":29},"Quadriceps Tendon Autograft","Quadriceps Tendon Autograft arm Participants will undergo primary anterior cruciate ligament reconstruction using a quadriceps tendon autograft with a bone block approximately 9-10 mm in diameter and 10-20 mm in length. The graft will be harvested as a partial-thickness graft using a standardized technique and implanted using the same standardized arthroscopic ACL reconstruction principles.",[30],"Procedure: Quadriceps Tendon Autograft ACL Reconstruction",[32,37],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":11},"PROCEDURE","Bone-Patellar Tendon-Bone Autograft ACL Reconstruction","BPTB Autograft ACL Reconstruction Primary ACL reconstruction using an autologous bone-patellar tendon-bone graft harvested from the central patellar tendon, with bone blocks approximately 9-10 mm in diameter and 10-20 mm in length. Graft harvest and reconstruction will be performed using a standardized arthroscopic technique",[21],{"type":33,"name":38,"description":39,"armGroupLabels":40,"otherNames":11},"Quadriceps Tendon Autograft ACL Reconstruction","Quadriceps Tendon Autograft ACL Reconstruction Primary ACL reconstruction using an autologous quadriceps tendon graft with a bone block approximately 9-10 mm in diameter and 10-20 mm in length. The graft will be harvested as a partial-thickness quadriceps tendon graft using a standardized technique and implanted arthroscopically.",[27],{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Carlos Torrens","orthopedic surgeon","100658151","bone-patellar-tendon-bone-versus-quadriceps-tendon-autograft-for-anterior-cruciate-ligament-reconstruction-a-non-inferiority-trial-regarding-anterior-knee-pain-100658151",false,"NCT07846709","Bone-Patellar Tendon-Bone Versus Quadriceps Tendon Autograft for Anterior Cruciate Ligament Reconstruction: A Non-Inferiority Trial Regarding Anterior Knee Pain","Randomized Non-inferiority Clinical Trial Comparing Anterior Knee Pain After Anterior Cruciate Ligament Reconstruction With Bone-Patellar Tendon-Bone Autograft Versus Quadriceps Tendon Autograft","BTB vs QT","Inclusion Criteria:\n\nClinical and\u002For radiological diagnosis of an anterior cruciate ligament (ACL) injury with an indication for primary surgical reconstruction.\n\nAbility to understand the study information and provide written informed consent.\n\nWillingness to participate in the study and complete the planned clinical and radiological follow-up.\n\nTechnical feasibility of performing either a bone-patellar tendon-bone (BPTB) autograft or a quadriceps tendon autograft, as determined by the treating surgeon.\n\nExclusion Criteria Previous surgery on the affected knee. Previous fracture of the proximal tibia, distal femur, or patella of the affected knee.\n\nHistory of patellofemoral pain syndrome, symptomatic insertional patellar tendinopathy, or symptomatic insertional quadriceps tendinopathy.\n\nNeed to harvest a graft that does not meet the predefined study specifications. Presence of a pain-amplifying condition or generalized chronic pain that could interfere with the assessment of anterior knee pain.\n\nPsychiatric, cognitive, or mental health disorders that may impair follow-up, understanding of the study, or valid completion of questionnaires.\n\nMedical contraindication to surgery or magnetic resonance imaging (MRI). Refusal to participate or withdrawal of informed consent.","ALL","18 Years","55 Years",{"count":57,"type":58},150,"ESTIMATED","INTERVENTIONAL",[61],"NA","This prospective, randomized, single-center, non-inferiority clinical trial will compare anterior knee pain (AKP) after primary anterior cruciate ligament (ACL) reconstruction using either a bone-patellar tendon-bone autograft (BPTB) or a quadriceps tendon autograft with a bone block (BQT).\n\nParticipants will be randomly assigned in a 1:1 ratio to one of the two graft groups. The primary objective is to determine whether BPTB is non-inferior to BQT with respect to AKP, as assessed by the change in pressure pain threshold from the preoperative measurement to 12 months after surgery.\n\nSecondary outcomes will include kneeling pain, the Kujala Anterior Knee Pain Scale, the visual analog scale (VAS) for pain, quadriceps muscle circumference, the subjective International Knee Documentation Committee (IKDC) score, magnetic resonance imaging (MRI) findings, clinical stability, complications, associated surgical procedures, and graft failure.",[64],"Anterior Cruciate Ligament (ACL) Tear",[66,67,68,69,70,71],"Anterior cruciate ligament reconstruction","Bone-patellar tendon-bone autograft","Quadriceps tendon autograft","Anterior knee pain","Pressure algometry","Randomized clinical trial","NOT_YET_RECRUITING","2026-10-03",{"date":75,"type":76},"2026-10-07","ACTUAL",{"date":78,"type":58},"2026-10-05",{"date":80,"type":58},"2029-10",{"name":5,"class":6}]