[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657079":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":28,"studyPopulation":21,"armGroups":29,"interventions":40,"overallOfficials":21,"centralContacts":46,"locations":21,"responsibleParty":52,"collaborators":21,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":21,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":80,"whyStopped":21,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":21},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":21},[9],{"measure":10,"description":11,"timeFrame":12},"Identification of possible early AD","Using MoCA and retinal Image AD Index to screening participants who have high risk of Alzheimer's Disease","At baseline",[14,17],{"measure":15,"description":16,"timeFrame":12},"Investigation of the control in AD modifiable risk factors","Using the brain health scores to identify AD modifiable risk factors: (a) cardiovascular risk factors, (b) level of physical activity, (c) level of cognitively stimulating\u002Fsocial activities (CSA)",{"measure":18,"description":19,"timeFrame":20},"Implementation of AD preventive measures","Base on the result of brain health score, tailor-made preventive measures among early AD subjects with suboptimal control in risk factors. Compare the results of brain health score after completion of health educational programs. Programs end time varies as they are tailor-made; yet evaluations will be done at 12 month and 24 months after baseline evaluation.","End of educational program(s) approximately at 12 months and 24 months",null,{"allocation":23,"interventionModel":24,"interventionModelDescription":21,"primaryPurpose":25,"observationalModel":21,"timePerspective":21,"maskingInfo":26},"NON_RANDOMIZED","PARALLEL","SCREENING",{"masking":27,"maskingDescription":21,"whoMasked":21},"NONE","Epidemiological studies over the past few decades demonstrate that AD is associated with multiple modifiable risk factors, including cardiovascular risk factors, level of physical and cognitively stimulating or social activities, and dietary pattern. Recent large scale randomized controlled clinical trials show that single- or multi-domain lifestyle intervention and control in cardiovascular risk factors can slow down cognitive decline among subjects with early AD who have suboptimal control in AD modifiable risk factors.\n\nThis study aims to identify subjects with possible early AD, to investigate the control in AD modifiable risk factors among subjects with early AD, and to implement tailor-made preventive measures among early AD subjects with suboptimal control in risk factors.\n\nThrough the BEAT AD program, knowledge on preventive measures of AD can be promoted around Hong Kong.",[30,34],{"label":31,"type":32,"description":33,"interventionNames":21},"Healthy Control","NO_INTERVENTION","Cognitive unimpaired",{"label":35,"type":36,"description":37,"interventionNames":38},"MCI","ACTIVE_COMPARATOR","Mild Cognitive impaired",[39],"Behavioral: medical referral and\u002For educational programs",[41],{"type":42,"name":43,"description":44,"armGroupLabels":45,"otherNames":21},"BEHAVIORAL","medical referral and\u002For educational programs","tailor-made multidomain preventive measures plan about diet, exercises, cognitive stimulation",[35],[47],{"name":48,"role":49,"phone":50,"phoneExt":21,"email":51},"Pauline Kwan, Master's Degree","CONTACT","+852 26352160","paulinekwan@cuhk.edu.hk",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"PRINCIPAL_INVESTIGATOR","Vincent Mok","Professor","100657079","brain-heath-service-for-prevention-of-ad-100657079",false,"NCT07834528","Brain Heath Service for Prevention of AD","BEAT AD","Inclusion Criteria:\n\n* 1\\. Hong Kong citizens, between 55 - 80 years old.\n\nExclusion Criteria:\n\n* 1\\. No known diagnosis of dementia or other diseases that may affect cognition, e.g., stroke, Parkinson's disease, brain infection, major head injury, major depression, obstructive sleep apnea, alcoholism (e.g., daily \\> 2 standard drinks for male and \\> 1 standard drinks for woman).\n* 2\\. Subject who cannot understand Cantonese",true,"ALL","55 Years","80 Years",{"count":68,"type":69},4000,"ESTIMATED","INTERVENTIONAL",[72],"NA","The aim of the program to serve as a prototype for future preventive program for AD in the region. The program will recruit elderly participants. Cognitive assessment and lifestyle questionnaire will be performed with each participant to investigator their risk factor associate with AD.\n\nThe program will offer medical referral and\u002For educational program(s) (e.g. tailor-made multidomain preventive measures plan, education talks) for participants who might have possible early AD or with high risk of AD",[75,76,77],"Alzheimer","Cognitive Unimpaired","Mild Cognitive Impairment",[79],"lifestyle modification in prevention of AD","NOT_YET_RECRUITING","2026-09-16",{"date":83,"type":84},"2026-09-22","ACTUAL",{"date":86,"type":69},"2026-10-20",{"date":88,"type":69},"2033-03-31",{"name":5,"class":6}]